ASSESSMENT OF THE RELATIONSHIP BETWEEN CERVICAL INTRAEPITHELIAL NEOPLASIA GRADE AND FEMALE AGE

Objective. To estimate the pattern of newly detected cervical intraepithelial neoplasia (CIN) cases in relation to the age of Omsk women. Subject and methods. A descriptive observational epidemiological study of found CIN cases was conducted in the women regionally attached to this health clinic for service, by using the primary records of Omsk Women’s Health Clinic One over 2002 to 2012. Results. There was a substantial change in the age structure of CIN towards a predominance of the disease in patients aged 18-35 years (increase rate = + 11.3; p < 0.001) as compared to those at an older age; a correlation between the grade of CIN and the women’s age (p < 0.001); a direct relationship between the grade of CIN and the patients’ age (p < 0.001). Grade I CIN was prevalent in women of reproductive age and Grade II CIN was in those over 50 years, (p < 0.001). Despite the trend towards a decrease in CIN II(decrease rate = -7.0;p < 0.001) and CIN III (decrease rate = -3.0; p < 0.05) in the past decade (from visit rates), there was a considerable proportion of CIN III in patients aged 18-35 (10.5%), 36-49 (22.9%), and over 50 (26.6%) years. Conclusion. The findings suggest that the epidemiological situation of CIN substantially changed in the study period.

CIN, cervix of the uteri, cervical intraepithelial neoplasia, age, mortality