Voenno-medicinskij žurnalVoenno-medicinskij žurnal0026-9050Eco-Vector7428810.17816/RMMJ74288Research ArticleOur experience of the clinical use of DesfluraneBliznovA. A-ZavarzinA. Yuaadk72@mail.ruUntuF. I-StetsV. V-1512201433512293101072021Copyright © 2014, Eco-Vector2014Despite the widespread use of inhalational anaesthetics in modern medical practice it is still unable to create an «ideal» anesthetic, which meets the following requirements - maximum performance, security, and manageability. Desflurane is an inhalational anaesthetic, which first appeared on Russian market in 2013, according to the specifications meet the above-mentioned requirements. The results of the use of Desflurane during anaesthesia in 157 patients of the Cancer Department and Department of Oral and Maxillofacial Surgery at the Burdenko Main Military Clinical Hospital are given. The main advantages are the rapid achievement of Desflurane required depth of anaesthesia, minimal effects on the cardiovascular system, good handling, fast and safe awakening of the patient after surgery, which can make it «anaesthetic of choice» for long surgical procedures and outpatient surgery.anesthesiologyinhalational anaesthetic Desfluranesolubility in bloodmanageability and the depth of anaesthesiacardiovascular system«one day» surgeryанестезиологияингаляционные анестетикидесфлуранрастворимость ингаляционного анестетика в кровиуправляемость и глубина анестезиисердечно-сосудистая системахирургия «одного дня»[Arain S.R., Shankar H., Ebert T.J. Desflurane enhances reactivity during the use of the laryngeal mask airway // Anesthesiology. - 2005. - Vol. 103, N 3. - P. 495-499.][Golembiewski J. Economic considerations in the use of inhaled anesthetic agents // Am. J. Health-Syst. Pharm. - 2010. - Vol. 67, N 8. -P. 9-12.][Kapoor M.C., Vakamudi M. Desflurane revisited // J. Anaesthesiol. Clin. Pharmacol. - 2012. - Vol. 28, N 31. - P. 92-100.][Klock P.A., Czeslick E.G., Klafta J.M. et al. The effect of sevoflurane and desflurane on upper airway reactivity // Anesthesiology. - 2001. -Vol. 94, N 6. - P. 963-967.][Magni G., La Rosa I., Melillo G. et al. A Comparison Between Sevoflurane and Desflurane Anesthesia in Patients Undergoing Craniotomy for Supratentorial Intracranial Surgery // Anesth. Analg. - 2009. - Vol. 109, N 2. -P. 567-571.][Royse C.F., Andrews D.T., Newman S.N. The influence of propofol or desflurane on postoperative cognitive dysfunction in patients undergoing coronary artery bypass surgery // Anaesthesia. -2011. - Vol. 66, N 3. - P. 455-464.][Weinberg L., Story D., Nam J., McNicols L. Pharmacoeconomics of inhalational anesthetic agents: an 11-year retrospective analysis // Anaesth. Intensive Care. - 2010. - Vol. 38, N 5. -P. 849-854.][White P.F., Tang J., Wender R.H. et al. Desflurane versus sevoflurane for maintenance of outpatient anesthesia: the effect on early versus late recovery and perioperative coughing // Anesth. Analg. - 2009. - Vol. 109, N 2. - P. 387-393.]