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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Obstetrics and Gynecology</journal-id><journal-title-group><journal-title xml:lang="en">Obstetrics and Gynecology</journal-title><trans-title-group xml:lang="ru"><trans-title>Акушерство и гинекология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0300-9092</issn><issn publication-format="electronic">2412-5679</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">625920</article-id><article-id pub-id-type="doi">10.18565/aig.2023.285</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Guidelines for the Practitioner</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>В помощь практическому врачу</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Intimate hygiene in patients with genital itching and dryness</article-title><trans-title-group xml:lang="ru"><trans-title>Интимная гигиена у пациенток с зудом и сухостью половых органов</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4111-6670</contrib-id><name-alternatives><name xml:lang="en"><surname>Chernova</surname><given-names>Nadezhda I.</given-names></name><name xml:lang="ru"><surname>Чернова</surname><given-names>Надежда Ивановна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dr. Med. Sci., Head of the Department of Anogenital Dermatosis and Sexually Transmitted Infections, Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology</p></bio><bio xml:lang="ru"><p>д.м.н., руководитель отдела аногенитальных дерматозов и инфекций, передаваемых половым путем, Московский научно-практический центр дерматовенерологии и косметологии ДЗМ</p></bio><email>d.chernova@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7291-3149</contrib-id><name-alternatives><name xml:lang="en"><surname>Zadorozhnaya</surname><given-names>Irina S.</given-names></name><name xml:lang="ru"><surname>Задорожная</surname><given-names>Ирина Сергеевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD, Junior Researcher of the Department of Anogenital Dermatosis and Sexually Transmitted Infections, Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology</p></bio><bio xml:lang="ru"><p>к.м.н., м.н.с. отдела аногенитальных дерматозов и инфекций, передаваемых половым путем, Московский научно-практический центр дерматовенерологии и косметологии ДЗМ</p></bio><email>d.zadorozhnayais@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9571-1512</contrib-id><name-alternatives><name xml:lang="en"><surname>Proskurina</surname><given-names>Maria I.</given-names></name><name xml:lang="ru"><surname>Проскурина</surname><given-names>Мария Игоревна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>dermatovenereologist, Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology</p></bio><bio xml:lang="ru"><p>врач-дерматовенеролог, Московский научно-практический центр дерматовенерологии и косметологии ДЗМ</p></bio><email>mariapro425@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Moscow Scientific and Practical Center for Dermatovenerology and Cosmetology, Moscow Healthcare Department</institution></aff><aff><institution xml:lang="ru">ГБУЗ города Москвы «Московский научно-практический центр дерматовенерологии и косметологии Департамента здравоохранения города Москвы»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2023-12-30" publication-format="electronic"><day>30</day><month>12</month><year>2023</year></pub-date><issue>12</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>190</fpage><lpage>196</lpage><history><date date-type="received" iso-8601-date="2024-01-23"><day>23</day><month>01</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2024-01-23"><day>23</day><month>01</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2023, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2023, ООО «Бионика Медиа»</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/0300-9092/article/view/625920">https://journals.eco-vector.com/0300-9092/article/view/625920</self-uri><abstract xml:lang="en"><p>The article presents the data which are available in the modern literature on the possibilities for patients with itching and dryness of the vulva to use cleansers. Washing the skin without special products is not effective enough as most biological contaminants are poorly soluble in water. The type, concentration, combination of surfactant with other components, its washability and pH can significantly affect the epidermal barrier and lead to transdermal water loss, dryness, skin irritation in healthy people and worsening of symptoms in patients with skin problems. Therefore, it is extremely important to understand these differences in order to determine the most appropriate cleanser for each situation. There are two most common types of cleansers: natural soaps and synthetic detergents (syndets). According to scientific studies, syndets can effectively maintain the natural structure, function and integrity of the skin, whereas natural soaps tend to negatively affect the skin and cause an impairment of the protective epidermal barrier, dissolution of lipids and pH changes, which can lead to dryness, itching and imbalance of microbial composition. The article covers the advantages and disadvantages of soap-based products and synthetic cleansers.</p> <p><bold>Conclusion:</bold> In order to preserve the health of the vulva and eliminate and/or reduce existing complaints and symptoms in patients with pathological conditions, it is important to use specialized detergents that are soft in nature, highly effective, and have minimal effect on the stratum corneum. The products of Ginocomfort® line have such properties and are able to restore the hydro-lipid layer of the epidermis, reduce itching, dryness and inflammation; they can moisturize, saturate and retain fatty components.</p></abstract><trans-abstract xml:lang="ru"><p>В статье приведены данные, имеющиеся в современной литературе, о возможностях применения очищающих средств у пациенток с зудом и сухостью вульвы. Поскольку большинство биологических загрязнений плохо растворяется в воде, мытье кожи без специальных средств будет недостаточно эффективным. Тип, концентрация, комбинация поверхностно-активного вещества с другими компонентами, его смываемость и pH могут значительно влиять на эпидермальный барьер, приводя к трансдермальной потере воды, ощущению сухости, раздражению кожи у здоровых людей и усугублению симптомов у пациентов с проблемами кожи. В связи с чем чрезвычайно важно понимать эти различия, чтобы определить наиболее подходящее очищающее средство для каждой ситуации. Наиболее часто применяются очищающие средства двух типов: натуральные мыла и синтетические моющие средства (или синдеты). Научными исследованиями показано, что последние могут эффективно поддерживать естественную структуру, функцию и целостность кожи, тогда как первые имеют тенденцию отрицательно влиять на кожу, вызывая нарушение защитного эпидермального барьера, растворение липидов и изменение pH, что способно приводить к сухости и зуду, дисбалансу микробного состава. В статье рассмотрены преимущества и недостатки средств на основе мыла и синтетических очищающих средств.</p> <p><bold>Заключение:</bold> В результате было показано, что для сохранения здоровья вульвы и устранения и/или уменьшения уже имеющихся жалоб и симптомов при патологических состояниях важно применение мягких по своей природе, высокоэффективных, оказывающих минимальное воздействие на роговой слой специализированных моющих средств. Такими свойствами обладают средства линейки «Гинокомфорт», способные восстанавливать гидролипидный слой эпидермиса, уменьшать зуд, сухость, воспаление, увлажнять, насыщать и удерживать жировые компоненты.</p></trans-abstract><kwd-group xml:lang="en"><kwd>intimate hygiene</kwd><kwd>dryness and itching of the vulva</kwd><kwd>cleansing detergents</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>интимная гигиена</kwd><kwd>сухость и зуд вульвы</kwd><kwd>очищающие моющие средства</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Farage M.A., Maibach H.I. Tissue structure and physiology of the vulva. The vulva: anatomy, physiology and pathology. New York: Informa Healthcare. 2016: 9-26.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Mathias C.G., Maibach H.I. Dermatotoxicology monographs I. Cutaneous irritation: factors influencing the response to irritants. Clin. 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