Hypogonadism and cardiovascular diseases in men


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Abstract

The article analyses correlation between low levels of sex hormones in men (male hypogonadism) and cardiovascular diseases. It was believed for a long time that androgens have adverse effect on cardiovascular system. It is shown that, on the contrary, hypogonadism indirectly raises the risk of cardiovascular diseases via various components of metabolic syndrome. Moreover, correction of male hypogonadism with testosterone preparations may have a positive effect on risk factors of vascular complications including fat reduction , normalization of blood pressure, correction of dyslipidemia. Pharmacologically, testosterone undecanoate for intramuscular injections (nebido) is a good form. This drug can provide a stable physiological testosterone level for about 12 weeks after injection.

About the authors

Safail Ogly Gamidov

Email: docand@rambler.ru

Oleg Khalitovich Tazhetdinov

Vyacheslav Vasil'evich Iremashvili

S I Gamidov

N.I. Pirogov Russian State Medical University, Moscow; I.M. Sechenov First Moscow State Medical University

N.I. Pirogov Russian State Medical University, Moscow; I.M. Sechenov First Moscow State Medical University

O Kh Tazhetdinov

N.I. Pirogov Russian State Medical University, Moscow

N.I. Pirogov Russian State Medical University, Moscow

V V Iremashvili

N.I. Pirogov Russian State Medical University, Moscow

N.I. Pirogov Russian State Medical University, Moscow

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