Possibilities of argon plasma coagulation in the combination therapy of severe endometriosis

Objective. To assess a combination of surgery and drug, antirecurrent therapy for severe genital endometriosis. Subject and methods. Fifty-nine patients with severe genital endometriosis were examined. Group 1 included 33 women whose surgical treatment used argon plasma coagulation (APC) in combination with dienogest 2 mg as antirecurrent therapy; Group 2 comprised 11 patients who received APC during surgery and antirecurrent therapy with gonadotropin-releasing hormone (GnRH) agonists; Group 3 consisted of women operated on by conventional procedures without APC, followed by therapy with GnRH agonists. Results. Groups 1 and 2, as compared to Group 3, exhibited a significant reduction in pain syndrome and in the postoperative adhesion formation process verified by relaparoscopy. Conclusion. With APC, followed by therapy with dienogest (visanne), the conception rate is 1.5-fold higher than that with standard energies, followed by therapy with GnRH agonists.

endometriosis, argon plasma coagulation