Voenno-medicinskij žurnalVoenno-medicinskij žurnal0026-9050Eco-Vector8241010.17816/RMMJ82410Research ArticleAssessing the relationship of mineral metabolism and bone metabolism in diseases of the thyroid glandAntonovP. F-SitnikovO. Vsitnikov@skkmorf-sevkav.ruPavlovA. V-CherkashinaL. D-KurkinaO. F-ZaikovaL. N-YurkovaG. P-Health-resort complex «North Caucasus» MD RF«The health-resort complex «North Caucasus» MD RF150820203418687005102021Copyright © 2020, Eco-Vector2020The effect of thyroid hormone deficiency on indicators of calcium - phosphorus metabolism, biochemical markers of bone metabolism in women of reproductive age (n=37) with primary hypothyroidism, depending on the characteristics of its course, was evaluated. In women with hypothyroidism without treatment, a slowdown in both bone resorption and bone formation is revealed due to a decrease in bone metabolism. In patients with primary hypothyroidism receiving hormone replacement therapy, increased bone resorption is detected. The most evident violations of bone metabolism in patients with hypothyroidism are observed with prolonged replacement therapy with thyroid hormones (over seven years) and with a history of thyrotoxicosis, as well as with a low initial peak bone mass.osteoporosishypothyroidismcalcium-phosphorus metabolismbone metabolismhormone replacement therapyостеопорозгипотиреозкальций-фосфорный обменкостный метаболизмзаместительная гормональная терапия[Верткин А.Л., Наумов А.В. Остеопороз: Руководство для практических врачей. - М.: Эксмо-Пресс, 2015. - 272 с.][Ушаков А.В. Анализ крови при заболеваниях щитовидной железы. - М.: Клиника доктора А.В.Ушакова, 2016. - 272 с.][Фадеев В.В., Ванушко В.Э. Постоперационный гипотиреоз и профилактика рецидивов заболеваний щитовидной железы. - М.: Видар-М, 2011. - 70 с.][Холодова Е.А. Клиническая эндокринология. - М.: Мед. информ. агентство, 2011. - 736 с.]