Email this article 
The influence of prostaglandin analogs on the retinal thickness after phacoemulsification with intraocular lens implantation in primary open-angle glaucoma patients
- Authors: Astakhov S.Y.1, Astakhov Y.S.1, Gobedzhishvili M.V.1
-
Affiliations:
- I. P. Pavlov State Medical University of St. Petersburg
- Issue: Vol 7, No 3 (2014)
- Pages: 73-76
- Section: Articles
- URL: https://journals.eco-vector.com/ov/article/view/352
- DOI: https://doi.org/10.17816/OV2014373-76
- ID: 352
Cite item
Full Text
Abstract
Retinal OCT measurements were analyzed after phacoemulsification with intraocular lens (IOL) implantation in primary open-angle glaucoma (POAG) patients. A total of 190 patients (205 eyes) were examined. Two different groups were analyzed. Patients in Group 1 (32 eyes) had been treated with prostaglandin analogs before surgery (phacoemulsification or phacoemulsification + pressure lowering procedure) and after it when needed. However, these drops were stopped one day prior to surgery. Patients in Group 2 (173 eyes) were used as the control. The mean follow-up period after surgery was 12 months. During the entire follow-up period, in all patients had OCT monitoring at the 2nd-3rd day after surgery, 1 month, 2 months, 6 months, and 12 months. The OCT measurements were not statistically different between Group 1 (32 eyes) and Group 2 (173 eyes). According to our results, there was no significant influence of pre-operative prostaglandin use on the retinal thickness when compared to patients not using this therapy.
Keywords
About the authors
Sergey Yuryevich Astakhov
I. P. Pavlov State Medical University of St. Petersburg
Email: astakhov73@mail.ru
MD, doctor of medical science, professor, head of the department. Department of Ophthalmology
Yuriy Sergeyevich Astakhov
I. P. Pavlov State Medical University of St. Petersburg
Email: astakhov73@mail.ru
MD, doctor of medical science, professor. Department of Ophthalmology
Medeya Vakhtangovna Gobedzhishvili
I. P. Pavlov State Medical University of St. Petersburg
Email: astakhov73@mail.ru
MD, candidate of medical science, ophthalmologist. Department of Ophthalmology
References
- Алексеев И. Б., Самойленко А. И., Адлейба О. А. и др. Влияние аналогов простагландинов на результаты факоэмульсификации катаракты у больных первичной открытоугольной глаукомой. Российский офтальмологический журнал. 2012; 2: 4-7.
- Астахов С. Ю. Современные методы хирургической реабилитации больных катарактой и глаукомой: Автореф. Дис. Д-ра мед. наук. ВМА СПб, 1999; 37.
- Добромыслов А. Н., Квасова М. Д. Экстракция катаракты посе антиглаукомной операции. Вест. Офт. 1986; 102(3): 20-1.
- Одабашьян С. А. Роль перекисного окисления липидов в возникновении воспалительной реакции после экстракции катаракты с имплантацией ИОЛ. Офтальмол. журн., 2000; 3: 53-6.
- Biro Z., Balla Z., Kovacs B. Change of foveal and perifoveal thickness measured by OCT after phacoemulsification and IOL implantation. Eye (Lond), 2008; 22(1): 8-12.
- Bito L. Z., Camras C. B., Gum G. G., Resul B. The Ocular Hypotensive Effects and Side Effects of Prostaglandins on the Eyes of Experimental Animals. Progress in Clinical and Biological Research, 1989; 78: 312-68.
- Lee A. J., Mc Cluskey P. Clinical and differential effects of rostaglandin analogs in the management of raised intraocular pressure and ocular hypertantion. Clin Ophthalmol, 2010; 4: 741-64.
- Lima M. C., Paranhos A., Salim S. et al. Visually significant cystoid macular oedema in pseudophakic and aphakic patients with glaucoma receiving latanoprost. J. Glaucoma, 2000; 9(4): 317-21.
- Shrivastava A. Prostaglandin Analogs and Cataract Surgery. Cataract & Refractive Surgery Today, 2008; July: 75-7.
- Toris C. B., Gabelt B. T., Kaufman P. L. Update on the mechanism of action of topical prostaglandins for intraocular pressure reduction.Surv. Ophthalmol., 2008; 53(1): 107-120.
Supplementary files
