Obstetrics and GynecologyObstetrics and GynecologyАкушерство и гинекология0300-90922412-5679Bionika Media24803910.18565/aig.2017.12.5-15ArticlesСтатьиReview ArticleUrogenital mycoplasmosis and pregnancyУрогенитальный микоплазмоз и беременностьPoderAiriПыдерАйри

Dermatologist-Venerologist

доктор медицины, дерматолог-венеролог, Тартуская университетская больница, дерматологическая клиника.

Airi.Poder@std.eeHaldreMadliХалдреМадли

MD, Physician

доктор медицины, врач, Фонд клиник Университета Тарту

Madli.Haldre@gmail.eeTartu Univerisity Clinics FoundationКлиника Тартуского университетаТартуская университетская больницаTartu Univerisity Clinics FoundationКлиника Тартуского университета1512201712NO12 (2017)№12 (2017)51518022023Copyright ©; 2017, Bionika MediaCopyright ©; 2017, ООО «Бионика Медиа»2017Bionika MediaООО «Бионика Медиа»https://journals.eco-vector.com/0300-9092/article/view/248039

Urogenital mycoplasmas - Ureaplasma urealyticum, Ureaplasma parvum and Mycoplasma hominis have long been considered commensals of human urogenital microflora. Objective. To clarify whether these bacteria could cause or be associated with various obstetric complications. Materials and methods. Data from epidemiological studies published on this topic were included. Results. Epidemiologic studies have found high prevalence of Ureaplasma spp. and M. hominis among otherwise healthy population. On the other hand, U.urealyticum, U. parvum and M. hominis have increasingly been linked to adverse pregnancy outcomes such as spontaneous pre-term labor, pre-term premature rupture of fetal membranes, miscarriage, stillbirth and low birth weight. However, no convincing causal relationship has been shown. Studies have shown that antibiotics resistance is on the rise and differs considerably by regions. Conclusion. Screening of asymptomatic patients for M. hominis, U. urealyticum and U. parvum is currently still not indicated.

Бактерии уреаплазма уреалитикум (Ureaplasma urealyticum), уреаплазма парвум (Ureaplasma parvum) и микоплазма хоминис (Mycoplasma hominis), вызывающие урогенитальный микоплазмоз, в течение длительного времени считались микроорганизмами-комменсалами урогенитальной микрофлоры организма человека. Цель исследования. Рассмотреть вопрос, есть ли связь между этими бактериями и различными акушерскими осложнениями. Материал и методы. Включены данные эпидемиологических исследований, опубликованных по данной теме. Результаты. Эпидемиологические исследования обнаружили высокую распространенность бактерий Ureaplasma spp. и M. hominis у популяции, не имеющей других заболеваний. С другой стороны, наличие бактерий U. urealyticum, U. parvum и M. hominis все чаще связаны с неблагоприятными исходами беременности: спонтанными преждевременными родами, преждевременным разрывом плодных оболочек, выкидышами, мертворождением или низким весом при рождении. Однако не было убедительных доказательств причинно-следственных взаимосвязей. Исследования выявили, что устойчивость к антибиотикам неуклонно возрастает и в значительной степени различается в разных регионах. Заключение. До настоящего времени скрининг на наличие бактерий M. hominis, U. urealyticum и U. parvum в отсутствие симптомов не считается целесообразным.

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