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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Obstetrics and Gynecology</journal-id><journal-title-group><journal-title xml:lang="en">Obstetrics and Gynecology</journal-title><trans-title-group xml:lang="ru"><trans-title>Акушерство и гинекология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0300-9092</issn><issn publication-format="electronic">2412-5679</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">337878</article-id><article-id pub-id-type="doi">10.18565/aig.2022.263</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Experience with surgery for adenomyosis and assessment of reproductive outcomes</article-title><trans-title-group xml:lang="ru"><trans-title>Хирургический опыт операций по поводу аденомиоза и оценка репродуктивных исходов</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7807-4929</contrib-id><name-alternatives><name xml:lang="en"><surname>Bezhenar</surname><given-names>Vitaliy F.</given-names></name><name xml:lang="ru"><surname>Беженарь</surname><given-names>Виталий Федорович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dr. Med. Sci., Professor, Head of the Department of Obstetrics, Gynecology and Neonatology/Obstetrics, Gynecology and Reproductology; Chief Freelance Specialist obstetrician-gynecologist of the Health Committee of the Government of St. Petersburg</p></bio><bio xml:lang="ru"><p>д.м.н., профессор, заведующий кафедрами акушерства, гинекологии и неонатологии/акушерства, гинекологии и репродуктологии; Главный внештатный специалист акушер-гинеколог Комитета по здравоохранению Правительства Санкт-Петербурга</p></bio><email>bez-vitaly@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2149-5957</contrib-id><name-alternatives><name xml:lang="en"><surname>Krylov</surname><given-names>Kirill Yu.</given-names></name><name xml:lang="ru"><surname>Крылов</surname><given-names>Кирилл Юрьевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD, obstetrician-gynecologist, Senior Researcher at the Department of Gynecology</p></bio><bio xml:lang="ru"><p>к.м.н., врач акушер-гинеколог, с.н.с. отдела гинекологии</p></bio><email>drkrylov@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Makarenko</surname><given-names>Tatyana A.</given-names></name><name xml:lang="ru"><surname>Макаренко</surname><given-names>Татьяна Александровна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dr. Med. Sci., Associate Professor, Head of the Department of Operative Gynecology, Institute of Postgraduate Education</p></bio><bio xml:lang="ru"><p>д.м.н., доцент, заведующая кафедрой оперативной гинекологии института последипломного образования</p></bio><email>makarenko7777@yandex.ru</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8906-8356</contrib-id><name-alternatives><name xml:lang="en"><surname>Matukhin</surname><given-names>Valeriy I.</given-names></name><name xml:lang="ru"><surname>Матухин</surname><given-names>Валерий Игоревич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Assistant at the Department of Obstetrics and Gynecology</p></bio><bio xml:lang="ru"><p>ассистент кафедры акушерства и гинекологии</p></bio><email>val-matukhin@mail.ru</email><xref ref-type="aff" rid="aff4"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3548-0468</contrib-id><name-alternatives><name xml:lang="en"><surname>Rukhliada</surname><given-names>Nikolai N.</given-names></name><name xml:lang="ru"><surname>Рухляда</surname><given-names>Николай Николаевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dr. Med. Sci., Professor, Head of the Department of Obstetrics and Gynecology</p></bio><bio xml:lang="ru"><p>д.м.н., профессор, заведующий кафедрой акушерства и гинекологии</p></bio><email>nickolasr@mail.ru</email><xref ref-type="aff" rid="aff4"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tskhay</surname><given-names>Vitaly B.</given-names></name><name xml:lang="ru"><surname>Цхай</surname><given-names>Виталий Борисович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dr. Med. Sci., Professor, Head of the Department of Perinatology, Obstetrics and Gynecology; Scientific Supervisor in Obstetrics and Gynecology</p></bio><bio xml:lang="ru"><p>д.м.н., профессор, заведующий кафедрой перинатологии, акушерства и гинекологии; Научный руководитель по акушерству и гинекологии</p></bio><email>tchai@yandex.ru</email><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Academician I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">I.I. Dzhanelidze Saint Petersburg Research Institute of Emergence Care</institution></aff><aff><institution xml:lang="ru">ГБУ СПб «Научно-исследовательский институт скорой помощи имени И.И. Джанелидзе»</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Красноярский государственный медицинский университет имени В.