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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Obstetrics and Gynecology</journal-id><journal-title-group><journal-title xml:lang="en">Obstetrics and Gynecology</journal-title><trans-title-group xml:lang="ru"><trans-title>Акушерство и гинекология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0300-9092</issn><issn publication-format="electronic">2412-5679</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">593368</article-id><article-id pub-id-type="doi">10.18565/aig.2023.203</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Reviews</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Обзоры</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Methods of compression hemostasis in the management of postpartum hemorrhage</article-title><trans-title-group xml:lang="ru"><trans-title>Методы компрессионного гемостаза в управлении рефрактерными послеродовыми кровотечениями</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7014-6492</contrib-id><name-alternatives><name xml:lang="en"><surname>Artymuk</surname><given-names>Natalya V.</given-names></name><name xml:lang="ru"><surname>Артымук</surname><given-names>Наталья Владимировна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dr. Med. Sci., Professor, Head of the Department of Obstetrics and Gynecology named after Prof. G.A. Ushakova, Kemerovo State Medical University, Ministry of Health of the Russian Federation</p></bio><bio xml:lang="ru"><p>д.м.н., профессор, заведующая кафедрой акушерства и гинекологии им. проф. Г.А. Ушаковой, Кемеровский государственный медицинский университет Министерства здравоохранения Российской Федерации</p></bio><email>artymuk@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5641-5246</contrib-id><name-alternatives><name xml:lang="en"><surname>Marochko</surname><given-names>Tatyana Y.</given-names></name><name xml:lang="ru"><surname>Марочко</surname><given-names>Татьяна Юрьевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD, Associate Professor of the Department of Obstetrics and Gynecology named after Prof. G.A. Ushakova, Kemerovo State Medical University, Ministry of Health of the Russian Federation</p></bio><bio xml:lang="ru"><p>к.м.н., доцент кафедры акушерства и гинекологии им. проф. Г.А. Ушаковой, Кемеровский государственный медицинский университет Министерства здравоохранения Российской Федерации</p></bio><email>marochko.2006.68@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7310-974X</contrib-id><name-alternatives><name xml:lang="en"><surname>Apresyan</surname><given-names>Sergey V.</given-names></name><name xml:lang="ru"><surname>Апресян</surname><given-names>Сергей Владиславович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dr. Med. Sci., Professor of the Department of Obstetrics and Gynecology, Patrice Lumumba Peoples’ Friendship University of Russia</p></bio><bio xml:lang="ru"><p>д.м.н., профессор кафедры акушерства и гинекологии, Российский университет дружбы народов им. Патриса Лумумбы</p></bio><email>sapresyan@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7099-4405</contrib-id><name-alternatives><name xml:lang="en"><surname>Artymuk</surname><given-names>Dmitry A.</given-names></name><name xml:lang="ru"><surname>Артымук</surname><given-names>Дмитрий Анатольевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>clinical resident of the Department of Obstetrics and Gynecology, Patrice Lumumba Peoples’ Friendship University of Russia</p></bio><bio xml:lang="ru"><p>клинический ординатор кафедры акушерства и гинекологии, Российский университет дружбы народов им. Патриса Лумумбы</p></bio><email>martynych98@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Kemerovo State Medical University, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Кемеровский государственный медицинский университет» Минздрава России, кафедра акушерства и гинекологии имени профессора Г.А. Ушаковой</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Peoples’ Friendship University of Russia</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы», Медицинский институт</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2023-12-30" publication-format="electronic"><day>30</day><month>12</month><year>2023</year></pub-date><issue>12</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>16</fpage><lpage>24</lpage><history><date date-type="received" iso-8601-date="2023-09-21"><day>21</day><month>09</month><year>2023</year></date><date date-type="accepted" iso-8601-date="2023-09-21"><day>21</day><month>09</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2023, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2023, ООО «Бионика Медиа»</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/0300-9092/article/view/593368">https://journals.eco-vector.com/0300-9092/article/view/593368</self-uri><abstract xml:lang="en"><p>The incidence of postpartum hemorrhage (PPH) in the world is currently about 5% and has no tendency to decrease. Most maternal deaths associated with PPH are preventable. The patients respond appropriately to first-line treatments for PPH, which include uterotonics, uterine massage, and tranexamic acid; however, 10–20% of these patients remain refractory and require the use of second-line interventions. In case of severe refractory PPH, the patient often undergoes an emergency hysterectomy, which leads to loss of reproductive and menstrual functions, but to date it remains an urgent surgical intervention aimed at saving the life of a mother with uncontrolled bleeding.