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A prognostic efficiency of short-term tests - systems at an estimation of cancerogenic activity of chemical compounds
- Authors: Abilev S.K1, Tarasov A.V1, Tarasov V.A1
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Affiliations:
- N.I. Vavilov Institute of General Genetics RAS, Moscow, RF
- Issue: Vol 2, No 4 (2004)
- Pages: 12-21
- Section: Articles
- URL: https://journals.eco-vector.com/ecolgenet/article/view/5522
- DOI: https://doi.org/10.17816/ecogen2412-21
- ID: 5522
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Abstract
The method of an estimation prognostic efficiency of the battery of short-term tests at an estimation of potential cancerogenic activity of chemicals is offered. Levels of validity of cancerogenic activity 83 chemical compounds is carried out results at their testing in battery tests - test Ames, the test for SCE in cells in vitro, and the MNT - test in vivo. Researched date base is used as the trainee for forecasting potential cancerogenic activity of new chemical compounds by a method of cross-check
About the authors
Serikbay K Abilev
N.I. Vavilov Institute of General Genetics RAS, Moscow, RF
Email: serikbai@mail.ru
Aleksey V Tarasov
N.I. Vavilov Institute of General Genetics RAS, Moscow, RF
Valentin A Tarasov
N.I. Vavilov Institute of General Genetics RAS, Moscow, RF
Email: vat.vigg@mail.ru
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