Temperature of animals and enhanced pressure of nitrogen-oxygen mixture

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Abstract

The rat thermoregulation in conditions of enhanced pressure in inhalation gas environment was assessed both experimentally and using mathematical model. All experiments were carried out on rats in barocamera, where the pressure of gas environment was increased gradually up to 4.1 МPа. The pressure enhancement of gas environment up to 2.1 MPa stimulated oxygen consumption in 1.7-fold, when pressure enhancement up to 4.1 MPa did it up to 2.3-fold. The thermoneutral zone of rats was gradually reduced in these conditions, e.g. with enhancement of preasure. Using mathematical model we have shown that pressure enhancement up to 2.1 MPa in barocamera increased thermodelivery in 1.9-fold whereas pressure enhancement up to 4.1 MPa did it in 2.6-fold.

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About the authors

Yury I Luchakov

IP Pavlov Institute of Physiology, Russian Academy of Sciences

Author for correspondence.
Email: yluchakov@yandex.ru
Dr. Biol. Sci. (Physiology), Scientific Researcher Russian Federation

Alexandr N Vyotosh

IM Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences

Email: vetosh@mail.ru
Dr. Biol. Sci. (Physiology), Senior Researcher Russian Federation

Petr D Shabanov

SM Kirov Military Medical Academy

Email: pdshabanov@mail.ru
Dr. Med. Sci. (Pharmacology), Professor and Head, Dept. of Pharmacology Russian Federation

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Copyright (c) 2016 Luchakov Y.I., Vyotosh A.N., Shabanov P.D.

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