Alcohol consumption and its link withcardiovascular mortality in 40-59 year old males (data of a21.5 year prospective study)

Abstract


Aim. To study contribution of alcohol consumption (AC) to mortality of coronary heart disease
(CHD), cerebral stroke (CS), cardiovascular diseases (CVD), overall mortality (OM) in a random
population of working males.
Material and methods. The results are available of a 21.5 year cohort study of mortality in a random
population of 7815 male citizens of Moscow and St-Petersburg aged 40-59 years.
Results. The attributive risk of AC for mortality of CHD, CS, CVD and ОМ was 16.6, 14.8, 7.7and
11.9%, respectively. The lowest relative risk to die of CHD, CVD and OM among the cohort studied
was observed in males taking alcohol 168.0 ml per week maximum.
Conclusion. It is necessary to approach differentially to assessment of AC effects on development of
many diseases and further investigations are needed to reveal fine mechanisms of action of different
alcohol drinks on human organism.

About the authors

A L Alexandri

V V Konstantinov

A D Deev

A V Kapustina

D B Shestov

References

  1. Милле Ф., Школьников В. М., Эртриш В. и др. Современные тенденции смертности по причинам смертности в России 1965-1994. В кн.: Эпидемиологический кризис в странах бывшего СССР: INED; 1996; т. 2: 137 стр.
  2. Menotti A., Keys A., Blackburn H. et al. Comparison of multivariate predictive power of major risk factor for coronary heart disease in different countries: results from eight nations of theseven countries study, 25-year follow-up. Cardiovasc. Risk 1996; 3 (I): 69-75.
  3. Оганов Р. Г. Смертность от сердечно-сосудистых заболеваний в России и некоторые влияющие на нее факторы. Кардиология 1994; 3-4: 83-84.
  4. Александры А. Л. Связь потребления алкоголя с уровнем артериального давления и ишемической болезнью сердца у мужчин 20-59 лет. (Эпидемиологическое исследование): Автореф. дис.канд. мед. наук. М.; 1997.
  5. Немцов А. В. Алкогольная ситуация в России. М.; 1995.
  6. Кошкина Е. А., Паронян И. Д. Павловская Н. И. Оценка алкогольной ситуации в России. Рус. мед. журн. 1996; 3 (7): 421-424.
  7. Бельченко Д. И., Капустин А. В., Калинин М. Н. и др. Об атерогенности изменений липидного обмена, вызванных алкоголем. Кардиология 1983; 23 (2): 89-93.
  8. Лисицин Ю. П. Алкоголь - фактор риска. Тер. арх. 1985; 57 (12): 3-8.
  9. Bottiger L. Alcohol and diseases. Acta Med. Scand. 1988; 223: 97-99.
  10. Калинина А. М., Чазова Л. В. Прогностическая значимость поведенческих привычек (курения, употребления алкоголя, двигательной активности) в популяции мужчин 40-59 лет г. Москвы. Тер. арх. 1991; 1: 20-24.
  11. Пауков В. С, Беляева Н. Ю., Воронина Т. М. Алкоголизм и алкогольная болезнь. Там же 2001; 73 (2): 65-67.
  12. Holman С. D. I. Ought low alcohol intake to be promoted for health reasons? Roy. Soc. Med. 1996; 89: 123-129.
  13. Перова Н. В., Бубнова М. Г., Озерова И. Н. и др. Как влияет ежедневное употребление малых доз алкоголя на систему транспорта холестерина. Рос. кардиол. журн. 2000; 25 (5): 23-28.
  14. Pirwitz М. /., Lange R. A., Willard Т. Е. et al. Effects of intravenous ethanol on diameter of epicardial coronary arteries.Am. J. Cardiol. 1995; 75 (1): 77-82.
  15. Gaziano J. M., Buring J. E., Breslow T. L. et al. Moderate alcohol intake, increased levels of high density lipoprotein and subtractions and decreased risk of myocardial infarction. N.Engl. J. Med. 1993; 329: 1829-1834.
  16. Kelback H. Acute effects of alcohol and food intake on cardiac performance. Progr. Cardiovasc. Dis. 1990; 32 (5): 347-364.
  17. Shaper A. G. Alcohol and mortality: a review of prospective studies. Br. J. Addict. 1990; 85: 837-847.
  18. Shaper A. G. Alcohol and sudden cardiac death. Br. Heart J. 1992; 68: 443-448.
  19. Puddey L. В., Parker M. L., Beilin T. et al. Effects of alcohol and caloric restrictions on blood pressure and serum lipids in overweight men. Hypertension 1992; 20: 533-541.
