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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Human Physiology</journal-id><journal-title-group><journal-title xml:lang="en">Human Physiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Физиология человека</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0131-1646</issn><issn publication-format="electronic">3034-6150</issn><publisher><publisher-name xml:lang="en">The Russian Academy of Sciences</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">664101</article-id><article-id pub-id-type="doi">10.31857/S0131164624060095</article-id><article-id pub-id-type="edn">AFNAHV</article-id><article-categories><subj-group subj-group-type="toc-heading"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">The Commonality of Overtraining Syndrome and Relative Energy Deficit Syndrome in Sports (REDs). Literature Review</article-title><trans-title-group xml:lang="ru"><trans-title>Общность синдрома перетренированности и синдрома относительного дефицита энергии в спорте (REDs). Анализ литературы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gavrilova</surname><given-names>E. A.</given-names></name><name xml:lang="ru"><surname>Гаврилова</surname><given-names>Е. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>gavrilovaea@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Churganov</surname><given-names>O. A.</given-names></name><name xml:lang="ru"><surname>Чурганов</surname><given-names>О. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>gavrilovaea@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Pavlova</surname><given-names>O. Y.</given-names></name><name xml:lang="ru"><surname>Павлова</surname><given-names>О. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>gavrilovaea@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bryntseva</surname><given-names>E. V.</given-names></name><name xml:lang="ru"><surname>Брынцева</surname><given-names>Е. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>gavrilovaea@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Rasskazova</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Рассказова</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>gavrilovaea@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gorkin</surname><given-names>M. V.</given-names></name><name xml:lang="ru"><surname>Горкин</surname><given-names>М. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>gavrilovaea@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sarkisov</surname><given-names>A. K.</given-names></name><name xml:lang="ru"><surname>Саркисов</surname><given-names>А. К.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>gavrilovaea@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Didora</surname><given-names>A. B.</given-names></name><name xml:lang="ru"><surname>Дидора</surname><given-names>А. Б.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>gavrilovaea@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shitova</surname><given-names>V. I.</given-names></name><name xml:lang="ru"><surname>Шитова</surname><given-names>В. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>gavrilovaea@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">North-Western State Medical University named after I.I. Mechnikov</institution></aff><aff><institution xml:lang="ru">Северо-Западный государственный медицинский университет имени И.И. Мечникова</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2024-12-12" publication-format="electronic"><day>12</day><month>12</month><year>2024</year></pub-date><volume>50</volume><issue>6</issue><fpage>80</fpage><lpage>91</lpage><history><date date-type="received" iso-8601-date="2025-02-25"><day>25</day><month>02</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Russian Academy of Sciences</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, Российская академия наук</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Russian Academy of Sciences</copyright-holder><copyright-holder xml:lang="ru">Российская академия наук</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/0131-1646/article/view/664101">https://journals.eco-vector.com/0131-1646/article/view/664101</self-uri><abstract xml:lang="en"><p>The purpose of article is analysis of the literature comparing the clinical manifestations of overtraining syndrome (OTS) and relative energy deficiency syndrome in sports (REDs). The analysis of publications connected to OTS and REDs was carried out from two literature databases (PubMed and Elibrary.ru). The selection of works for analysis was carried out from 514 articles of two literature databases on the problem of the commonality of OTS and REDs, the connection between these syndromes, as well as issues of impaired availability of energy and nutrients in OTS. A comparative analysis of the clinical manifestations of the two syndromes and evidence of the hypothesis that the relative lack of energy in sports is one of the reasons (theories) for the development of overtraining syndrome in an athlete was carried out. A review and analysis of the literature showed that REDs can be considered a manifestation of OTS, and relative energy deficit in sports (REDs) is only one of the reasons (theories) for the development of overtraining syndrome in athletes, along with other theories (theory of cytokines, oxidative stress, fatigue of the central nervous system and etc.).</p></abstract><trans-abstract xml:lang="ru"><p>Цель данного обзора – анализ литературы по сравнению клинических проявлений синдрома перетренированности (СП) и синдрома относительного дефицита энергии в спорте (<italic>REDs</italic>). Поиск и анализ публикаций из двух литературных баз (<italic>PubMed </italic>и <italic>Elibrary.ru</italic>) по СП и <italic>REDs</italic>. Отбор работ для анализа осуществлялся из 514 статей двух литературных баз по проблеме общности СП и <italic>REDs</italic>, связи данных синдромов, а также вопросам нарушения доступности энергии и пищевых веществ при СП. Проведен сравнительный анализ клинических проявлений двух синдромов и доказательства гипотезы о том, что относительный дефицит энергии в спорте – это одна из причин (теорий) развития у спортсмена синдрома перетренированности. Анализ литературы показал, что <italic>REDs </italic>можно считать проявлением СП, а относительный дефицит энергии в спорте (<italic>REDs</italic>) – это лишь одна из причин (теорий) развития у спортсменов синдрома перетренированности, наряду с другими теориями (цитокиновая, окислительного стресса, утомления центральной нервной системы и др.).</p></trans-abstract><kwd-group xml:lang="en"><kwd>athletes</kwd><kwd>overtraining syndrome</kwd><kwd>relative energy deficiency syndrome in sports (REDs)</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>спортсмены</kwd><kwd>синдром перетренированности</kwd><kwd>синдром относительного дефицита энергии в спорте (REDs)</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>McKenzie R.T. The place of manipulation and corrective gymnastics in treatment // Cal. State J. Med. 1923. V. 21. № 11. 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