Ophthalmology Reports

Medical peer-reviewed quarterly journal published since 2008.


WEB: https://eco-vector.com/ 

Chief editor

professor Dmitriy V. Davydov, MD, Dr. Sci. (Medicine)
ORCID: 0000-0001-5506-6021 


Main publications of the journal are focused on key issues of modern ophthalmology: etiology and pathogenesis, epidemiology, clinical picture features, up-to-date methods of diagnosis, prevention, and treatment of eye diseases and of those of its adnexa.

The journal publishes original articles, scientific reviews, lectures, clinical case descriptions (presented by Russian and foreign authors), and informs about past congresses and conferences in Russia.

The journal is oriented toward practicing ophthalmologists, including ophthalmic surgeons, scientific and teaching staff of medical higher educational institutions, physicians in ophthalmology training, as well as for specialists of allied health specialties.

The journal’s mission:

  1. To integrate research results of Russian scientists and the rich clinical experience of practicing doctors in diagnosis, prevention, and treatment of eye diseases into the international scientific space; to be an international scientific platform for discussions and sharing experiences;
  2. To provide for ophthalmologists of the Russian Federation actual and high quality research and practice insights into most up-to-date treatment and prevention methods of eye diseases and of those of its adnexa.


  • in English, Russian, Chinese 
  • in hybrid access (subscription and Open Access with СС BY-NC-ND license)
  • with no obligatory APC for all authors


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"Ophtalmology Reports" — the new parallel title of the journal to be used in citations and references

Posted: 14.11.2022

The journal has changed its parallel title in English to "Ophtalmology Reports" to ensure the uniqueness of the name among scientific journals with similar research fields.

Editorial team ask the authors to use the parallel title "Ophthalmology Reports" when citing published articles to indicate the journal correctly, even if the cited articles were published in earlier issues of the journal. This will allow not to lose the citations of the journal and better identify references.

All articles' publication imprint are kept unchanged, including DOI. Changing the parallel title is not associated with changes in ISSN and eISSN (remained the same) and does not change the scientometric indicators of the journal, but is intended to eliminate incorrect citation counting, which may occur when there are several different journals with the same title.

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Current Issue

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Vol 15, No 4 (2022)

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Original researches

The effect of retinal perfusion on the bioelectric activity of the retina in full-thickness macular holes
Doktorova T.A., Suetov A.A., Boiko E.V., Sosnovskii S.V.

BACKGROUND: Information on retinal capillary perfusion in idiopathic full-thickness macular hole (FTMH) is limited, and there are no data on the possible effect of blood supply to individual areas and layers of the retina on their functional activity.

AIM: To study the relationship between vascular perfusion in the superficial and deep capillary plexuses (SCP and DCP) and the bioelectrical activity of the retina in full-thickness macular hole.

MATERIALS AND METHODS: Multifocal electroretinography (mfERG), optical coherence tomography (OCT), and OCT-angiography (OCTA) were performed in 18 eyes with FTMH and 10 intact eyes. In the projection of individual hexagons of the mfERG pattern, parameters of bioelectrical activity were compared with structural changes (hole, cystic changes), capillary density in the SCP and DCP.

RESULTS: In the FTMH group, the density of capillaries in the superficial capillary plexuses correlated with P1 implicit time in the R2 ring hexagons (R = –0.23, p < 0.05), in the hole zone and intraretinal cystic changes (R = –0.21 and R = –0.22, p < 0.05), P1 amplitude in the hole zone (R = 0.24, p < 0.05). In deep capillary plexuses, the capillary density correlated with N1 implicit time at the fixation point and the hole zone (R = –0.57 and R = –0.19, p < 0.05), P1 implicit time at the hole zone (R = –0.2, p < 0.05), P1 amplitude in the hexagons of the R2 and R3 rings (R = 0.46 and R = 0.44, p < 0.05), more pronounced in the hole zone and cystic changes (R = 0.54 and R = 0.29, p < 0.05).

CONCLUSIONS: There is a correlation between capillary perfusion in different layers of the retina and its bioelectrical activity in FTMH. A decrease in perfusion in the deep capillary plexus of the macula with a chronic macular hole may be a predictor of a low functional prognosis in the outcome of surgical treatment of FTMH.

