Preeclampsia: contemporary concepts of its pathogenesis
- Authors: Boris D.A.1, Shmakov R.G.1
-
Affiliations:
- Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia
- Issue: No 12 (2022)
- Pages: 12-17
- Section: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/250225
- DOI: https://doi.org/10.18565/aig.2022.213
- ID: 250225
Cite item
Abstract
The review analyzes Russian and foreign literature sources on the pathogenesis of preeclampsia. The latter is considered to be an urgent and unsolved problem in modern obstetrics. The wide prevalence, the complexity of etiopathogenesis, the lack of accurate and highly informative methods for prediction and diagnosis, as well as the insufficient effectiveness of therapeutic and preventive measures are a cause of higher global maternal and perinatal morbidity and mortality rates of preeclampsia. Understanding the pathogenetic mechanisms implicated in the development and progression of preeclampsia is of fundamental importance and plays an important role in specifying the causes of this pregnancy complication, which should be treated. Conclusion: Based on the analysis of the data available in the literature, the authors summarize the current aspects of the development and progression of preeclampsia.
Keywords
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About the authors
Daiana A. Boris
Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia
Email: dayana_boris@mail.ru
PhD, Researcher
Roman G. Shmakov
Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia
Email: r_shmakov@oparina4.ru
Dr. Med. Sci, Professor of the Russian Academy of Sciences, Director of the Institute of Obstetrics
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