Clinical evaluation of the efficiency and safety of topical treatment for bacterial vaginosis in pregnant women
- Authors: Logutova L.S.1, Novikova S.V.1, Tsivtsivadze E.B.1, Fedotova A.V.1
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Affiliations:
- Moscow Regional Research Institute of Obstetrics and Gynecology
- Issue: No 10 (2015)
- Pages: 91-96
- Section: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/247544
- ID: 247544
Cite item
Open Access
Access granted
Abstract
Objective. To evaluate the efficacy and safety of Multi-Gyn-ActiGel used to treat bacterial vaginosis (BV) and to prevent its recurrences in pregnant women before labor. Subjects and methods. A study group included 50 pregnant women with threatened preterm labor and new-onset BV. A comparison group consisted of 30 pregnant women with BV who had been treated with metronidazole and clindamycin 3 months before hospitalization. All underwent clinical and laboratory examinations. During BV therapy, Group 1 received Multi- Gyn-ActiGel and Group 2 used a probiotic. Results. Multi- Gyn-ActiGel was proved efficient and safe in treating BV and preventing obstetric complications. During therapy with this drug, the patients had no complaints and achieved optimal pH values and the normal pattern of vaginal smears. In the study group, all the pregnant women delivered at term. Conclusion. Multi-Gyn-ActiGel is an effective medication to treat BV and to prevent its recurrences. It is safe for a fetus and may be used in pregnant women at early gestational ages when a decision is made on the most effective prevention of pregnancy and labor complications.
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About the authors
Lydia S. Logutova
Moscow Regional Research Institute of Obstetrics and GynecologyMD, Professor, Deputy Director for Science
Svetlana V. Novikova
Moscow Regional Research Institute of Obstetrics and Gynecology
Email: sv_novikova@list.ru
MD, head of the obstetrics observational department
Ekaterina B. Tsivtsivadze
Moscow Regional Research Institute of Obstetrics and GynecologyMD, Ph.D., a researcher of obstetric observational department
Alla V. Fedotova
Moscow Regional Research Institute of Obstetrics and GynecologyPhD, researcher of the obstetrics observational department
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