Ophthalmology Reports. 2022;15(4):7-14
pages 7-14 views
Results of surgical treatment and rehabilitation of patients with post-traumatic subatrophy and anophthalmic syndrome in combination with bone deformities of the orbit
Davydov D.V., Baranova N.A.

BACKGROUND: Ocular prosthetics remains an important and actual task in the rehabilitation of patients with anophthalmos of various origins.

AIM: To increase the effectiveness of cosmetic prosthetics in patients at the formation of a primary and/or delayed supporting stump with simultaneous reconstructive procedures on the orbital bone structures.

MATERIALS AND METHODS: A retrospective analysis of patients with subatrophy and anophthalmos with deformities of the orbital walls was carried out. Results were analyzed according to the criteria for the severity of clinical signs — enophthalmos, deepening of the superior orbitopalpebral sulcus, prosthesis mobility.

RESULTS: 22 patients with orbital bone deformities were operated and examined; they underwent surgery on the orbital walls in combination with evisceration with posterior scleral pole resection, neurectomy and implantation of a spherical endoprosthesis (in modifications) in 12 patients and delayed stump plasty in 10 patients with anophthalmos. It was possible to eliminate enophthalmos in 18 patients, to correct the retraction of the upper eyelid on the prosthesis side in 19 patients, and to significantly increase the mobility of the prosthesis in 9 patients.

CONCLUSIONS: Carrying out a combined surgical procedure aimed at restoring a voluminous mobile primary or delayed supporting stump and eliminating the deformation of the orbital walls with restoring the lost volume creates conditions for optimal individual ocular prosthetics, significantly reduces prosthesis enophthalmos, increases its mobility and improves cosmetic results of rehabilitation.

Ophthalmology Reports. 2022;15(4):15-26
pages 15-26 views
Phacoemulsification in patients after previous implantation of a complete intrastromal ring into a corneal transplant
Sinitsyn M.V., Pozdeyeva N.A.

BACKGROUND: The MyoRing implantation into a corneal transplant can significantly compensate for irregular post-keratoplastic astigmatism. However, the cataract that occurs in this category of patients and the lack of information in the literature on its phacoemulsification and the calculation of a toric intraocular lens (tIOL) power in them determines the relevance of our study.

AIM: The aim of the study is to conduct a clinical and functional analysis of phacoemulsification in patients after previously performed implantation of a MyoRing into a corneal transplant.

MATERIALS AND METHODS: We operated on 21 patients (21 eyes) who had previously undergone the MyoRing implantation into a corneal transplant. According to keratotopography, all patients were diagnosed with a regular form of corneal astigmatism. All patients underwent phacoemulsification with tIOL implantation. When calculating the tIOL power, its diopter value was corrected depending on the average value of the corneal transplant keratometry according to the keratotopogram data. The observation period duration was 6 months.

RESULTS: One month after the procedure, there was an increase in uncorrected visual acuity by 0.2 ± 0.9 LogMAR, best corrected visual acuity by 0.3 ± 1.0 LogMAR, the spherical component of refraction — up to –0.4 ± 0.44 D, the cylindrical component of refraction — up to –0.62 ± 0.18 D, all of which did not change later on.

CONCLUSIONS: Phacoemulsification with tIOL implantation, with its power calculated taking into account an additional correction for its diopter value, is an effective, predictable and safe method of treating patients after previously performed MyoRing implantation into a penetrating corneal transplant.

Ophthalmology Reports. 2022;15(4):27-33
pages 27-33 views
Factors influencing the effectiveness of trabeculectomy: following materials of the City Multidisciplinary Hospital No. 2
Аntonova А.V., Nikolaenko V.P., Brzheskiy V.V., Vuks A.J.

BACKGROUND: Despite the ever-expanding arsenal of IOP-lowering surgeries, trabeculectomy remains the most common procedure amongst them. Therefore, the identification of factors reducing its effectiveness and potentially being able to change the surgical treatment plan is of particular importance.

AIM: To identify factors reducing trabeculectomy effectiveness.

MATERIALS AND METHODS: The study group consisted of 443 consecutively enrolled patients who were operated in 2016–2020 in Saint Petersburg City Multidisciplinary Hospital No. 2 for primary open-angle decompensated glaucoma and then observed for 6 to 24 months. Using statistical research methods, factors that significantly affected the impact of the procedure were identified.

