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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Human Physiology</journal-id><journal-title-group><journal-title xml:lang="en">Human Physiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Физиология человека</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0131-1646</issn><issn publication-format="electronic">3034-6150</issn><publisher><publisher-name xml:lang="en">The Russian Academy of Sciences</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">664005</article-id><article-id pub-id-type="doi">10.31857/S0131164622600720</article-id><article-id pub-id-type="edn">MWAFVW</article-id><article-categories><subj-group subj-group-type="toc-heading"><subject>КРАТКИЕ СООБЩЕНИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Relationship between Dehydroepiandrosterone-Sulfate, Testosterone, Thyroid Hormones, Insulin and Cortisol in Indigenous Men and Women among Representatives of the Indigenous and Newcomer Population of the Yamalo-Nenets Autonomous Okrug</article-title><trans-title-group xml:lang="ru"><trans-title>Корреляционные связи дегидроэпиандростерон-сульфата с тестостероном, тиреоидными гормонами, инсулином и кортизолом у коренных и пришлых жителей Ямало-Ненецкого автономного округа</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Polyakov</surname><given-names>L. M.</given-names></name><name xml:lang="ru"><surname>Поляков</surname><given-names>Л. М.</given-names></name></name-alternatives><email>plm@niibch.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Rozumenko</surname><given-names>A. A.</given-names></name><name xml:lang="ru"><surname>Розуменко</surname><given-names>А. А.</given-names></name></name-alternatives><email>plm@niibch.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Russkikh</surname><given-names>G. S.</given-names></name><name xml:lang="ru"><surname>Русских</surname><given-names>Г. С.</given-names></name></name-alternatives><email>plm@niibch.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Poteryaeva</surname><given-names>O. N.</given-names></name><name xml:lang="ru"><surname>Потеряева</surname><given-names>О. Н.</given-names></name></name-alternatives><email>plm@niibch.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Institute of Biochemistry of Federal Research Center for Fundamental and Translational Medicine</institution></aff><aff><institution xml:lang="ru">Научно-исследовательский институт биохимии
Федерального исследовательского центра фундаментальной и трансляционной медицины</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2023-03-01" publication-format="electronic"><day>01</day><month>03</month><year>2023</year></pub-date><volume>49</volume><issue>2</issue><fpage>81</fpage><lpage>85</lpage><history><date date-type="received" iso-8601-date="2025-02-25"><day>25</day><month>02</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2023, Л.М. Поляков, А.А. Розуменко, Г.С. Русских, О.Н. Потеряева</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2023, Л.М. Поляков, А.А. Розуменко, Г.С. Русских, О.Н. Потеряева</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="en">Л.М. Поляков, А.А. Розуменко, Г.С. Русских, О.Н. Потеряева</copyright-holder><copyright-holder xml:lang="ru">Л.М. Поляков, А.А. Розуменко, Г.С. Русских, О.Н. Потеряева</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/0131-1646/article/view/664005">https://journals.eco-vector.com/0131-1646/article/view/664005</self-uri><abstract xml:lang="en"><p id="idm45181325651216">Using Spearman’s rank correlation we studied the correlations between the serum dehydroepiandrosterone-sulfate (DHEA-S) concenttration and the concentration of testosterone, thyroid-stimulating hormone, thyroxine, triiodothyronine, insulin and cortisol in the indigenous and alien populationof the Yamal-Nenets Autonomous Okrug. A positive correlation was found between the DHEA-S concenttration and testosterone in indigenous women and newcomers. A stronger correlation was found in the group of newcomer women. In indigenous men, DHEA-S was positively correlated with cortisol. The newcomer men showed a positive correlation between DHEA-S and thyroid-stimulating hormone. No correlations were found between the concenttration of DHEA-S with insulin, thyroxine and triiodothyronine in any of the examined groups.