Email this article Efficacy of anti-inflammatory treatment with benacort of patients with chronic obstructive pulmonary disease in exacerbation
- Authors: Kolesnikov VV1, Korolchuk IS1
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Affiliations:
- Issue: Vol 78, No 1 (2003)
- Pages: 55-58
- Section: Editorial
- URL: https://ter-arkhiv.ru/0040-3660/article/view/29293
- ID: 29293
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Abstract
Aim. To determine a course and prognostic effectiveness of corticosteroid therapy of chronic obstructive
pulmonary disease (COPD).
Material and methods. Long-term therapy with broncholytics (berodual) and benacort was given to
25 patients in non-infectious exacerbation, 20 patients received broncholitics of 45 COPD patients
with mild and moderate ventilation disorders. Follow-up lasted for 2.5 years. Treatment effectiveness
was judged by clinical indices, external respiration function, parameters of systemic immunity, cyto-
gram of induced sputum and concentration of inflammatory markers in the sputum.
Results. An immediate effect of two-month therapy with benacort of COPD exacerbations manifested
with positive clinical dynamics and relief of endobronchial inflammation. Prognostic efficacy - with a
significant reduction of the frequency of COPD exacerbations and of their mean duration more than
3-fold.
Conclusion. The results of long-term follow-up support validity of inhalation corticosteroids use for
eradication and prevention of noninfectious exacerbations of COPD.
pulmonary disease (COPD).
Material and methods. Long-term therapy with broncholytics (berodual) and benacort was given to
25 patients in non-infectious exacerbation, 20 patients received broncholitics of 45 COPD patients
with mild and moderate ventilation disorders. Follow-up lasted for 2.5 years. Treatment effectiveness
was judged by clinical indices, external respiration function, parameters of systemic immunity, cyto-
gram of induced sputum and concentration of inflammatory markers in the sputum.
Results. An immediate effect of two-month therapy with benacort of COPD exacerbations manifested
with positive clinical dynamics and relief of endobronchial inflammation. Prognostic efficacy - with a
significant reduction of the frequency of COPD exacerbations and of their mean duration more than
3-fold.
Conclusion. The results of long-term follow-up support validity of inhalation corticosteroids use for
eradication and prevention of noninfectious exacerbations of COPD.
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