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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Obstetrics and Gynecology</journal-id><journal-title-group><journal-title xml:lang="en">Obstetrics and Gynecology</journal-title><trans-title-group xml:lang="ru"><trans-title>Акушерство и гинекология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0300-9092</issn><issn publication-format="electronic">2412-5679</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">716455</article-id><article-id pub-id-type="doi">10.18565/aig.2025.361</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Reviews</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Обзоры</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Intrauterine pathology in women of reproductive age: a focus on the tubal angles</article-title><trans-title-group xml:lang="ru"><trans-title>Внутриматочная патология в репродуктивном возрасте: фокус на трубные углы матки</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1098-0546</contrib-id><name-alternatives><name xml:lang="en"><surname>Petrova</surname><given-names>Oksana P.</given-names></name><name xml:lang="ru"><surname>Петрова</surname><given-names>Оксана Павловна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Аpplicant at the Department of Obstetrics, Gynecology and Perinatology No. 1, obstetrician-gynecologist</p></bio><bio xml:lang="ru"><p>врач акушер-гинеколог, соискатель кафедры акушерства, гинекологии и перинатологии № 1</p></bio><email>petrovka_71@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2671-6985</contrib-id><name-alternatives><name xml:lang="en"><surname>Sulima</surname><given-names>Anna N.</given-names></name><name xml:lang="ru"><surname>Сулима</surname><given-names>Анна Николаевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dr. Med. Sci., Professor at the Department of Obstetrics, Gynecology and Perinatology No. 1</p></bio><bio xml:lang="ru"><p>д.м.н., профессор кафедры акушерства, гинекологии и перинатологии № 1</p></bio><email>gsulima@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Order of the Labor Red Banner Medical Institute named after S.I. Georgievsky of V.I. Vernadsky Сrimean Federal University</institution></aff><aff><institution xml:lang="ru">Ордена Трудового Красного Знамени Медицинский Институт имени С.И. Георгиевского ФГАОУ ВО «Крымский федеральный университет имени В.И. Вернадского»</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Harmonia Med LLC</institution></aff><aff><institution xml:lang="ru">ООО «ГАРМОНИЯ МЕД»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2026-07-17" publication-format="electronic"><day>17</day><month>07</month><year>2026</year></pub-date><issue>6</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>31</fpage><lpage>36</lpage><history><date date-type="received" iso-8601-date="2026-07-15"><day>15</day><month>07</month><year>2026</year></date><date date-type="accepted" iso-8601-date="2026-07-15"><day>15</day><month>07</month><year>2026</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2026, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2026, ООО «Бионика Медиа»</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/0300-9092/article/view/716455">https://journals.eco-vector.com/0300-9092/article/view/716455</self-uri><abstract xml:lang="en"><p>Intrauterine pathology is one of the leading causes of reproductive dysfunction in women. According to the literature, 25% to 50% of cases of infertility, miscarriage, and abnormal uterine bleeding are associated with organic pathology of the uterine cavity. The tubal angles of the uterus are one of the key, yet underestimated, areas where local changes can significantly affect women’s reproductive health.</p> <p>This review analyzes and summarizes the existing literature on intrauterine pathology localized in the tubal angles. The multifactorial pathogenetic mechanisms underlying the development of tubal angle pathology are studied and described. Most of the studies conducted from 2018 to 2025 provide the overall incidence of the pathology or demonstrate individual case series describing localization in the angles, but do not present systematic statistics. The diagnosis and differentiation of tubal angle pathology are of significant clinical importance for preserving women’s reproductive health and fertility, as well as for the timely treatment of precancerous endometrial lesions. This paper reviews diagnostic techniques, describing the stages involved and the significance of each in clinical practice.</p> <p><bold>Conclusion.</bold> The tubal angles of the uterus are an underrecognized region where local changes, combined with systemic factors, significantly influence not only the development of intrauterine pathology but also fertility and pregnancy outcomes. The current situation requires a detailed study of the morphological structure and functional characteristics of this region, the identification of potential predictors, and the subsequent development of diagnostic criteria and strategies to prevent recurrence.</p></abstract><trans-abstract xml:lang="ru"><p>Внутриматочная патология – одна из ведущих причин нарушения репродуктивной функции женщин. По данным литературы, от 25 до 50% случаев бесплодия, невынашивания беременности, аномальных маточных кровотечений связаны с органической патологией полости матки. Трубные углы матки – одна из ключевых, но недооцененных зон, где локальные изменения могут существенно влиять на репродуктивное здоровье женщин.</p> <p>В настоящем обзоре проанализированы и обобщены существующие литературные данные по внутриматочной патологии, локализованной в трубных углах. Изучены и описаны многофакторные патогенетические механизмы формирования патологии в трубных углах матки. Большинство проанализированных работ за период 2018–2025 гг. дают общую частоту нозологий или приводят отдельные серии с описанием локализации в углах, но без представления систематизированной статистики. Диагностика и дифференциация патологии в трубных углах имеют важное клиническое значение в сохранении репродуктивного здоровья и фертильности женщины, а также для своевременного лечения предраковых заболеваний эндометрия. Рассмотрены диагностические методики с описанием этапности и значимости каждой из них в клинической практике.</p> <p><bold>Заключение. </bold>Трубные углы матки – недооцененный регион, где локальные изменения в сочетании с системными факторами существенно влияют не только на формирование внутриматочной патологии, но и на фертильность и исход беременности. Сложившаяся ситуация требует детального изучения морфологической структуры, функциональных особенностей данной области, поиска возможных предикторов с последующим формированием критериев диагностики и разработкой стратегии по предупреждению рецидива.</p></trans-abstract><kwd-group xml:lang="en"><kwd>tubal angles</kwd><kwd>interstitial portion of the fallopian tube</kwd><kwd>organic intrauterine pathology</kwd><kwd>reproductive age</kwd><kwd>diagnosis</kwd><kwd>management</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>трубные углы матки</kwd><kwd>интерстициальный отдел маточной трубы</kwd><kwd>органическая внутриматочная патология</kwd><kwd>репродуктивный возраст</kwd><kwd>диагностика</kwd><kwd>тактика ведения</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Bonne S., Pouget O., Rongieres C. Fisiología de la trompa. 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