Ф. Войно-Ясенецкого» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">Saint Petersburg State Pediatric Medical University, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Санкт-Петербургский государственный педиатрический медицинский университет» Министерства здравоохранения Российской Федерации</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2023-04-18" publication-format="electronic"><day>18</day><month>04</month><year>2023</year></pub-date><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>79</fpage><lpage>86</lpage><history><date date-type="received" iso-8601-date="2023-04-16"><day>16</day><month>04</month><year>2023</year></date><date date-type="accepted" iso-8601-date="2023-04-16"><day>16</day><month>04</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2023, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2023, ООО «Бионика Медиа»</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/0300-9092/article/view/337878">https://journals.eco-vector.com/0300-9092/article/view/337878</self-uri><abstract xml:lang="en"><p><italic>Adenomyosis is a variety of the benign pathological process, in which tissue in endometriosis affects the muscular layer of the uterus. The main principle of surgical intervention is the removal of myometrial tissue with invasion of endometriosis. The prevalence of adenomyosis ranges from 5 to 70%. The disease affects 2 in 10 women under the age of 40 years, while the incidence rises to 8 in 10 women between the ages of 40 and 50 years. However, the incidence of adenomyosis is difficult to determine due to the lack of a unified definition and diagnostic criteria based on noninvasive diagnostic methods. Its detection rate in the population varies from 10 to 61% according to different authors.</italic></p> <p><italic>This paper presents surgical procedures for adenomyosis excision in the patient to perform her further reproductive function. Since 2012, by using the procedure described by H. Osada, the researchers (Prof. V.B. Tskhay and T.A. Makarenko, MD) of the Department of Obstetrics, Krasnoyarsk State Medical University, have been performing surgical interventions for excision of adenomyosis in patients with its diffuse forms and uterine sizes at 10 to 22 weeks’ gestation. The authors have also shown an original approach to suturing the uterus during surgery. The researchers (Prof. N.N. Rukhlyada and K.Yu. Krylov, PhD) of the Department of Obstetrics and Gynecology, Saint Petersburg State Pediatric Medical University, did 242 operations, of which 172 were performed to restore fertility; moreover, the total number of pregnancies that had occurred was 74 (43.1% or 30.5% of all the interventions).</italic></p> <p><bold><italic>Conclusion: </italic></bold><italic>Considering our experience of surgical interventions by laparotomy, we can conclude that there is no unified technique for the surgical treatment of adenomyosis – the choice of incisions and the way of suturing the myometrium depend both on the size of the uterus and on the location of the affected myometrium, its symmetry and uniformity, as well as on the volume of remaining intact tissue and the form of the defect.</italic></p></abstract><trans-abstract xml:lang="ru"><p><italic>Аденомиоз – разновидность доброкачественного патологического процесса, при котором ткань эндометриоза поражает мышечной слой матки. Главный принцип оперативного вмешательства – удаление ткани миометрия с инвазией эндометриоза. Распространенность аденомиоза колеблется от 5 до 70%. В возрасте до 40 лет заболевание поражает 2 из 10 женщин, тогда как между 40 и 50 годами заболеваемость возрастает до 8 из 10 женщин. Однако частоту возникновения аденомиоза установить сложно из-за отсутствия унифицированного определения и диагностических критериев, основанных на неинвазивных диагностических методах. Частота его выявления в популяции, по данным различных авторов, варьирует от 10 до 61%.</italic></p> <p><italic>В данной статье представлены хирургические методики иссечения аденомиоза с дальнейшим выполнением репродуктивной функции пациентки. Сотрудниками кафедры акушерского профиля КрасГМУ (проф. Цхай В.Б. и д.м.н. Макаренко Т.А.) с 2012 г. выполняются оперативные вмешательства по поводу иссечения аденомиоза по методике Х. Осада у пациенток с диффузными формами аденомиоза при размерах матки от 10 до 22 недель беременности. Также мы показали оригинальный подход к наложению швов на матку при оперативном вмешательстве. Сотрудниками кафедры акушерства и гинекологии СПбГПМУ (проф. Рухляда Н.Н. и к.м.н. Крылов К.Ю.) выполнены 242 операции, из которых 172 – с целью восстановления фертильности, при этом общее число наступивших беременностей составило 74 (43,1%, или 30,5% числа всех вмешательств).</italic></p> <p><bold><italic>Заключение:</italic></bold><italic> Учитывая наш опыт оперативных вмешательств методом лапаротомии, можно сделать вывод, что не существует единой техники при хирургическом лечении аденомиоза – выбор разрезов и способ ушивания миометрия зависят как от размеров матки, так и от особенностей расположения пораженного миометрия, его симметричности и равномерности, а также от объема остающейся здоровой ткани и формы дефекта.</italic></p></trans-abstract><kwd-group xml:lang="en"><kwd>adenomyosis</kwd><kwd>adenomyomectomy</kwd><kwd>laparoscopy</kwd><kwd>laparotomy</kwd><kwd>pregnancy</kwd><kwd>uterine rupture</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>аденомиоз</kwd><kwd>аденомиомэктомия</kwd><kwd>лапароскопия</kwd><kwd>лапаротомия</kwd><kwd>беременность</kwd><kwd>разрыв матки</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Strizhakov A.N., Davydov A.I., Pashkov V.M. 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