The status of biocenosis in pregnant women with a history of recurrent miscarriage

Objective. To study the vaginal microbiocenosis in pregnant women with a habitual miscarriage in history with the use of various diagnostic methods. Material and methods. A retrospective study included an analysis of outpatient records of 36 patients aged 28-46 years old, the average age was 36.9 ± 0.4 years, who applied for miscarriage in 2015-2017. Results. 30 women (83.3 %) did not complain during pregnancy, but noticed that the amount of discharge from the genital tract increased slightly. In the first trimester, bacterial vaginosis was detected in 7 (19.4%), in the second -in 12 (33.3%), in the third - in 13 (36.1%) women. In the third trimester, aerobic vaginitis (IUSTIcriteria, 2018) was also detected in 2 pregnant women in combination with bacterial vaginosis and Candida albicans of the genus. In patients with an established diagnosis of bacterial vaginosis, aerobic vaginitis in combination with candidiasis clindacin B prolong was prescribed. Conclusion. In women with habitual miscarriage, pregnancy is often complicated by a violation of the vaginal biocenosis with the active growth of Candida spp. or without it. A comparative description of the results of smears on microflora, gonococci, trichomonads, and real-time PCR showed that it is a mistake to judge the state of the biocenosis only by the results of the description of smears.

pregnancy, biocenosis, clindamycin, butoconazole