Diagnostic and prognostic value of procalcitonin blood level studies in patients with purulent-inflammatory diseases of the uterus and its appendages


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

The authors believe, that patients with purulent-inflammatory diseases of the uterus and its appendages, complicated widespread peritonitis, for values of blood procalcitonin level to 1.13 ng/mL can talk about abdominal sepsis without organ failure, at the level of 1.13-4.5 ng/mL should include developing organ failure 1-2 systems, that is, in this category of patients with high probability there is heavy abdominal sepsis with multiple organ failure laboratory level - disorders of the functioning of core indicators while maintaining homeostasis. If the levels of procalcitonin exceed 4.5 ng/ml, this indicates heavy abdominal sepsis with multiple organ failure in the progression multiple organ failure in multiple organ inconsistency. Reduction of procalcitonin in the postoperative period reflects a decrease in the body's inflammatory response, and reliable increase in the level of procalcitonin (and/or the absence of reduction) from the third day indicates the progression of the disease, which allows us to offer a method in monitoring and evaluating the effectiveness of the therapy.

Full Text

Restricted Access

About the authors

Biuzand Vazgenovich Arakelian

Saint Petersburg State Pediatric Medical University

Email: byuzand@mail.ru
MD, PhD, Dr Med Sci, Professor. Department of Children Gynecology and Female Reproductology, Faculty of Postgraduate Education

Nadezda Anatolyevna Kokhreidze

Saint Petersburg State Pediatric Medical University

Email: kokhreidze@mail.ru
MD, PhD, Associate Professor. Department of Children Gynecology and Female Reproductology, Faculty of Postgraduate Education

References

  1. Антонов А. Г., Байбарина Е. Н., Соколовская Ю. В. Объединенные диагностические критерии сепсиса у новорожденных. Вопросы гинекологии, акушерства и перинатологии. 2005; 4 (5-6): 113-5.
  2. Баранов А. А. Руководство по педиатрии (том Неонатология) / под ред. А. А. Баранова. М.: Медицина. 2007.
  3. Боженков Ю. Г., Коцовский М. И., Плисецкий А. В., Цеханович Н. Т., Пархоменко К. К. Хирургическая тактика при распространённом перитоните в неотложной гинекологии. Акуш. и гинек. 2001; 5: 51-2.
  4. Гринёв М. В., Громов М. И., Комраков В. Е. Хирургический сепсис. СПб. 2001.
  5. Краснопольский В. И., Буянова С. Н., Щукина Н. А. Гнойная гинекология. М.: МЕД-прессинформ. 2006.
  6. Серов В. Н., Панкова Е. О. Критерии прогноза осложнений и выбора основного метода лечения у больных с гнойно-воспалительными заболеваниями матки и придатков. Материалы VI Российского форума «Мать и дитя». 2004; 479-80.
  7. Шляпников С. А., Насер Н. Р., Аджамов Б. М. Проблема антибактериальной терапии в отделении реанимации и интенсивной терапии. Инфекции в хирургии. 2010; 8 (1): 47-8.
  8. Mullera B., Kenneth L. Becker. Procalcitonin: how a hormone became a marker and mediator of sepsis. Swiss med wkly. 2001; 131: 595-602.
  9. Simon L., Gauvin F., Devendra Amre K., Saint-Louis P., Lacroix J. Serum Procalcitonin and C-Reactive Protein Levels as Markers of Bacterial Infection: A Systematic Review and Meta-analysis. Clinical Infectious Diseases. 2004: 206-17.
  10. Vincent J. L., de Mendonza A., Cantraine F. et al. Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicentric, prospective study. Crit. Care Med. 1998; 26: 1793-800.
  11. Vincent J. L., Moreno R., Takala J., Willats S. The SOFA (sepsis - related organ failure assessment) score to describe organ dysfunction/failure. Intensive Care Med. 1996; 22: 707-10.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2015 Arakelian B.V., Kokhreidze N.A.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 69634 от 15.03.2021 г.


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies