Human PhysiologyHuman PhysiologyФизиология человека0131-16463034-6150The Russian Academy of Sciences66403410.31857/S0131164624030101BUAIZDОБЗОРЫReview ArticleThe influence of physical activity on the level of chronic inflammation in health and in non-infectious diseasesВлияние физической нагрузки на уровень хронического воспаления в норме и при неинфекционных заболеванияхPahomovN. V.ПахомовН. В.
Russian Federation
dkostchsu@yandex.ruKostuninaD. S.КостюнинаД. С.
Russian Federation
dkostchsu@yandex.ruArtemenkovA. А.АртеменковА. А.
Russian Federation
dkostchsu@yandex.ruCherepovets State UniversityФГБОУ ВО Череповецкий государственный университет1609202450312613725022025Copyright ©; 2024, Russian Academy of SciencesCopyright ©; 2024, Российская академия наук2024Russian Academy of SciencesРоссийская академия наукhttps://journals.eco-vector.com/0131-1646/article/view/664034

In this review we discuss the effects of exercise on systemic inflammation. The influence of moderate continuous training on humoral immunity and cellular immunity is separately considered. Recent data on the molecular mechanisms of this influence, such as myokines secreted by skeletal muscles and adipokines secreted by adipocytes, are discussed. Clinical data are provided on the effect of moderate physical activity on common diseases — cardiovascular diseases, diabetes, cancer, Alzheimer’s disease and others.

В данном обзоре рассматривается влияние физической нагрузки на уровень системного воспаления. Отдельно рассмотрено влияние умеренных постоянных тренировок на участников гуморального иммунитета и клеточного иммунитета. Обсуждаются последние данные о молекулярных механизмах этого влияния, такие как выделяемые скелетными мышцами миокины и выделяемые адипоцитами адипокины. Приводятся клинические данные о влиянии умеренных физических нагрузок на распространенные заболевания — сердечно-сосудистые, диабет, рак, болезни Альцгеймера и другие.

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