<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Obstetrics and Gynecology</journal-id><journal-title-group><journal-title xml:lang="en">Obstetrics and Gynecology</journal-title><trans-title-group xml:lang="ru"><trans-title>Акушерство и гинекология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0300-9092</issn><issn publication-format="electronic">2412-5679</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">246157</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Local action of glycyrrhizic acid in genital viral infections</article-title><trans-title-group xml:lang="ru"><trans-title>Локальное действие глицирризиновой кислоты при вирусных инфекциях половых органов</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shurshalina</surname><given-names>Anna Vladimirovna</given-names></name><name xml:lang="ru"><surname>Шуршалина</surname><given-names>Анна Владимировна</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, старший научный сотрудник лаборатории клинической иммунологии; ФГУ Научный центр акушерства, гинекологии и перинатологии им. В. И. Кулакова Росмедтехнологий, Москва</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Krechetova</surname><given-names>L V</given-names></name><name xml:lang="ru"><surname>Кречетова</surname><given-names>Л В</given-names></name></name-alternatives><bio xml:lang="ru"><p>ФГУ Научный центр акушерства, гинекологии и перинатологии им. В. И. Кулакова Росмедтехнологий, Москва</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ziganshina</surname><given-names>M M</given-names></name><name xml:lang="ru"><surname>Зиганшина</surname><given-names>М М</given-names></name></name-alternatives><bio xml:lang="ru"><p>ФГУ Научный центр акушерства, гинекологии и перинатологии им. В. И. Кулакова Росмедтехнологий, Москва</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sukhikh</surname><given-names>G T</given-names></name><name xml:lang="ru"><surname>Сухих</surname><given-names>Г Т</given-names></name></name-alternatives><bio xml:lang="ru"><p>ФГУ Научный центр акушерства, гинекологии и перинатологии им. В. И. Кулакова Росмедтехнологий, Москва</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Shurshalina</surname><given-names>A V</given-names></name><bio xml:lang="en"><p>V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Krechetova</surname><given-names>L V</given-names></name><bio xml:lang="en"><p>V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Ziganshina</surname><given-names>M M</given-names></name><bio xml:lang="en"><p>V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Sukhikh</surname><given-names>G T</given-names></name><bio xml:lang="en"><p>V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow</p></bio><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ФГУ Научный центр акушерства, гинекологии и перинатологии им. В. И. Кулакова Росмедтехнологий, Москва</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow</institution></aff><aff><institution xml:lang="ru"></institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2009-06-15" publication-format="electronic"><day>15</day><month>06</month><year>2009</year></pub-date><issue>3</issue><issue-title xml:lang="en">NO3 (2009)</issue-title><issue-title xml:lang="ru">№3 (2009)</issue-title><fpage>63</fpage><lpage>65</lpage><history><date date-type="received" iso-8601-date="2023-02-17"><day>17</day><month>02</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2009, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2009, ООО «Бионика Медиа»</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/0300-9092/article/view/246157">https://journals.eco-vector.com/0300-9092/article/view/246157</self-uri><abstract xml:lang="en"><p>Glycyrrhizic acid was applied to 90 patients with genital viral infection. With the treatment, there was a reduction in the level of proinflammatory cytokines and an increase in the content of anti-inflammatory cytokines, suggesting the marked anti-inflammatory and immunomodulatory effects of the agent.</p></abstract><trans-abstract xml:lang="ru"><p>Глицирризиновая кислота применена у 90 больных с вирусной инфекцией половых органов. Под влиянием лечения отмечено снижение уровня провоспалительных и повышение содержания противовоспалительных цитокинов, что свидетельствует о выраженном противовоспалительном и иммуномодулирующем эффекте препарата.</p></trans-abstract><kwd-group xml:lang="en"><kwd>cytomegalovirus</kwd><kwd>genital infection</kwd><kwd>genital herpes</kwd><kwd>genital papillomavirus infection</kwd><kwd>pro- and anti-inflammatory cytokines</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>цитомегаловирус</kwd><kwd>инфекция половых органов</kwd><kwd>генитальный герпес</kwd><kwd>папилломавирусная инфекция половых органов</kwd><kwd>цитокины про- и противовоспалительные</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Кашкин К. П. // Клин. лаб. диагн. - 1998. - № 11. - С. 21-32.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Марченко Л. А. Генитальная герпетическая инфекция у женщин (клиника, диагностика, лечение): Автореф. дис. ... д-ра мед. наук. - М., 1997.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Пальцев М. А., Иванов А. А. Межклеточные взаимодействия. - М., 1995.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Пальцев М. А. // Арх. пат. - 1996. - № 6. - С. 3-7.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Сидельникова В. М. Привычная потеря беременности. - М., 2005.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Шубич М. Г. // Арх. пат. - 1997. - № 2. - С. 3-8.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Carr D. J., Tomanek L. // Curr. Top. Microbiol. Immunol. - 2006. - Vol. 30, N 3. - P. 47-65.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Center for Disease Control and Prevention. Sexually transmitted disease treatment guidelines 2006. Morbid. Mortal. Wkly Rep. - 2006. - Vol. 55. - No.RR-11.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Gill S. E., Parks W. C. // Int. J. Biochem. Cell Biol. - 2008. - Vol. 40, N 6-7. - P. 1334-1347.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Gordon J. D., Speroff L. Handbook for Clinical Gynecologic Endocrinology and Infertility. - Philadelphia, 2002. - P. 515.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Kim K. W., Romero R., Park H. S. // Am. J. Obstetr. Gynecol. - 2007. - Vol. 197, N 3. - P. 292.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Lee S., Zheng M., Kim B. // J. Clin. Invest. - 2002. - Vol. 110, N 8. - P. 1105-1111.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Manicone A. M., McGuire J. K. // Semin. Cell Biol. - 2008. - Vol. 19, N 1. - P. 34-41.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Reynolds J. J. // Oral Dis. - 1996. - Vol. 2, N 1. - P. 70-76.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Saalbach A., Arnhold J., Lessig J. // Eur. J. Immunol. - 2008. - Vol. 38, N 5. - P. 1391-1403.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Stamenkovic I. // J. Pathol. - 2003. - N 4. - P. 448-464.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Van Lint P., Libert C. // J. Leukoc. Biol. - 2007. - Vol. 82, N 6. - P. 135-138.</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Wuest T. R., Carr D. J. // Front. Biosci. - 2008. - Vol. 13, N 1. - P. 4862-4872.</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Yang Y. N., Bauer D., Li H. P. // Zhonghua Yan Ke Za Zhi. - 2004. - Vol. 40, N 6. - P. 395-399.</mixed-citation></ref></ref-list></back></article>
