REPRODUCTIVE FUNCTION REALIZATION IN PATIENTS WITH PRIMARY GONADAL ESTROGEN DEFICIENCY


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Abstract

Objective. To study the possibilities of realizing the reproductive function in patients with primary gonodal dysgenesis in different karyotype. Subjects and methods. Six patients with primary gonodal dysgenesis (4 with Swyer syndrome and 2 with Turner’s syndrome) who underwent clinical, laboratory, echographic, densitometric monitoring, in vitro fertilization and embryo transfer were examined. Results. There were reports on 6 cases with successful reproductive function realization due to assisted reproductive technologies using donor oocytes in patients with different clinical forms of primary gonadal estrogen deficiency, such as Swyer syndrome and Turner’s syndrome. Conclusion. Reproductive function can be realized in this group of patient years when applying a comprehensive and multidisciplinary approach to managing patients with primary gonodal estrogen deficiency since early adolescence.

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About the authors

I. P BELOKON

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia

E. V UVAROVA

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia

Email: elena-uvarova@yandex.ru

I. A KISELEVA

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia

K. A YAVOROVSKAYA

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia

Z. S KHODZHAYEVA

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia

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