Application of quantitative multiplex real-time polymerase chain reaction for identification of causative agents of urinary tract infections in pregnancy


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Abstract

Urinary tract infections (UTIs) represent the most common bacterial infections and often complicate pregnancy. UTIs in pregnancy are classified by site of bacterial proliferation as follows: asymptomatic bacteriuria, cystitis, pyelonephritis. Screening for asymptomatic bacteriuria is a standard of obstetrical care and is included in most international guidelines. The urine microbiologic culture is considered the gold standard for laboratory diagnosis of UTIs. Molecular methods enable to rapidly detect, identify and quantitate causative agents of UTIs in urine and are effective alternative to traditional bacteriological methods.

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About the authors

Tatyana Alekseyevna Khusnutdinova

D. O. Ott Research Institute of Obstetrics and Gynecology RAMS

Email: HusnutdinovaT@yandex.ru
Researcher, Laboratory of Microbiology

Yuliya Anatolyevna Savochkina

Central Research Institute of Epidemiology

Email: savochkina@pcr.ru
PhD, Senior Researcher, Laboratory of Molecular Diagnostics and Epidemiology of Reproductive Tract Infections, Department of Mo-lecular Diagnostics and Epidemiology

Aleksandr Yevgenyevich Gushchin

Central Research Institute of Epidemiology

Email: aguschin@pcr.ru
PhD, Head of the Laboratory of Molecular Diagnostics and Epidemiology of Reproductive Tract Infections, Department of Molecular Diagnostics and Epidemiology

Yelena Vasilyevna Shipitsyna

D. O. Ott Research Institute of Obstetrics and Gynecology RAMS

Email: shipitsyna@inbox.ru
PhD, Senior Researcher, Laboratory of Microbiology

Alevtina Mikhailovna Savicheva

D. O. Ott Research Institute of Obstetrics and Gynecology RAMS

Email: savitcheva@mail.ru
MD, PhD, Dr Med Sci, Professor, Laboratory of Microbiology

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Copyright (c) 2014 Khusnutdinova T.A., Savochkina Y.A., Gushchin A.Y., Shipitsyna Y.V., Savicheva A.M.

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