Effective of antiviral therapy of HIV infection and intercurrent diseases in children

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Abstract


The study included 366 HIV-infected children (under-23) and 350 children with perinatal contact with HIV infection (R-75), consisting on the dispensary account in the Department of motherhood and childhood of the Saint Petersburg city AIDS center. The vast majority of children with perinatal HIV receive HAART (95.0%) with high efficacy (undetectable viral load, normalization of CD4 lymphocytes, the absence of clinical manifestations). In the structure of opportunistic viral infections (herpes, respiratory infections) 40.0%, bacterial (bronchitis, tonsillitis, pyoderma, pulmonary tuberculosis) - 28.6%, fungal infections (candidiasis mucous membranes of the oral cavity) and Pneumocystis pneumonia - 31.4%. Complex therapy (etiotropic, pathogenetic, symptomatic) acute respiratory viral infections in children with B-23 and R-75, allows us to achieve in the early stages (6 days treatment) of the regression of the main symptoms of acute respiratory diseases.

Vladimir N Timchenko

Author for correspondence.
timchenko220853@yandex.ru
St Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Russian Federation

MD, PhD, Dr Med Sci, Professor, Head, Department of Infectious Diseases in Children in the name of M. G. Danilevich

Elena B Yastrebova

elena_yastrebova@inbox.ru
I.P. Pavlov First St Petersburg State Medical University of the Ministry of Healthcare of the Russian Federation
Russian Federation

MD, PhD, Dr Med Sci, Associate Professor.

Oksana V Bulina

detinfection@mail.ru
St Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Russian Federation

MD, PhD, Associate Professor.

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