Menopausal disorders in obese women

Aim. To study menopausal disorders in women suffering from obesity.

Methods. The study included 165 women in physiological postmenopausal state. Women were divided into two groups: group 1 (study group) included 87 women with obesity, group 2 (control group) consisted of 78 women without obesity. With the use of modified menopausal index (the Kupperman index) the severity of climacteric disorders was assessed. Severity of neurovegetative, metabolic-endocrine and psychoemotional symptoms was assessed according to 4-point scale (from 0 to 3 points). The number of points in each group was summarized and a modified menopausal index was obtained.

Results. It was revealed that in women with obesity severe (in 24 females, 27.5%) and moderate (in 39 patients, 44.5%) climacteric syndrome was prevalent, in patients from the control group such forms were 1.5-2 times less frequent - in 11 (14.2%) and 28 (36.2%) patients, respectively. A deeper analysis of the entire symptom complex of climacteric syndrome revealed that severe and moderate forms of neurovegetative manifestations were 2 times more common in patients with obesity, in contrast to healthy women (in 7.8% and 4.5%, 21.5% and 12.3%, respectively). Severe forms of psychoemotional manifestations were also observed 2.6 times more often in women with obesity.

Conclusion. Severity of menopausal disorders depends on obesity presence, the data obtained demonstrated that, against the background of obesity, climacteric syndrome tends to have prolonged course with predominance of severe and moderate forms.