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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Advances in Current Biology</journal-id><journal-title-group><journal-title xml:lang="en">Advances in Current Biology</journal-title><trans-title-group xml:lang="ru"><trans-title>Успехи современной биологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0042-1324</issn><issn publication-format="electronic">3034-6347</issn><publisher><publisher-name xml:lang="en">The Russian Academy of Sciences</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">687230</article-id><article-id pub-id-type="doi">10.31857/S0042132425020037</article-id><article-id pub-id-type="edn">GDBHAY</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Domestic goat as a promising animal model for high-level brain function research</article-title><trans-title-group xml:lang="ru"><trans-title>Коза домашняя как перспективный модельный объект для исследования высшей нервной деятельности</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gladysh</surname><given-names>N. S.</given-names></name><name xml:lang="ru"><surname>Гладыш</surname><given-names>Н. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>natalyagladish@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Piskunov</surname><given-names>A. K.</given-names></name><name xml:lang="ru"><surname>Пискунов</surname><given-names>А. К.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>natalyagladish@gmail.com</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Stolpovsky</surname><given-names>Yu. A.</given-names></name><name xml:lang="ru"><surname>Столповский</surname><given-names>Ю. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>natalyagladish@gmail.com</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Samsonova</surname><given-names>Zh. V.</given-names></name><name xml:lang="ru"><surname>Самсонова</surname><given-names>Ж. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>natalyagladish@gmail.com</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Saushkin</surname><given-names>N. Yu.</given-names></name><name xml:lang="ru"><surname>Саушкин</surname><given-names>Н. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>natalyagladish@gmail.com</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Volodin</surname><given-names>V. V.</given-names></name><name xml:lang="ru"><surname>Володин</surname><given-names>В. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>natalyagladish@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kudryavtsev</surname><given-names>A. A.</given-names></name><name xml:lang="ru"><surname>Кудрявцев</surname><given-names>А. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>natalyagladish@gmail.com</email><xref ref-type="aff" rid="aff4"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kudryavtseva</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Кудрявцева</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>natalyagladish@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Engelhardt Institute of Molecular Biology, Russian Academy of Sciences</institution></aff><aff><institution xml:lang="ru">Институт молекулярной биологии им. В.А. Энгельгардта РАН</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Vavilov Institute of General Genetics, Russian Academy of Sciences</institution></aff><aff><institution xml:lang="ru">Институт общей генетики им. Н.И. Вавилова РАН</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Lomonosov Moscow State University</institution></aff><aff><institution xml:lang="ru">Московский государственный университет им. М.В. Ломоносова</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">Razumovsky Moscow State University of Technologies and Management (First Cossack University)</institution></aff><aff><institution xml:lang="ru">Московский государственный университет технологий и управления им. К.Г. Разумовского (Первый казачий университет)</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2025-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2025</year></pub-date><volume>145</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>123</fpage><lpage>130</lpage><history><date date-type="received" iso-8601-date="2025-07-10"><day>10</day><month>07</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-07-10"><day>10</day><month>07</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Russian Academy of Sciences</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Российская академия наук</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Russian Academy of Sciences</copyright-holder><copyright-holder xml:lang="ru">Российская академия наук</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/0042-1324/article/view/687230">https://journals.eco-vector.com/0042-1324/article/view/687230</self-uri><abstract xml:lang="en"><p>Goats were the first animals to undergo domestication. Despite the fact that they are bred across much of the world, they have not yet been widely used as a research model. However, goats have remarkable cognitive abilities, complex and varied social behaviour, and due to their size and low maintenance requirements, they may serve as a promising model for studying neurological conditions, especially neurodegenerative diseases. This review focuses on current research into the central nervous system of goats, as well as their behaviour and cognitive abilities.</p></abstract><trans-abstract xml:lang="ru"><p>Козы стали первыми животными, которые подверглись одомашниванию. Несмотря на то, что их разводят практически во всем мире, среди исследователей они пока не нашли признания в качестве модели для исследований. Однако козы обладают незаурядными когнитивными способностями, интересным и многогранным социальным поведением, а также благодаря размеру и нетребовательности к условиям содержания могут стать перспективным объектом для исследований неврологических состояний организма, а также ассоциированных с ними изменений в поведении. Данный обзор посвящен рассмотрению актуальных исследований центральной нервной системы коз, а также их поведения и когнитивных способностей.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Capra hircus</kwd><kwd>domestic goat</kwd><kwd>higher nervous activity</kwd><kwd>behaviour</kwd><kwd>neurodegenerative diseases</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Capra hircus</kwd><kwd>домашняя коза</kwd><kwd>высшая нервная деятельность</kwd><kwd>поведение</kwd></kwd-group><funding-group><award-group><funding-source><institution-wrap><institution xml:lang="ru">Российский научный фонд</institution></institution-wrap><institution-wrap><institution xml:lang="en">Russian Science Foundation</institution></institution-wrap></funding-source><award-id>24-14-00456</award-id></award-group><award-group><funding-source><institution-wrap><institution xml:lang="ru">Российский научный фонд</institution></institution-wrap><institution-wrap><institution xml:lang="en">Russian Science Foundation</institution></institution-wrap></funding-source><award-id>2276-10053</award-id></award-group></funding-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Agarwal P., Kumar M., Kumar K. et al. 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