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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Obstetrics and Gynecology</journal-id><journal-title-group><journal-title xml:lang="en">Obstetrics and Gynecology</journal-title><trans-title-group xml:lang="ru"><trans-title>Акушерство и гинекология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0300-9092</issn><issn publication-format="electronic">2412-5679</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">246515</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">PREVENTION OF AFTERBIRTH AND EARLY POSTPARTUM HEMORRHAGE: ACTIVE OR WAIT-AND-SEE POLICY?</article-title><trans-title-group xml:lang="ru"><trans-title>ПРОФИЛАКТИКА КРОВОТЕЧЕНИЙ В ПОСЛЕДОВОМ И РАННЕМ ПОСЛЕРОДОВОМ ПЕРИОДЕ. АКТИВНАЯ ИЛИ ВЫЖИДАТЕЛЬНАЯ ТАКТИКА?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>BAYEV</surname><given-names>O. R</given-names></name><name xml:lang="ru"><surname>БАЕВ</surname><given-names>Олег Радомирович</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, проф., руководитель родильного отд-ния</p></bio><email>o_baev@oparina4.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia</institution></aff><aff><institution xml:lang="ru">ФГУ Научный центр акушерства, гинекологии и перинатологии им. академика В.И. Кулакова Минздравсоцразвития России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2011-06-15" publication-format="electronic"><day>15</day><month>06</month><year>2011</year></pub-date><issue>6</issue><issue-title xml:lang="en">NO6 (2011)</issue-title><issue-title xml:lang="ru">№6 (2011)</issue-title><fpage>27</fpage><lpage>30</lpage><history><date date-type="received" iso-8601-date="2023-02-17"><day>17</day><month>02</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2011, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2011, ООО «Бионика Медиа»</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/0300-9092/article/view/246515">https://journals.eco-vector.com/0300-9092/article/view/246515</self-uri><abstract xml:lang="en"><p>Ministry of Health and Social Development of Russia, Moscow The author has examined the data currently available in the literature on labor management tactics for the prevention of afterbirth and early postpartum hemorrhage. Wait-to-see policy envisages the natural process of labor and early postpartum. Active policy is distinguished by the use of uterotonic agents and umbilical ligation and crossing within 1 minute after childbirth and by the implementation of measures for rapid birth of the placenta with further uterine massage. The results of systematic reviews of randomized clinical trials have strongly demonstrated that the active management tactic, primarily the use of uterotonic drugs, assists in reducing blood loss, the rate of postpartum hemorrhages, and the duration of the third stage of labor. In the literature there is now no agreement regarding the benefits of administration of an uterotonic agent before or after birth of the placenta and the optimal time for umbilical ligation to prevent hemorrhage. The active management tactic may be accompanied by a number of side effects and complications. However, the frequency of complications is low and the degree of side effects is generally of no significant clinical value. The active management tactic is an effective method for reducing afterbirth and early postpartum blood loss.</p></abstract><trans-abstract xml:lang="ru"><p>Изучены современные данные литературы, посвященной тактике ведения родов для профилактики кровотечений в последовом и раннем послеродовом периодах. При выжидательной тактике предусмотрено естественное течение родов и раннего послеродового периода. Активная тактика отличается применением утеротонических препаратов, пережатием и пересечением пуповины в течение 1 мин после рождения ребенка, применением мероприятий для быстрого рождения последа с последующим массажем матки. Результаты систематических обзоров рандомизированных клинических исследований убедительно показали, что активная тактика ведения, в первую очередь применение утеротоников, способствует снижению величины кровопотери, частоты послеродовых кровотечений и продолжительности 3-го периода родов. В настоящее время в литературе нет единого мнения о преимуществах введения утеротоника до или после рождения последа, а также оптимального времени для пережатия пуповины с позиций профилактики кровотечений. Активная тактика ведения может сопровождаться рядом побочных эффектов и осложнений. Однако частота осложнений низкая, а степень выраженности побочных эффектов обычно не имеет выраженного клинического значения. Активная тактика ведения является эффективным методом снижения кровопотери в последовом и раннем послеродовом периодах.</p></trans-abstract><kwd-group xml:lang="en"><kwd>the third stage of labor</kwd><kwd>early postpartum</kwd><kwd>postpartum hemorrhage</kwd><kwd>prevention</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>3-й период родов</kwd><kwd>ранний послеродовой период</kwd><kwd>послеродовое кровотечение</kwd><kwd>профилактика</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Радзинский В.Е., Жуковский Я.Г., Оленева М.А. и др. Кровотечения в акушерстве. Перспективы современных технологий // Материалы VIII Всероссийского научного форума «Мать и дитя». 