</p></abstract><trans-abstract xml:lang="ru"><p id="idm45181325649984">С использованием ранговой корреляции Спирмена представлены корреляционные связи между концентрацией в сыворотке крови дегидроэпиандростерон-сульфата (ДГЭА-С) и концентрацией тестостерона, тиреотропного гормона, тироксина, трийодтиронина, инсулина и кортизола у представителей коренного и пришлого населения Ямало-Ненецкого автономного округа. Показана положительная корреляционная связь между концентрацией в сыворотке крови ДГЭА-С с тестостероном у коренных и пришлых женщин. Более сильная корреляционная связь отмечена в группе пришлых женщин. У коренных мужчин ДГЭА-С положительно коррелировал с кортизолом, а у пришлых мужчин ДГЭА-С положительно коррелировал с тиреотропным гормоном. В обследованных группах не обнаружена корреляционная связь между концентрацией ДГЭА-С с инсулином, тироксином и трийодтиронином.</p></trans-abstract><kwd-group xml:lang="en"><kwd>dehydroepiandrosterone sulfate</kwd><kwd>testosterone</kwd><kwd>thyroid hormones</kwd><kwd>insulin and cortisol</kwd><kwd>village residents of the Yamalo-Nenets Autonomous Okrug.</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>дегидроэпиандростерон-сульфат</kwd><kwd>тестостерон</kwd><kwd>тиреоидные гормоны</kwd><kwd>инсулин</kwd><kwd>кортизол</kwd><kwd>коренные и пришлые жители Ямало-Ненецкого автономного округа.</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Yanase T. Physiological significance of replacement therapy of dehydroepiandrosterone // Intern. Med. 2004. V. 43. № 2. P. 156.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Batrinos M.L. The aging of the endocrine hypothalamus and its dependent endocrine glands // Hormones (Athens). 2012. V. 11. № 3. P. 241.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Ukkola O., Gagnon J., Rankinen T. et al. Age, body mass index, race and other determinants of steroid hormone variability: the HERITAGE Family Study // Eur. J. Endocrinol. 2001. V. 145. № 1. P. 1.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Dutheil F., de Saint Vincent S., Pereira B. et al. DHEA as a Biomarker of Stress: A Systematic Review and Meta-Analysis // Front. Psychiatry. 2021. V. 12. P. 688367.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Lennartsson A.K., Theorell T., Rockwood A.L. et al. Perceived stress at work is associated with lower levels of DHEA-S // PLoS One. 2013. V. 8. № 8. P. e72460.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Поляков Л.М., Розуменко А.А., Русских Г.С. и др. Эндокринный статус у женщин – представительниц коренного и пришлого населения Ямало-Ненецкого автономного округа // Сибирский научный медицинский журн. 2016. Т. 36. № 3. С. 109. Polyakov L.M., Rozumenko A.A., Russkikh G.S. et al. Endocrine status of women-representatives of indigenous people and migrants of Yamal-Nenets Autonomous Area // Sib. Sci. Med. J. 2016. V. 36. № 3. P. 109.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Потеряева О.Н., Осипова Л.П., Русских Г.С. и др. Анализ содержания инсулина, кортизола и глюкозы в сыворотке крови поселковых жителей Ямало-Ненецкого автономного округа // Физиология человека. 2017. Т. 43. № 6. С. 103. Poteryaeva O.N., Osipova L.P., Russkikh G.S. et al. Analysis of Serum Insulin, Cortisol, and Glucose Levels in the Settlement Inhabitants of the Yamalo-Nenets Autonomous Okrug // Human Physiology. 2017. V. 43. № 6. P. 700.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Phillips G.B. Relationship between serum dehydroepiandrosterone sulfate, androstendione, and sex hormones in men and women // Eur. J. Endocrinol. 1996. V. 134. № 2. P. 201.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Burger H.G. Androgen production in women // Fertil. Steril. 2002. V. 77. Suppl. 4. P. 3.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Georgiadis E.I., Matzoros C., Aliferis C., Batrinos M. Are adrenal and testicular androgen levels correlated? // Horm. Metab. Res. 1992. V. 24. № 10. P. 488.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Ahn R.S., Lee Y.J., Choi J.Y. et al. Salivary cortisol and DHEA levels in the Korean population: age-related differences, diurnal rhythm, and correlations with serum levels // Yonsei Med. J. 2007. V. 48. № 3. P. 379.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Muniyappa R., Wong K.A., Baldwin H.L. et al. Dehydroepiandrosterone Secretion in Healthy Older Men and Women: Effects of Testosterone and Growth Hormone Administration in Older Men // J. Clin. Endocrinol. Metab. 2006. V. 91. № 11. P. 4445.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Bendlová B., Vrbíková J., Hill M. et al. Dehydroepiandrosterone in relation to adiposity, glucose tolerance and lipid spectra in Czech non-diabetic population // Physiol. Res. 2008. V. 57. Suppl 1. P. S67.</mixed-citation></ref></ref-list></back></article>