</p> <p>The article presents the historical aspects of the problem and overview of the current data on the management of refractory PPH with the use of compression methods, including compression measures (compression of the aorta or bimanual compression of the uterus), intrauterine balloon tamponade, endovascular methods (temporary balloon occlusion and embolization), ligation and temporary vascular occlusion using tourniquet hemostasis. Each of the methods has indications, contraindications, conditions, limitations, complications and effectiveness. The choice of the hemostasis method is known to depend on the preferences of the surgeon and the equipment of the clinics. Each of these methods can be used alone or in combination with other methods. However, conservative measures for preserving the uterus are acceptable only in a situation of hemodynamic stability of the patient when there is no life-threatening bleeding.</p> <p><bold>Conclusion:</bold> The problem of management of refractory PPH continues to be relevant at the present time. Various methods of compression hemostasis have been approved and they are successfully used alone or in combination with each other. However, there is a lack of data on their most rational sequence, combination with each other and with other methods. It is necessary to continue research in this direction.</p></abstract><trans-abstract xml:lang="ru"><p>В настоящее время частота послеродовых кровотечений (ПРК) в мире составляет около 5% и не имеет тенденции к снижению. Большинство случаев материнской смертности, связанной с ПРК, можно предотвратить. Наиболее часто пациентки с ПРК адекватно реагируют на методы лечения первой линии, которые включают утеротоники, массаж матки и транексамовую кислоту, однако 10–20% этих пациенток остаются рефрактерными, что требует использования вмешательств второй линии. При возникновении массивных рефрактерных ПРК нередко выполняется экстренная гистерэктомия, которая приводит к потере репродуктивной и менструальной функций, но до настоящего времени остается неотложным оперативным вмешательством, которое направлено на спасение жизни родильницы при неконтролируемом кровотечении.</p> <p>В статье представлены исторические аспекты проблемы и обзор современных данных по вопросу управления рефрактерными ПРК с применением компрессионных методов, включая компрессионные мероприятия (сдавление аорты или бимануальную компрессию матки), внутриматочную баллонную тампонаду, эндоваскулярные методы (временную баллонную окклюзию и эмболизацию), перевязку и временную окклюзию сосудов с применением турникетного гемостаза. Каждый из методов имеет показания, противопоказания, условия, ограничения, осложнения и эффективность. Общепризнано, что выбор метода гемостаза зависит от предпочтений хирурга и оснащения клиник. Каждый из этих методов может применяться как самостоятельно, так и в комплексе с другими методами. Однако консервативные меры по сохранению матки допустимы только в ситуации гемодинамической стабильности пациентки при отсутствии опасного для жизни кровотечения.</p> <p><bold>Заключение: </bold>В настоящее время проблема управления рефрактерными ПРК продолжает оставаться актуальной. Одобрены различные методы компрессионного гемостаза, которые успешно применяются как изолированно, так и в сочетании друг с другом. Однако данных о наиболее рациональной их последовательности, комбинации между собой и с другими методами недостаточно. Необходимы дальнейшие исследования в этом направлении.</p></trans-abstract><kwd-group xml:lang="en"><kwd>postpartum hemorrhage</kwd><kwd>complex compression hemostasis</kwd><kwd>controlled balloon tamponade</kwd><kwd>compression suture</kwd><kwd>devascularization</kwd><kwd>uterine artery embolization</kwd><kwd>uterine vascular ligation</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>послеродовое кровотечение</kwd><kwd>комплексный компрессионный гемостаз</kwd><kwd>управляемая баллонная тампонада</kwd><kwd>компрессионный шов</kwd><kwd>деваскуляризация</kwd><kwd>эмболизация маточных артерий</kwd><kwd>перевязка маточных сосудов</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Баринов С.В., Медянникова И.В., Тирская Ю.И., Кадцына Т.В., Надежина Е.С., Лазарева О.В., Ковалева Ю.А., Гребенюк О.А., Раздобедина И.Н. 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