Obstetrics and GynecologyObstetrics and GynecologyАкушерство и гинекология0300-90922412-5679Bionika Media24827910.18565/aig.2018.12.18-22ArticlesСтатьиReview ArticleMenarche as a pubertal stage and its genetic determinantsМенархе как этап пубертатного развития и его генетические детерминантыPonomarenkoIrina V.ПономаренкоИрина Васильевна

MD, associate professor of the Department of Biomedical Disciplines of the Medical Institute

к.м.н, доцент кафедры медико-биологических дисциплин медицинского института

ponomarenko_i@bsu.edu.ruChurnosovMikhail I.ЧурносовМихаил Иванович

MD, professor, head of the Department of Biomedical Disciplines Medical Faculty

д.м.н., профессор, заведующий кафедрой медико-биологических дисциплин медицинского института

churnosov@bsu.edu.ruBelgorod State National Research UniversityФГАОУ ВО «Белгородский государственный национальный исследовательский университет»1512201812NO12 (2018)№12 (2018)182218022023Copyright ©; 2018, Bionika MediaCopyright ©; 2018, ООО «Бионика Медиа»2018Bionika MediaООО «Бионика Медиа»https://journals.eco-vector.com/0300-9092/article/view/248279

The paper carries out a systems analysis of the data available in the current literature on menarche as a pubertal stage and its molecular genetic determinants. It presents studies of menarche formation during pubertal development, as well as molecular genetic factors for its determinants. According to the literature, age at menarche is an important indicator of pubertal development in a woman and has molecular genetic determinants.

Проведен систематический анализ данных, имеющихся в современной литературе, о менархе как этапе пубертатного развития и его молекулярно-генетических детерминантах. Приведены исследования формирования менархе в процессе пубертатного развития и молекулярно-генетических факторов его определяющих. Согласно литературным данным, возраст менархе является важным показателем пубертатного развития женщины и имеет молекулярно-генетические детерминанты.

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