  20. Kovar J., Korberova R., Poledne R. Alcohol consumption ef- fects on postprandial changes in triglyceride transporting lipoproteins. In: Abstracts Book of XII International Symposium Atheroscleros, Stockholm; 2000. 145.
  21. Kitner S. J., Garcia-Palmieri M. R., Costas R. et al. Alcohol and coronary artery disease in Puerto Rico. Am. J. Epidemiol. 1986; 124: 481-489.
  22. Kono S., Ikeda M., Tocudome S. et al. Alcohol and mortality: a cohort study of male Japanese physicians. Int. J. Epidemiol. 1986; 15 (3): 527-532.
  23. Fehily A. M., Yarnell J. W., Sweetnam P. M. et al. Diet and incident ischaemic heart diseases: the Caerphilly study. Br. J. Nutr. 1993: 69: 303-314.
  24. Salonen J. Т., Puska P., Nissinen A. Intake of spirits and beer and risk of myocardial infarction of healthy middle-age popu lation - longitudinal study in Eastern Finland. J. Chron. Dis. 1983; 36 (7): 533.
  25. Dole R., Peto R., Hall E. et al. Mortality in relation to consumption of alcohol: 13 years observations on male British doctors. Br. Med. J. 1994; 309: 911-918.
  26. Ueshima H., Mikawa K., Baba S. et al. Effect of reduced alcohol consumption on blood pressure in untreated hypertensive men. Hypertension 1993; 21: 248-252.
  27. Henneken С H., Willett W. W., Rosner D. et al. Effects of beer, wine, and liquor on coronary death. J. A. M. A. 1979; 242(8): 1973-1974.
  28. Criqui M. N., Ringel B. L. Does diet of alcohol explain the French paradox? Lancet 1994; 344: 1719-1723.
  29. Rimm E. В., Giovannucci E. L., Willett W. С et al. Prospective study of alcohol consumption and risk of coronary disease in men. Ibid. 1991; 338: 464-468.
  30. Cullen K. J., Knuiman M. W., Ward N. J. Alcohol and mortalty in Busselton, Western Australia. Am. J. Epidemiol. 1993; 136: 242-248.
  31. Шальнова С. А. Факторы риска сердечно-сосудистых заболеваний и показатели ожидаемой продолжительности жизни населения России: Автореф. дис. д-ра мед. наук. М.; 1999.
  32. Wannamethee G., Shaper A. G. Alcohol and sudden death. Br.Heart J. 1992; 68: 443-448.
  33. Djousse L., Pankov J. S., Arnett D. K. et al. Alcohol consump tion and plasminogen activator inhibitor type 1: The National Heart, Lung, and Blood Institute Family Heart Study. Am.Heart J. 2000; 139 (4): 704-709.
  34. Mukamal K. J., Jadhav P. P., D'Agostino R. B. et al. Alcohol consumption and hemostatic factors. Analysis of the Framingham offspring cohort. Circulation 2001; 104: 1367-1373.
  35. Pohorecky L. A. Interaction of alcohol and stress at the cardi vascular level. Alcohol 1990; 7: 537-546.
  36. Djousse L., Levy D., Murabito J. M. et al. Alcohol consumption and risk of intermittent claudication in the Framingham heart study. Circulation 2000; 102 (25): 3092-3097.
  37. Ajani U. A., Gaziano J. M., Lotufo P. A. et al. Alcohol consumption and risk of coronary heart disease by diabetes status. Ibid. (5): 500-505.
  38. Frankel E. M., Ranner J., German J. B. et al. Inhibition of oxidation of human low density lipoprotein by phenolic substances in red wine. Lancet 1993; 341: 454-457.
  39. Whitehead T. P., Robinson D., Allaway S. et al. Effect of red wine ingestion on the antioxidant capacity of serum. Clin. Chem. 1995; 41: 32-35.
  40. Blanco-Colio L. M., Valderrama M., Alvarez-Sala L. A. et al. Red wine intake prevent nuclear factor-кВ activation in peripheral blood mononuclear cells of healthy volunteers during postprandial Iipemia. Circulation 2000; 102 (9): 1020-1026.
  41. Farchi G., Fidanza FL, Gianpaoli S. et al. Alcohol and survival in the Italian rural cohorts of seven countries study. Int. J. Epidemiol. 2000; 29 (4): 667-671.
  42. Gronback M. D., Sorenson T. J., Blecker If. et al. Mortality associated with moderate intakes of wine, beer, spirits. Br. Med. J. 1995; 310: 1165-1169.

Statistics

Views

Abstract - 8

Cited-By


Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
 

Address of the Editorial Office:

  • Novij Zykovskij proezd, 3, 40, Moscow, 125167

Correspondence address:

  • Novoslobodskaya str 31c4., Moscow, 127005, Russian Federation

Managing Editor:

 

© 2018 "Consilium Medicum" Publishing house

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies