Pediatrics. Consilium Medicum

The journal publishes the works of scientists and practicing pediatricians, including experts in the field of neonatology, gastroenterology, otolaryngology, pulmonology, cardiology, endocrinology, allergy, dermatology, rheumatology, dentistry, clinical pharmacology, neurology, nutrition, emergency care in Russia and CIS countries. During its existence the magazine has gained wide recognition among professionals. 

 

Main sections: Healthy child, neonatology, endocrinology, otolaryngology and pulmonology, allergology, gastroenterology, cardiology, interdisciplinary problem, childhood infections, methods of diagnosis and treatment, the results of the original clinical trials, scientific reviews, scientific events reports. 

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Current Issue

No 2 (2025)

Articles

Lactation dominant: How does a woman make her choice? A review
Zakharova I.N., Sugian N.G., Orobinskaya Y.V.
Abstract

Breast milk has numerous health benefits, but in high-income countries, breastfeeding rates remain below the recommended. Support and promotion of exclusive breastfeeding in the first months of life contributes to the reduction of morbidity and mortality and ensures the optimal development of the child. The timely start of feeding, skin-to-skin contact, professional support from healthcare personnel, and family motivation all play a crucial role. Educational programs and counseling are particularly important in the first days after birth, and an integrated approach that includes training, professional support, and enabling environments is a promising method to improve the rates of exclusive breastfeeding and any breastfeeding.

Pediatrics. Consilium Medicum. 2025;(2):114-119
pages 114-119 views
The impact of breast augmentation and breast reduction surgery on breastfeeding: a pediatrician's view. A review
Zakharova I.N., Pupykina V.V., Orobinskaya Y.V.
Abstract

Plastic surgery to change breast size, both enlargement and reduction, are becoming more and more popular. At the same time, breastfeeding is recognized as an ideal food for a child and an important factor in the health and development of a child. Therefore, the issue of the impact of these operations on the possibility and effectiveness of breastfeeding is relevant and requires careful consideration. The article provides information on the influence of various factors on breastfeeding, such as the types of implants, the time elapsed after surgery, surgical access during surgery, the location of implants, the presence of complications during breast enlargement, the preservation of sensitivity of the nipple-alveolar complex, blood supply. Therefore, when making a decision to perform plastic surgery on the breast, it is necessary to be aware of all the associated risks, both short-term and long-term.

Pediatrics. Consilium Medicum. 2025;(2):120-124
pages 120-124 views
The mysterious bifidus factor: A review
Zakharova I.N., Sugian N.G., Orobinskaya Y.V.
Abstract

Breast milk (BM) is a complex biological mixture that comprises fats, proteins, enzymes, antibodies, and other essential nutrients, providing babies with the necessary energy and serving as a crucial immunological barrier. It plays a key role in the development of the gastrointestinal tract microbiota in newborns, which is dominated by Bifidobacterium spp. This selective growth of beneficial bacteria is associated with the presence of oligosaccharides in human milk, which have a prebiotic function. Lack of such beneficial microbial components in children who are not breastfed can lead to impaired gastrointestinal function, making them more susceptible to various infectious agents and diseases. That is why infant formula manufacturers have started experimenting with adding artificially synthesized oligosaccharides to baby food to bring it closer to the BM composition. The next step was the introduction into baby foods of oligosaccharides naturally present in the BM. This approach proved successful: due to the addition of oligosaccharides, the microbiome of children became increasingly similar to that developed during breastfeeding, contributing to the improvement of the health and development of babies. These findings suggest that the oligosaccharides contained in human milk are a bifidus factor. One key component is lacto-N-biose I (LNB), a type I disaccharide that is an important building block of BM oligosaccharides. LNB exhibits potent prebiotic activity, stimulating the growth of various Bifidobacterium strains in the intestine and demonstrating significant potential for use in baby’s nutritional products and supplements. Similarly, artificially synthesized galactooligosaccharides and fucosylated oligosaccharide, 2-fucosyl lactose, structurally homologous to BM oligosaccharide, have an anti-inflammatory effect and are widely used in infant formula, complementing the means to support the health of babies.