RESULTS: The main predictors of trabeculectomy failure following the order of decreasing importance of established relations (p) were: loss of effectiveness of the preceding IOP-lowering procedure (р = 0.0001), dry eye syndrome (р = 0.013), number of drop instillations per day (р = 0.041), and excessive preservative load due to unnecessarily aggressive topical glaucoma treatment (р = 0.039). An obvious demonstration of excessive therapy is a simultaneous administration of four IOP-lowering medications. It also causes scarring of the procedure area, especially in patients previously operated for glaucoma. Null preservative load and prostaglandin monotherapy are associated with guaranteed “complete success” of trabeculectomy. Unlike the intensity of medical glaucoma treatment, its duration does not have such a significant impact on trabeculectomy outcomes (р = 0.270). Close to a significant one is the relationship between poor surgical outcomes and advanced stages of the disease (р = 0.052).

CONCLUSIONS: The main factors affecting the effectiveness of trabeculectomy were failure of the previous IOP-lowering surgeries; concomitant dry eye syndrome, arising or being aggravated by unduly intense and prolonged pharmacological effects on the eye surface; as well as delayed appliance for surgical IOP normalization at advanced disease stages.

Ophthalmology Reports. 2022;15(4):35-44
pages 35-44 views
Anti-angiogenic therapy in the treatment of diabetic macular edema in various variants of the vitreoretinal interface
Boiko E.V., Oskanov D.H., Panova I.E., Sosnovskii S.V., Berezin R.D.

BACKGROUND: Anti-angiogenic therapy for diabetic macular edema (DME), recognized as the “gold standard”, is not always effective. When compensating for the general somatic status, it is necessary to search for local causes of DME resistance to anti-angiogenic therapy.

AIM: To study the effectiveness and features of anti-angiogenic therapy for DME in normal and pathological vitreoretinal interface (VRI).

MATERIALS AND METHODS: Patients who received anti-angiogenic therapy for 12 months, in addition to the standard examination, underwent optical coherence tomography with an assessment of morphometric parameters and VRI.

RESULTS: In addition to the groups of normal and pathological VRI, a group of transformation from pathological to normal VRI was identified. Visual acuity increases with normal VRI, decreases with pathological. OCT scores decrease in both groups. In the transformation group, an increase in vision and a decrease in OCT parameters were observed only after VRI transformation.

CONCLUSION: The pathologic condition of the VRI reduces effectiveness of anti-angiogenic therapy for DME, except for 10% of cases in which VRI is transformed into normal within 5-6 months from the start of treatment. These data should be taken into account when choosing a treatment strategy for DME.

Ophthalmology Reports. 2022;15(4):45-52
pages 45-52 views

Experimental trials

The use of platelet-rich plasma and two-component autofibrin glue in treatment of experimental chronic persistent corneal erosion
Toloknova V.A., Gavriluk I.O., Churashov S.V., Kulikov A.N.

BACKGROUND: The use of platelet-rich plasma (PRP) and its modifications are a promising treatment method for chronic inflammatory diseases of the cornea.

AIM: To evaluate and compare the clinical and morphological features of the corneal regeneration during experimental chronic persistent corneal erosion with the use of PRP and two-component autofibrin glue (TAFG).

MATERIALS AND METHODS: The studies were conducted in 18 rabbits (36 eyes). After modeling chronic persistent corneal erosion, the animals of the 1st group were treated with TAFG; animals of the 2nd group — with instillations of PRP, animals of the 3rd group — with standard medical therapy.

RESULTS: By Day 14 of the experiment, the restoration of the transparency of the cornea, no erosion and new vessels in animals of the 1st and 2nd group were noted. This pattern persisted until Day 60. By Day 30 of the experiment, the presence of corneal clouding in optical zone, neovascularization over the whole cornea and an epithelial defect (3,85 [3,50; 4,47] %) in animals of the 3rd group were recorded. By Day 60, a complete epithelialization of the cornea was observed.

CONCLUSIONS: The use of PRP and TAFG allows reducing the time of corneal epithelialization by 2,5 times in conditions of experimental chronic persistent corneal erosion. There were no significant differences between the use of PRP (within 5 days) and TAFG, however, treatment with an adhesive composition is more convenient for both the doctor and the patient — a single use that does not require multiple use of expensive consumable materials.

