Sensory SystemsSensory SystemsСенсорные системы0235-00923034-5936The Russian Academy of Sciences69675010.7868/S3034593625030021ОБЗОРЫResearch ArticleDisease detection by volatile organic compound analysis: I. Detection dogsОбнаружение заболеваний по анализу летучих органических соединений: I. Собаки-детекторыRodionovaE. I.РодионоваЕ. И.a.rodionova@gmail.comKiryukhinaO. O.КирюхинаО. О.PentoA. V.ПентоА. В.NikiforovS. M.НикифоровС. М.Kharkevich Institute for information transmission problems, Russian Academy of SciencesФедеральное государственное бюджетное учреждение науки Институт проблем передачи информации им. А.А. Харкевича РАНProkhorov General Physics Institute of the Russian Academy of SciencesИнститут общей физики им. А.М. Прохорова РАН15122025393VOL 39, NO3 (2025)ТОМ 39, №3 (2025)132421112025Copyright ©; 2025, Russian Academy of SciencesCopyright ©; 2025, Российская академия наук2025Russian Academy of SciencesРоссийская академия наукhttps://journals.eco-vector.com/0235-0092/article/view/696750

The paper presents a review of modern research on the role of volatile organic compounds in the diagnosis of oncological diseases. The possibilities of canine olfaction, the use of detection dogs to identify diseased organisms among healthy organisms, the difficulties of this method, its comparison with instrumental methods of research are considered. The review includes the results of the authors’ own research and literature data on the specific features of the use of trained animals in the study of volatile organic compounds associated with the development of cancer. Possible ways of this research field development are suggested.

В работе представлен обзор современных исследований роли летучих органических соединений в диагностике онкологических заболеваний. Рассмотрены возможности обоняния собак, использование животных-биосенсоров в выделении больных организмов среди здоровых, сложности этого метода, сравнение его с инструментальными методами исследований. В обзор включены результаты собственных исследований авторов и литературные данные об особенностях применения обученных животных в изучении летучих органических соединений, связанных с развитием онкологических заболеваний. Предложены возможные пути развития этой области исследований.

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