Pediatrics. Consilium Medicum. 2025;(2):125-130
pages 125-130 views
"Unequal" marriage: What should the pediatrician expect from the offspring? A review
Zakharova I.N., Sugian N.G., Orobinskaya Y.V., Pupykina V.V., Tolkunova A.A., Arkhipova A.G.
Abstract

The influence of the age of parents at the time of conception and pregnancy of the mother on the development of children is the subject of constant debate and research. Although modern medicine has made significant advances in reproductive health, age limitations for conception and pregnancy are still relevant. Having children from one or two middle-aged parents carries certain benefits and potential risks for both parents and their offspring. The literature review addresses some potential risks of an “unequal” marriage.

Pediatrics. Consilium Medicum. 2025;(2):131-136
pages 131-136 views
Formation of proper toilet skills as a key element of prevention and therapy of functional constipation: from the physiology of bowel movements to practical solutions: A review
Zakharova I.N., Pupykina V.V.
Abstract

The article is devoted to a comprehensive approach to the analysis of functional constipation through the prism of the formation of physiologically correct toilet skills, a factor that is often underestimated by clinicians, but largely determines both the occurrence of the problem and the long-term result of its treatment. The first part of the review describes in detail the anatomical and physiological foundations of the act of defecation, including neuro-reflex mechanisms, pelvic floor muscle coordination, and the role of intra-abdominal pressure. Next, the pathogenesis of chronic functional constipation and dyssynergic defecation is considered, and their connection with behavioral disorders is emphasized: omission of urges, "postponement" of emptying, inadequate posture and psychological discomfort. The central place is given to the strategy of purposeful education of proper toilet skills in children and adults: choosing a fixed time, using a physiological position (footrest), limiting distracting elements and creating a calm atmosphere. Thus, a rational combination of knowledge about the anatomy and physiology of the act of defecation, early recognition of functional disorders, timely application of a set of preventive and therapeutic measures aimed at the formation of proper toilet skills can achieve positive results in solving this issue and improve the quality of life of patients.

Pediatrics. Consilium Medicum. 2025;(2):137-142
pages 137-142 views
Teething syndrome in infants: competent correction of symptoms. A review
Skakodub A.A., Kozlitina I.A., Filatova O.O., Ugai D.V.
Abstract

Teething in children is a normal physiological process consisting of the intraosseous movement of a tooth in the jaw until it appears in the oral cavity. This process may be accompanied by local and systemic symptoms. Currently, local medicinal and non-medicinal treatments for teething syndrome are recommended. As part of an integrated approach, it is rational to use Cholisal® dental gel, which has the necessary levels of safety for infants and effectiveness when used according to the instructions.

Pediatrics. Consilium Medicum. 2025;(2):143-149
pages 143-149 views
Do we use all the options of topical therapy for upper respiratory tract inflammatory conditions? A review
Radtsig E.Y., Kulmakova M.A.
Abstract

Anti-infectious immunity is a combination of mechanisms and responses that the body uses to resist external pathogens. The article describes the protective properties of one of these external barriers, the respiratory tract (RT) mucosa, as well as the factors affecting it and ways to correct the consequences of adverse effects. Methods for preventing or reducing the number of seasonal respiratory diseases and reducing the impact of adverse environmental factors are described, and data on the effect of topical drugs on the functional state of the RT epithelium and mucosa in the context of choosing the most "safe" drug without loss of clinical efficacy are presented. New data on the antiviral and anti-inflammatory activity of Euphorbium Compositum® Nasentropfen s nasal spray show that this topical agent helps to maintain the integrity of the epithelial barrier and improves the overall immunological and barrier functions of the RT ciliated epithelium and mucosa.

Pediatrics. Consilium Medicum. 2025;(2):150-154
pages 150-154 views
Evaluation of the effectiveness of correction of cicatricial deformation of soft tissues in the lumbar region using laser phoresis of a gel containing heparin and cepalin in patients with myelodysplasia
Guseva N.B., Eremin D.B., Ignateva L.V., Romashin M.A.
Abstract

Introduction. Myelodysplasia is a collective term that combines a large group of spinal cord malformations with typical localization (most often within the LI-SV segments). If myelodysplasia manifests as a myelocele, it requires urgent surgical intervention in the first hours after the child’s birth to excise the myelocyte. Treatment and rehabilitation of such children include using technical means of rehabilitation (TMR): orthoses, mobile vehicles, compression garments, etc. Success in the treatment and socialization of the patient depends on an individual approach for selecting TMRs and their maximum fit to the child’s body. In many cases, mature deforming scars of the lumbosacral region in a child challenge achieving the goal of rehabilitation and socialization of a disabled child.

