Human PhysiologyHuman PhysiologyФизиология человека0131-16463034-6150The Russian Academy of Sciences68403010.31857/S0131164625030102TPZTSLОБЗОРЫReview ArticleParticipation of the gut microbiome in the regulation of skeletal muscle metabolismУчастие микробиома кишечника в регуляции метаболизма скелетных мышцAstratenkovaI. V.АстратенковаИ. В.
Russian Federation
astratenkova@mail.ruRogozkinV. A.РогозкинВ. А.
Russian Federation
astratenkova@mail.ruSaint Petersburg State UniversityСанкт-Петербургский государственный университетSaint Petersburg Research Institute of Physical CultureСанкт-Петербургский НИИ физической культуры04072025513981091206202512062025Copyright ©; 2025, Russian Academy of SciencesCopyright ©; 2025, Российская академия наук2025Russian Academy of SciencesРоссийская академия наукhttps://journals.eco-vector.com/0131-1646/article/view/684030

The gut microbiota contributes to the regulation of skeletal muscle metabolism in various human functional states through a variety of formed metabolites that can be used as energy substrates or are signaling and regulatory molecules. The review presents the results of studies on the effects of bacterial short-chain fatty acids on signaling pathways regulating skeletal muscle metabolism and providing increased physical performance and improved human health.

Микробиота кишечника вносит свой вклад в регуляцию метаболизма скелетных мышц при различных функциональных состояниях человека за счет множества образованных метаболитов, которые могут быть использованы в качестве энергетических субстратов или являются сигнальными и регуляторными молекулами. В данном обзоре представлены результаты исследований влияния бактериальных короткоцепочечных жирных кислот на сигнальные пути, регулирующие метаболизм скелетных мышц и обеспечивающие повышение физической работоспособности и улучшение здоровья человека.

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