Anomalies of the Constitution and Tuberculosis Infection in Children

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Abstract


Phenotypical implications of genetic features are anomalies of the constitution or diathesis. A research objective children had an identification with a tuberculosis infection of occurrence of diathesis. 222 children aged from 1 year up to 14 years are examined: 106 children with active forms of tuberculosis; 54 children with residual post-tubercular changes; 62 children infected with MBT. Limfatiko-hypoplastic, allergic, neuroarthritic, exudative and catarral diathesis was taped. Children with limfatiko-hypoplastic (17.0 ± 3.7%) and neuroarthritic diathesis most often occur among patients with active tuberculosis (17.0 ± 3.7%), children with allergic diathesis are more rare (10.4 ± 3.0% of cases. The least favorable current of active forms of tuberculosis became perceptible at children with limfatiko-hypoplastic diathesis: the complicated forms of tuberculosis became perceptible at them in 27.8 ± 10.6% of cases. At patients with neuroarthritic diathesis the complicated forms developed less often - in 11.1 ± 7.4% of cases. Children with allergic diathesis transferred only uncomplicated forms of primary period of tuberculosis. At children without anomalies of the constitution the complicated current was observed often - in 27.6 ± 5.9% of cases. Frequency of occurrence of children with allergic diathesis is higher at patients with residual post-tubercular changes (29.6 ± 6.2%) and the infected MBT (33.8 ± 6.1%), than at patients with active tuberculosis (10.4 ± 3.0%). Existence of a certain anomaly of the constitution in many respects predetermines the course of a tuberculosis infection.


Iulia A Yarovaya

Author for correspondence.
julia_yarovaya@mail.ru
St Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Russian Federation, Saint Petersburg, Russia

MD, PhD, Associate Professor, Department of TB

Marina E Lozovskaya

lozovskaja-marina@rumbler.ru
St Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Russian Federation, Saint Petersburg, Russia

MD, PhD, Dr Med Sci, Professor, Head, Department of TB

Elena B Vasilieva

helenchern27@mail.ru
St Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Russian Federation, Saint Petersburg, Russia

MD, PhD, Associate Professor, Department of TB

Ludmila V Klochkova

lklochkova@yahoo.com
St Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Russian Federation, Saint Petersburg, Russia

MD, PhD, Associate Professor, Department of TB

Olga M Noskova

julia_yarovaya@mail.ru
Saint Petersburg State Healthcare Institution “Children’s City Infectious Diseases Hospital No 3”
Russian Federation, Saint Petersburg, Russia

Tuberculosis Department

Irina A Bikova

egorovairina88@mail.ru
Saint Petersburg State Healthcare Institution “Children’s City Infectious Diseases Hospital No 3”
Russian Federation, Saint Petersburg, Russia

Tuberculosis Department

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Copyright (c) 2017 Yarovaya I.A., Lozovskaya M.E., Vasilieva E.B., Klochkova L.V., Noskova O.M., Bikova I.A.

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