Aim. To evaluate the effectiveness of the local therapy regimen, including laser phoresis of the drug with proteolytic activity, Contractubex gel, and its subsequent application to the scar tissue area without laser phoresis in disabled children after surgical excision of a myelocele. The therapy’s effectiveness criteria include softening and flattening old hypertrophic scars, increasing range of motion, decreasing tissue tension in the lumbosacral region, and improving the scar’s aesthetic condition.

Materials and methods. The main group included 20 children, 8 females and 12 males. The children were 5–17 years old, with a mean age of 11 years. The control group included 20 children (7 females, 13 males) aged 2–16, with a mean age of 11. Contractubex gel, manufactured by Merz Pharma LLC, was used to treat mature postoperative scars of the lumbosacral region in 20 main group patients. Proposed method and treatment regimen: 7 daily procedures of laser phoresis of the gel on the scar area, followed by switching to daily topical gel application without laser phoresis for 3 months. Evaluated indicators included scar width, size, color, pigmentation, vascularization, density, itching in the scar area, pain, feeling of skin tension, limited mobility, defects on the scar (cracks, wounds, ulcers), aesthetic discomfort, and quality of life. Each indicator was evaluated with 0 to 4 points, where 0 is the absence of a sign, and 4 is the most pronounced dissatisfaction with the sign. Statistical analysis was performed using the Page test.

Results. As a result of the therapy using the proposed regimen, in the main group, there was an improvement in the quality of life of children of 24±3 points and the achievement of positive results in several criteria at once, such as a decrease in pigmentation and vascularization of the scar, a decrease in the density of the scar and a decrease in the feeling of tension in the soft tissues surrounding the scar. According to the study findings in the main group, the average score before the start of treatment was 21 points vs. 16 points after the treatment. In the comparison group, the average baseline score was 18 vs. 17 at the end of the study. Improvements in the main group of patients led to increased quality of life and the possibility of more comfortable use of various TMRs that affect the scar area (locomats, exercise machines, corsets, etc.).

Conclusion. Correction of mature postoperative scars in the lumbosacral region in children operated for myelocele with a Contractubex containing onion extract (Cepalin), heparin, and allantoin according to the regimen with sequential use of laser phoresis and application of the drug without laser phoresis to the scar area has shown its effectiveness and is quite promising. The proposed therapy method helps to solve such problems as increasing the range of motion, the possibility of using TMRs, reducing the tension of the surrounding tissues, and improving the esthetics of the scar.

Pediatrics. Consilium Medicum. 2025;(2):156-162
pages 156-162 views
Children and tattoo: medical aspects. A review
Pupykina V.V., Orobinskaya Y.V., Zakharova I.N.
Abstract

Today, the issue of tattooing among children and adolescents is becoming increasingly relevant, when individuality and self-expression are the predominant aspects of modern life. Despite the growing popularity, the medical aspects of this phenomenon require careful consideration. From a medical point of view, tattooing a child is associated with a number of risks. Children's skin is thinner and more sensitive, which increases the likelihood of developing infections, allergic reactions and other consequences, especially unauthorized tattooing. The article analyzes the potential main causes of children's desire to get tattoos, as well as possible complications, including pyoderma, connective tissue diseases, autoimmune diseases and malignant neoplasms.

Pediatrics. Consilium Medicum. 2025;(2):164-170
pages 164-170 views
Tuberculosis of peripheral lymph nodes in adolescents as a manifestation of a generalized specific process: Clinical case
Panova L.V., Borisova T.N., Ovsyankina E.S., Bagirov M.A.
Abstract

Tuberculosis of peripheral lymph nodes is extremely rare, so when patients first contact a pediatrician due to enlargement of lymph nodes, it may be challenging to establish the correct diagnosis. To conduct a differential diagnosis between tuberculosis and nonspecific diseases, it is necessary to consider the medical history, paying special attention to the presence of contact with a patient with tuberculosis, and conducting a set of tests available to pediatricians and surgeons in general polyclinics and hospitals. The presented clinical case demonstrates the missed opportunities for timely diagnosis of tuberculosis in an adolescent, which led to the generalization of the specific process with involvement of peripheral lymph nodes and required several surgical interventions.

