OVARIAN GERM CELL TUMORS: CURRENT DIAGNOSTIC APPROACHES


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Abstract

Objective. To carry out a systematic analysis of the data available in the current literature on the diagnosis of ovarian germ cell tumors (OGCT). Material and methods. The review included the data of foreign and Russian papers published in the past 10 years and found in Pubmed on this topic. Results. The authors describe the current possibilities of up-to-date informative diagnostic imaging techniques used in clinical practice, such as ultrasonography, magnetic resonance imaging, and computed tomography; the most informative algorithms for comprehensive examination, which allows for a high degree of reliability in diagnosing OGCT, in estimating the extent to which the latter spread to the nearby tissues and organs, in detecting regional and distant metastases, by optimizing their staging in the presence of malignant tumors which in turn determines optimal treatment choice and improves prognosis. They also show the role of tumor markers in the differential diagnosis of OGST. Conclusion. The correct choice of a set of diagnostic studies is crucial for the adequate differential diagnosis of ovarian masses and for the adequate staging of malignant germ cell tumors, which permits one to optimize management tactics in this group of patients.

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About the authors

Alina Evgen’evna Solopova

Email: dr.solopova@mail.ru
Candidate of Medicine, assistant professor, Department of radiology and radiotherapy, Faculty of Medicine, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia 119991, Russia, Moscow, Bolshaya Pirogovskaya str. 2, bld. 4

Yulia Nikolaevna Sologub

second-year resident, Department of Obstetrics and Gynecology, Faculty of Preventive Medicine I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia. 119991, Russia, Moscow, Bolshaya Pirogovskaya str. 2, bld. 4

Aleksandr Davidovich Makatsariya

Doctor of Medicine, Professor, Head of Department of Obstetrics and Gynecology, Faculty of Preventive Medicine, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia 119991, Russia, Moscow, Bolshaya Pirogovskaya str. 2, bld. 4

Sergey Konstantinovich Ternovoy

Doctor of Medicine, Professor, Head of Department of radiology and radiotherapy, Faculty of Medicine, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia. 119991, Russia, Moscow, Bolshaya Pirogovskaya str. 2, bld. 4

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