Ophthalmology Reports. 2022;15(4):53-60
pages 53-60 views


Features of a well-timed macular hole closure related retinal regmatogenous detachment complicated by macular hole
Fayzrakhmanov R.R., Shishkin M.M., Larina E.A., Sekhina O.L., Vaganova E.E.

The literature review deals with the analysis of the timing and surgical techniques of macular hole closure in patients with retinal detachment complicated by macular hole. Modern concepts of treatment tactics for this disease, its efficacy are analyzed. Benefits and drawbacks of each of the discussed surgical treatment methods are specified.

Ophthalmology Reports. 2022;15(4):61-74
pages 61-74 views
Intermittent exotropia with convergence insufficiency — diagnostics, methods of invasive treatment
Stepanets I.R., Kulikov A.N., Koskin S.A., Kovalevskaya I.S.

The review analyzes most common injection and surgical methods of treatment of intermittent exotropia of convergence insufficiency: injections of botulinum toxin type A, injections of bupivacaine, bilateral recession of lateral rectus muscles with imposition of fixation sutures or without it (including “hemi-hang-back, no-noose technique”), recession of lateral rectus muscles according to Stellard, unilateral or bilateral resection of medial rectus muscle, a combination of resection with recession in one eye, the formation of a duplication of medial rectus muscle. The results before and after treatment are presented. The results of evaluating the effectiveness of invasive therapy in patients with exotropia with convergence insufficiency are summed up.

Ophthalmology Reports. 2022;15(4):75-83
pages 75-83 views

Case reports

Manifestations of uveitis of toxoplasmosis etiology after vaccination: clinical cases
Ionova O.G., Karetsky A.V., Hokkanen V.M., Zumbulidze N.G., Bagriantseva O.V.

Inflammatory diseases of the retina and choroid (chorioretinitis), including those of toxoplasmosis etiology usually occur against a background of decrease in immunity. We present two clinical cases of ocular inflammation at different times after the vaccination with “Sputnik V”. An analysis of the occurrence of ocular pathologic condition after vaccination to prevent coronavirus infection caused by the SARS-CoV-2 virus will help determine the criteria for prophylactic ophthalmological examination of patients before vaccination.

Ophthalmology Reports. 2022;15(4):85-91
pages 85-91 views

Organization of ophthalmic care

Surgery of age-related cataract: epidemiological nuances
Tyunina N.V., Gromakina E.V., Basova G.G., Mozes V.G.

AIM: To perform the analysis of the age composition of patients with a planned in-patient surgical procedure — “cataract phacoemulsification”.

MATERIALS AND METHODS: Three cohorts of patients diagnosed with “age-related senile cataract” were analyzed for the periods 2000–2003 (n = 6737), 2007–2009 (n = 13,015), and 2015–2017 (n = 1363) on the basis of “age at the time of planned surgery” in the ophthalmology hospital “S.V. Belyaev Kuzbass Clinical Hospital”. Persons with a diagnosis of “congenital, complicated, traumatic cataract” and persons operated as out-patients were excluded from all samples.

RESULTS: At the first stage, the average age of patients at the time of surgical treatment of patients diagnosed with senile cataract was calculated. At the second stage, the age of operated patients was analyzed by decades of human life. At the third stage, the assessment of the judgment about the “rejuvenation” of the age of operated patients with incipient cataract according to professional indications was carried out.

CONCLUSIONS: The average age of patients operated on with senile cataract during a fifteen-year period is a stable value in the range of 66–68 years. In the dynamics from 2000 to 2017, there was a redistribution of patients with senile cataract within the cohort by age. Rejuvenation of the age composition of persons with cataracts occurred due to an increase in patients aged 51–60 years by 2 times and a decrease in patients aged 71–80 years by 1.6 times. The proportion of patients undergoing surgical treatment for senile cataract in a hospital setting with visual acuity of 0.1 or less is stable and amounts to 78.4–87.5 %.

Ophthalmology Reports. 2022;15(4):93-98
pages 93-98 views


The jubilee of Elena Ivanovna Ustinova
Beldovskaya N.Y., Lisochkina A.B.

The article is concerned with the life journey of the phtisioophthamologist Professor Elena Ivanovna Ustinova who celebrated her 95th anniversary on October 19th, 2022

Ophthalmology Reports. 2022;15(4):99-102
pages 99-102 views

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