Morphofunctional changes in the small intestine in patients with chronic cardiac failure
- Authors: Arutyunov GP1, Kostyukevich OI1, Serov RA1, Rylova AK1, Korsunskaya MI1, Balanina NO1, Rylova NV1, Pokrovsky Y.A1, Voevodina NY.1
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- Issue: Vol 79, No 2 (2004)
- Pages: 40-44
- Section: Editorial
- Submitted: 09.04.2020
- Published: 15.02.2004
- URL: https://ter-arkhiv.ru/0040-3660/article/view/29758
- ID: 29758
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Abstract
Results. A rise in collagen content in the small intestine correlated with severity of CCF. In patients free of CCF relative area of collagen averaged 12.8%, in CCF FC I-II - 16.5%, in CCF FCIIIIV with cachexia - 32.4%. Greater fibrosis of the small intestine corresponded to greater malabsorption. A 3-fold increase in collagen area led to a 2-3-fold growth in protein and fat loss with feces. In CCF, LBM was subnormal while body mass reduction correlated with relative collagen area. Conclusion. Morphofunctional changes of the small intestine developing in parallel with CCF severity lead to a significant loss in basic nutrients, regression of LBM and development of protein-energy insufficiency in patients with CCF.
About the authors
G P Arutyunov
O I Kostyukevich
R A Serov
A K Rylova
M I Korsunskaya
N O Balanina
N V Rylova
Yu A Pokrovsky
N Yu Voevodina