ENDOSCOPIC HEMOSTASIS IN PORTAL ESOPHAGEAL HEMORRHAGES AMONG PATIENTS WITH HEPATIC CIRRHOSIS


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Abstract

M State Academy of Medicine named after Academician E. A. Wagner, Perm, Russian Federation Aim. To assess the efficiency of combined endoscopic hemostasis technique in case of esophageal portal hemorrhages according to intrahospital lethality criteria and one-year survival rate among patients with hepatic cirrhosis (HC). Materials and methods. Retrospective analysis of treatment of 33 HC patients with portal hypertension syndrome, complicated esophageal dilated varicose veins (EDVV) hemorrhage over the period of 2008-2012 is presented in the paper. 21 patients of the main group underwent endoscopic ligation (EL) combined with endoscopic sclerotherapy (ES) of EDVV; 14 patients of the comparison group underwent EL alone. Results. In the main group, patients’ intrahospital lethality was lower (9,5% vs 33,3%), but one-year survival rate - higher (71,4% vs 66,7%) than in the comparison group. Conclusion. Combined endoscopic hemostasis in HC patients with EDVV hemorrhage is accompanied by decrease in intrahospital lethality and rise in one-year survival rate.

References

  1. Аль-Сабунчи О. М. Обоснование принципов малоинвазивной хирургии в профилактике и лечении кровотечений из варикозно-расширенных вен пищевода: автореф. дис. … д-ра мед. наук. М. 2007; 40.
  2. Назыров Ф. Г., Девятов Р. А., Ибадов Ш. Х. Результаты лечения больных циррозом печени после портосистемного шунтирования. Хирургия. Журнал им. Н. И. Пирогова 2008; 10: 32-35.
  3. Распереза Д. В. Сишкова Е. А. Оценка эффективности эндоскопического лигирования и комбинированного лечения (лигирование + склерозирование) в профилактике варикозных кровотечений при циррозе печени. Вестник Санкт-Петербургского университета 2008; 11 (1): 140-147.
  4. Шерцингер А. Г., Жигалова С. Б., Лебезев В. М., Манукьян Г. В., Киценко И. А. Современное состояние проблемы хирургического лечения больных портальной гипертензией. Хирургия 2013; 2: 30-34.
  5. Abraldes J. G., Villanueva C., Bañares R., Aracil C., Catalina M. V., Garci A-Pagán J. C., Bosch J. Hepatic venous pressure gradient and prognosis in patients with acute variceal bleeding treated with pharmacologic and endoscopic therapy. Journal of Hepatology 2008; 48: 229-236.
  6. Boyer T. D., Haskal Z. J. AASLD Practice Guidelines: the role of transjugular intrahepatic portosystemic shunt (TIPS) in the management of portal hypertension: Update 2009. Hepatology 2010; 51 (1): 1-16.
  7. Cales P., Pascal J. P. Histoire naturelle des varices oesophagiennes au cours de la cirrhose (de la naissance a la rupture). Gastroenterologie clinique et biologique 1988; 12: 245-54.
  8. D’Amico G., De Franchis R. Upper digestive bleeding in cirrhosis. Post-therapeutic outcome and prognostic indicators. Hepatology 2003; 38: 599-612.
  9. Franchis R., de Revising consensus in portal hypertension: Report of the Baveno V consensus workshop on methodology of diagnosis and therapy in portal hypertension. Journal of Hepatology 2010; 4: 762-768.
  10. Garcia-Tsao G., Sanyal A. J., Grace N. D., Carey W. Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis. Hepatology 2007; 46 (3): 922-938.
  11. Karsan H. A., Morton S. C., Shekelle P. G., Spiegel B. M., Suttorp M. J., Edelstein M. A., Gralnek I. M. Combination endoscopic band ligation and sclerotherapy compared with endoscopic band ligation alone for the secondary prophylaxis of esophageal variceal hemorrhage: a meta-analysis. Digestive Diseases and Sciences 2005; 50 (2): 399-406.
  12. Krige J. E., Kotze U. K., Bornman P. C., Shaw J. M., Klipin M. Variceal recurrence, rebleeding, and survival after endoscopic injection sclerotherapy in 287 alcoholic cirrhotic patients with bleeding esophageal varices. Ann. Surg. 2006; 244 (5): 764-770.
  13. Lo G. H., Lai K. H., Cheng J. S., Huang R. L., Wang S. J., Chiang H. T. Prevalence of paraesophageal varices and gastric varices in patients achieving variceal obliteration by banding ligation and by injection sclerotherapy. Gastrointestinal Endoscopy 1999; 49: 428-436.
  14. Lo G. H., Lai K. H., Cheng J. S., Lin C. K., Huang J. S., Hsu P. I., Huang H. C., Chiang H. T. The additive effect of sclerotherapy to patients receiving repeated endoscopic variceal ligation: a prospective, randomized trial. Hepatology 1998; 28: 391-395.
  15. Mašalaitė L., Valantinas J., Stanatis J. Recurrence of esophageal varices after endoscopic band ligation: single centre experience. Acta Medica Lituanica 2012; 19 (2): 59-66.
  16. Rössle M., Siegerstetter V., Huber M., Ochs A. The first decade of the transjugular intrahepatic portosystemic shunt (TIPS): state of the art. Liver 1998; 18: 73-89.
  17. Sarin S. K., Govil A., Jain A. K., Guptan R. C., Issar S. K., Jain M., Murthy N. S. Prospective randomized trial of endoscopic sclerotherapy versus variceal band ligation for esophageal varices: influence on gastropathy, gastric varices and variceal recurrence. Journal of Hepatology 1997; 26 (4): 826-832.
  18. Tajiri T., Yoshida H., Obara K., Onji M., Kage M., Kitano S., Kokudo N., Kokubu S., Sakaida I., Sata M., Tajiri H., Tsukada K., Nonami T., Hashizume M., Hirota S., Murashima N., Moriyasu F., Saigenji K., Makuuchi H., Oho K., Yoshida T., Suzuki H., Hasumi A., Okita K., Futagawa S., Idezuki Y. General rules for recording endoscopic findings of esophageal varices. Digestive Endoscopy 2010; 22: 1-9.
  19. Tessari L. Nouvelle technique d’obtention de la scle´ro-mousse. Phlebologie 2000; 53: 129-133.
  20. Thinrungroj N., Pisespongsa P., Kijdamrongthum A. L., Thinrungroj N. Alginate Accelerates Healing of post-endoscopic variceal ligation ulcers: a randomized-controlled trial. Gastrointestinal Endoscopy 2012; 75 (4S): AB457.
  21. Zargar S. A., Javid G., Khan B. A., Yattoo G. N., Shah A. H., Gulzar G. M., Singh J., Rehman B. U., Din Z. Endoscopic ligation compared with sclerotherapy for bleeding esophageal varices in children with extrahepatic portal venous obstruction. Hepatology 2002; 36 (3): 666-672.

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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
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