<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Advances in Current Biology</journal-id><journal-title-group><journal-title xml:lang="en">Advances in Current Biology</journal-title><trans-title-group xml:lang="ru"><trans-title>Успехи современной биологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0042-1324</issn><issn publication-format="electronic">3034-6347</issn><publisher><publisher-name xml:lang="en">The Russian Academy of Sciences</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">687242</article-id><article-id pub-id-type="doi">10.31857/S0042132425020097</article-id><article-id pub-id-type="edn">GEFAAL</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>DISCUSSIONS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ДИСКУССИИ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">On the theory of increasing complexity by professor A.P. Kozlov, published in a series of papers in 2024</article-title><trans-title-group xml:lang="ru"><trans-title>О теории увеличения сложности профессора А.П. Козлова, опубликованной в серии работ в 2024 г.</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Zaborovsky</surname><given-names>V. S.</given-names></name><name xml:lang="ru"><surname>Заборовский</surname><given-names>В. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>vlad2tu@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Peter the Great St. Petersburg Polytechnic University</institution></aff><aff><institution xml:lang="ru">Санкт-Петербургский политехнический университет Петра Великого</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2025-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2025</year></pub-date><volume>145</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>169</fpage><lpage>172</lpage><history><date date-type="received" iso-8601-date="2025-07-10"><day>10</day><month>07</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-07-10"><day>10</day><month>07</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Russian Academy of Sciences</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Российская академия наук</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Russian Academy of Sciences</copyright-holder><copyright-holder xml:lang="ru">Российская академия наук</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/0042-1324/article/view/687242">https://journals.eco-vector.com/0042-1324/article/view/687242</self-uri><abstract xml:lang="en"><p>A series of works by Professor A.P. Kozlov, published in the journals “Advances in Current Biology” and “Paleontological Journal” in 2024, is devoted to fundamental issues of the evolutionary development of living organisms, the analysis of which is based on the role of inherited tumors as a natural mechanism for the formation of evolutionarily new tissues and organs. The study of this mechanism is the basis for the theory of <italic>carcino-evo-devo</italic>, which, according to the author, explains the process of increasing the biological complexity of living organisms. In this review the conclusions from the new chapters of A.P. Kozlov’s theory concerning the increasing complexity of living organisms from the standpoint of computer science and information technology are analyzed.</p></abstract><trans-abstract xml:lang="ru"><p>Серия работ профессора А.П. Козлова, опубликованных в журналах “Успехи современной биологии” и “Палеонтологический журнал” в 2024 г., посвящена фундаментальным вопросам эволюционного развития живых организмов, анализ которых основан на роли наследственных опухолей как естественных механизмов формирования эволюционно новых тканей и органов. Изучение этого механизма лежит в основе теории <italic>carcino-evo-devo</italic>, которая, по мнению автора, объясняет процесс увеличения биологической сложности живых организмов. В обзоре проанализированы выводы из новых глав теории А.П. Козлова, касающиеся возрастающей сложности живых организмов, с точки зрения информатики и информационных технологий.</p></trans-abstract><kwd-group xml:lang="en"><kwd>evolutionary theory</kwd><kwd>hereditary tumors</kwd><kwd>carcino-evo-devo</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>эволюционная теория</kwd><kwd>наследственные опухоли</kwd><kwd>carcino-evo-devo</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Козлов А.П. Теория эволюционной роли наследуемых опухолей (carcino-evo-devo): история развития и современное состояние. Часть 1. От общих принципов к гипотезе и от гипотезы к концепции // Успехи соврем. биол. 2024а. Т. 144 (3). С. 249–264. https://doi.org/10.31857/S0042132424030013</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Козлов А.П. Теория эволюционной роли наследуемых опухолей (carcino-evo-devo): история развития и современное состояние. Часть 2. Становление теории в книге “Evolution by Tumor Neofunctionalization” // Успехи соврем. биол. 2024б. Т. 144 (4). С. 364–373. https://doi.org/10.31857/S0042132424040011</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Козлов А.П. Теория эволюционной роли наследуемых опухолей (carcino-evo-devo): история развития и современное состояние. Часть 3. Современное состояние теории carcino-evo-devo и ее взаимоотношения с другими биологическими науками // Успехи соврем. биол. 2024в. Т. 144 (4). С. 374–401. https://doi.org/10.31857/S0042132424040024</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Козлов А.П. Теория эволюционной роли наследуемых опухолей (carcino-evo-devo): история развития и современное состояние. Часть 4. Общая теория увеличения биологической сложности в прогрессивной эволюции // Успехи соврем. биол. 2024г. Т. 144 (5). С. 478–487. https://doi.org/10.31857/S0042132424050011</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Crick F. Central dogma of molecular biology // Nature. 1970. V. 226. P. 561–563. https://doi.org/10.1038/227561a0, PMID: 4913914</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Kozlov A.P. Evolution of living organisms as a multilevel process // J. Theor. Biol. 1979. V. 81 (1). P. 1–17.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Kozlov A.P. The role of heritable tumors in evolution of development: a new theory of carcino-evo-devo // Acta Naturae. 2019. V. 11 (4). P. 65–72. https://doi.org/10.32607/20758251-2019-11-4-65-72</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Kozlov A.P. Biological computation and compatibility search in the possibility space as the mechanism of complexity increase during progressive evolution // Evol. Bioinform. 2022a. V. 18. P. 1–5. https://doi:10.1177/11769343221110654</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Kozlov A.P. Mammalian tumor-like organs. 1. The role of tumor-like normal organs and atypical tumor organs in the evolution of development (carcino-evo-devo) // Infect. Agents Cancer. 2022b. V. 17. 2. https://doi.org/10.1186/s13027-021-00412-0</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Kozlov A.P. Diagrams describing the evolution of gene expression, the emergence of novel cell types during evolution, and evo-devo // Gene Expr. 2023. V. 22 (3). P. 262–269. https://doi.org/10.14218/GE.2023.00031</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Kozlov A.P. Structural complexity growth as a fundamental law of nature. Multilevel increase in complexity, frozen accidents, and transitory forms in macroevolution // Paleontol. J. 2024. V. 58 (12). P. 1438–1448. https://doi.org/10.1134/S0031030124601312</mixed-citation></ref></ref-list></back></article>