3—6 октября. М., 2006. — С. 214—215.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Серов В.Н. Профилактика материнской смертности // Рус. мед. журн. — 2008. — Т. 16, № 1. — С. 3—5.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Althabe F., Aleman A., Tomasso G. et al. A pilot randomized controlled trial of controlled cord traction to reduce postpartum blood loss // Int. J. Gynecol. Obstet. — 2009. — Vol. 107. — P. 4—7.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Baskett T.F. Equipment tray for postpartum hemorrhage // A Textbook of postpartum hemorrhage. Comprehensive guide to evaluation, management and surgical intervention / Eds Ch. B. Lynch et al. — Sapiens Publishing, 2006. — P. 179—181.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Begley C.M., Gyte G.M.L., Murphy D.J. et al. Active versus expectant management for women in the third stage of labour // Cochrane Database Syst. Rev. — 2010. — Issue 7. — Art. N: CD007412.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Bj0rnerem A., Acharya G., 0ian P., Maltau J.M. Postpartum hemorrhage — prophylaxis and treatment in Norway // T. Norske Laegeforen. — 2002. — Vol. 122, № 26. — P. 2536— 2537.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Callaghan W.M., Kuklina E.V., Berg C.J. Trends in postpartum hemorrhage: United States, 1994—2006 // Am. J. Obstet. Gynecol. — 2010. — Vol. 202, № 4. — P. 353.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Cameron C.A., Roberts C.L., Olive E.C. et al. Trends in postpartum haemorrhage // Aust. N. Z. J. Publ. Hlth. — 2006. — Vol. 30, № 2. — P. 151—156.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Chong Yap-Seng, Su Lin-Lin, Arulkumara Sabaratnam. Current strategies for the prevention of postpartum haemorrhage in the third stage of labour. Curr. Opin.Obstet. Gynecol. — 2004. — Vol. 16. — P. 143—150.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Cotter A.M., Ness A., Tolosa J.E. Prophylactic oxytocin for the third stage of labour // Cochrane Database Syst. Rev. — 2001. — Issue 4. DOI: 10.1002/14651858.CD001808.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Farrar D., Tuffnell D., Airey R., Duley L. Care during the third stage of labour: A postal survey of UK midwives and obstetricians // BMC Pregnancy and Childbirth. — 2010. — Vol. 10. — P. 23.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Festin M.R., Lumbiganon Pisake, Tolosa J.E. et al. International survey on variations in practice of the management of the third stage of labour // Bull. Wld Hlth Org. — 2003. — Vol. 81, № 4. — P. 286—291.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Fujimoto M., Takeuchi K., Sugimoto M., Maruo T. Prevention of postpartum hemorrhage by uterotonic agents: comparison of oxytocin and methylergometrine in the management of the third stage of labor // Acta Obstet. Gynecol. Scand. — 2006. — Vol. 85, — № 11. — P. 1310—1314.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Huh W.K., Chelmow D., Malone F.D. A double-blinded, randomized controlled trial of oxytocin at the beginning versus the end of the third stage of labor for prevention of postpartum hemorrhage // Gynecol. Obstet. Invest. — 2004. — Vol. 58, № 2. — P. 72—76.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Jackson K.W., Allbert J.R., Schemmer G.K. et al. A randomized controlled trial comparing oxytocin administration before and after placental delivery in the prevention of postpartum hemorrhage // Am. J. Obstet. Gynecol. — 2001. — Vol. 185. — P. 873—877.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Leduc D., Senikas V., Lalonde A.B. et al. Active management of the third stage of labour: prevention and treatment of postpartum hemorrhage // J. Obstet. Gynaecol. Can. — 2009. — Vol. 31, № 10. — P. 980—993.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Oyelese Y., Scorza W.E., Mastrolia R., Smulian J. C. Postpartum hemorrhage // Obstet. Gynecol. Clin. N. Am. — 2007. — Vol. 34, № 3. — P. 421—441.</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Postpartum haemorrage (PPH) — Framework for prevention, early recognition &amp; management. Policy directive. Primary health and community partnerships. — Sydney, 2005.</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Prendiville W., O’Connell M. Active management of the third stage of labor // A Textbook of Postpartum Hemorrhage. Comprehensive guide to evaluation, management and surgical intervention / Eds Ch.B. Lynch et al. — Sapiens Publishing, 2006. — P. 98—113.</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Prendiville W., Elbourne D., McDonald S.J. Active versus expectant management in the third stage of labour // Cochrane Database Syst. Rev. — 2009. — Issue 3. DOI: 10.1002/14651858.CD000007.</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>Soltani H., Hutchon D.R., Poulose T.A. Timing of prophylactic uterotonics for the third stage of labour after vaginal birth // Cochrane Database Syst. Rev. — 2010. — Issue 8. — CD006173.</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>WHO Recommendations for the prevention of postpartum haemorrhage. Mathai M., Gulmezoglu M., Hill S. WHO Document production service. — Geneva, 2007. http:// whqlibdoc.who.int/hq/2007/WHO_MPS_07.06_eng.pdf</mixed-citation></ref></ref-list></back></article>