Pediatrics. Consilium Medicum. 2025;(2):171-175
pages 171-175 views
The use of low-temperature argon plasma in children’s practice: A review
Gromova A.A., Nalbandyan R.T., Medinskiy P.V.
Abstract

Background. Currently, the issue of treating wounds and their purulent-inflammatory complications in pediatric surgery remains highly relevant. The modern approach to treating wounds and wound infections is based on the method of active surgical treatment and includes performing surgical treatment, conducting local treatment with modern wound dressings, and treating with various methods of additional physical impact. Special attention is paid to plasma technology, which remains poorly studied and has no clear indications for use in pediatric practice, particularly in the treatment of extensive soft tissue damage of various etiologies, including open limb injuries.

Materials and methods. In this work, the analysis of domestic and foreign literature on the use of plasma technologies in various fields of medicine based on domestic and foreign data: eLIBRARY, PubMed, Google Scholar and UpToDate over the past 10 years. To search for relevant literature, the following keywords were used: low-temperature argon plasma; extensive wounds in children; plasma technology in medicine. During the initial selection, 962 sources of literature were found, 41 were included in the review.

Results. Literature analysis has shown the effectiveness of plasma technologies in various fields of medicine. The features of this method of exposure in various modes to tissues are described, as well as the technical aspects of its use in surgery are indicated.

Conclusion. Complicated by surgical infection, the course of the wound process leads to an increase in the volume of tissue damage, which hinders reconstructive and plastic surgeries. The use of low-temperature argon plasma in combination with traditional methods of surgical treatment allows for the rapid preparation of the wound surface for the final stages of surgical treatment. This is achieved by reducing bacterial contamination of infected wounds and stimulating reparative processes.

Pediatrics. Consilium Medicum. 2025;(2):176-182
pages 176-182 views
Human herpes viruses in pediatric burns. A common problem for pediatricians and surgeons. A retrospective study
Oborkina D.S., Budkevich L.I., Kozmova M.N., Grushitskaya E.V.
Abstract

Introduction. Impaired immune status is common in children with burns, which contributes to the reactivation of persistent herpes infections (HI). The clinical presentation of a viral infection does not always fall within the scope of the classical manifestations of an infectious disease. Therefore, pediatricians and surgeons must work closely to ensure adequate treatment and diagnostic approaches in this category of patients.

Aim. A brief review of the literature on this topic and a summary of the results of the retrospective study on the features of the course, diagnosis, and treatment of HI in children with thermal injury.

Materials and methods. We conducted a retrospective review of the medical records of children with burns treated in the specialized department of the Speransky Children’s City Clinical Hospital No. 9, from 2022 to 2024 with a hospital stay of 3 or more days. The study included 718 patients [522 (73%) males and 196 (27%) females] aged 1 to 165 months [median (Me) 16 months]. Of these, 110 (15%) were tested for HI. The indications for the test included fever (>38°C) for two or more days during antibacterial therapy for burn wounds and the absence of any signs of acute respiratory viral infection. The type of viral infection, the need for surgery, and the duration of inpatient treatment were evaluated.

Results. Sixty-seven (9.3%) of 718 patients had laboratory-confirmed HI. The median age of children with burns and confirmed HI was 16 months [interquartile range (ICR): 13–21]. Most children with confirmed HI were males (45 [67.2%]). The average burn area was 6% of the body surface (ICR 5-9). Baseline fever reached 38.7°C (ICR 38.3–39). In patients with thermal injury, the most common were herpes virus type 6 (28 [41.8%] patients) and cytomegalovirus (15 [22.4%] patients). The overall duration of hospital stay of patients was 7 days (ICR 5–9) and 8 days (ICR 6–10) in patients with a confirmed HI, suggesting an extension of the treatment duration (p<0.05). Surgery was performed in 25.9% of patients in the overall group and 31.3% of children with HI activation (p>0.05). Thus, the infection was not associated with a higher rate of surgical interventions for deep skin lesions.

Conclusion. HI in children presented with fever and was detected only during differential diagnosis with other infectious complications. Activation of the infection leads to longer treatment due to slower regeneration; however, it is not considered a risk factor for surgical intervention. The choice of a topical treatment is based on many factors. When managing wounds with a suspected viral and bacterial association, it is recommended to avoid the use of occlusive dressings. Our experience shows that dressings based on an aqueous iodine solution are preferable in such situations.

Pediatrics. Consilium Medicum. 2025;(2):183-190
pages 183-190 views