Clinical and prognostic value of NT-proBNP and sST2 biomarkers in elderly patients with heart failure and comorbidities

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Chronic heart failure (HF) in elderly patients is characterized by high morbidity and mortality, especially in the presence of comorbidities. The article presents a review of current data on the prognostic value of blood biomarkers — N-terminal pro-brain natriuretic peptide (NT-proBNP) and soluble ST2 receptor (sST2) in elderly comorbid patients with chronic heart failure (CHF). Based on the analysis, the rationale for the combined use of NT-proBNP and sST2 for accurate risk stratification and personalization of therapeutic approaches in elderly patients with CHF and multiple comorbidities is substantiated.

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作者简介

I. Kochetkova

Burdenko Voronezh State Medical University

Email: iri4217@yandex.ru
SPIN 代码: 9933-5015

Candidate of Medical Sciences

俄罗斯联邦, Voronezh

T. Trofimova

Voronezh State University

Email: iri4217@yandex.ru
ORCID iD: 0009-0006-2818-9134
SPIN 代码: 4567-4489

Candidate of Medical Sciences

俄罗斯联邦, Voronezh

Yu. Lykov

Belgorod State National Research University

Email: iri4217@yandex.ru
ORCID iD: 0000-0002-4185-5502
SPIN 代码: 2822-9134
俄罗斯联邦, Belgorod

A. Kukharchuk

Belgorod State National Research University

编辑信件的主要联系方式.
Email: iri4217@yandex.ru
ORCID iD: 0000-0003-3881-2138
SPIN 代码: 5035-1117
俄罗斯联邦, Belgorod

参考

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  3. Morrow D.A. Cardiac Biomarkers and Heart Failure [Internet]. Washington (DC): American College of Cardiology, 2015. URL: https://www.acc.org/Latest-in-Cardiology/Articles/2015/02/09/13/00/Cardiac-Biomarkers-and-Heart-Failure
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