Modern view on the problem of keloid scars

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详细

Serious skin injuries can lead to the formation of scars, in particular hypertrophic and keloid scars. The prevalence of keloids and hypertrophic scars varies among different populations.

Scar formation is a natural process during wound healing, but when keloid scars form, regeneration is impaired. It is generally accepted that a keloid scar is formed as a result of increased synthesis of collagen and extracellular matrix against the background of reduced degradation of these products. Clinically, keloid and hypertrophic scars have a number of differences. Thus, the formation of a keloid scar takes a longer period; it extends beyond the boundaries of the original wound and is often accompanied by itching, pain, and impairs motor function. Treatment of keloid scars is a very difficult task, and inadequate treatment can aggravate the patient's condition.

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作者简介

E. Dvoriankova

Center for Theoretical Problems of Physicochemical Pharmacology, Russian; Academy of Sciences Bashkir State Medical University

Email: marykor@bk.ru
ORCID iD: 0000-0002-2458-419X

Doctor of Medical Sciences

俄罗斯联邦, Moscow; Ufa

I. Korsunskaya

Center for Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences

编辑信件的主要联系方式.
Email: marykor@bk.ru
ORCID iD: 0000-0002-6583-0318

Doctor of Medical Sciences, Professor

俄罗斯联邦, Moscow

M. Karapetyan

Moscow Research and Practical Center of Dermatovenereology and Cosmetology

Email: marykor@bk.ru
ORCID iD: 0000-0002-4862-2779
俄罗斯联邦, Moscow

G. Shevchenko

Peoples’ Friendship University of Russia

Email: marykor@bk.ru
ORCID iD: 0000-0002-2572-2312
俄罗斯联邦, Moscow

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