EFFICACY OF MICRONIZED PROGESTERONE-CONTAINING TRANSDERMAL GEL IN THE TREATMENT OF FIBROCYSTIC MASTOPATHY: RESULTS OF A RUSSIAN STUDY


Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

Objective. To evaluate the effect of progestogel as monotherapy on quality of life and magnitude of pain syndrome in fibrocystic mastopathy (FMP). Subjects and methods. The time course of changes in its symptoms was estimated using the pain visual analogue scale (VAS), the SF-6 health survey questionnaire, and ultrasonography in 798patients diagnosed with FMP. Results. The pain VAS scores were 5.7 (5.0; 7.0) at baseline and statistically significantly lower [(2.4 (1.0; 4.0)] and [1.0 (0.0; 2.0)] after 3 and 6 months, respectively (p<0.05). The rate of diffuse and nodular changes was decreased by 44.3 and 60.4%, respectively. That of cystic masses ≥ 10 mm or less was reduced by 61.8 and 4.3%, respectively. There were physical and emotional improvements. Conclusion. Three-month progestogel monotherapy for FMP contributes to a decline in the number and extent of cystic changes, significantly reduces the magnitude of pain syndrome, and improves the quality of physical and mental health.

Толық мәтін

Рұқсат жабық

Авторлар туралы

Elena Andreeva

Email: endogin@mail.ru
MD, Head of the medical-diagnostic department of endocrine gynecology, Endocrinology Research Center, Ministry of Health of Russia, Professor of the Department of Reproductive Medicine and Surgery, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia 115478, Russia, Moscow, Moskvorechie str. 1

Nadezhda Rozhkova

Email: 2013rozhkova@gmail.com
MD, Professor, Honored Scientist of Russia, winner of the USSR Council of Ministers Prize, director of the National Center of Oncology of Reproductive Organs, P.A. Herzen MNIOI, Ministry of Health of Russia; Professor, Department of Clinical mammology, radiation diagnosis and radiotherapy, Peoples Friendship University of Russia, President of the Russian Radiology Association, President of the Russian Mammologists Association, President of NGO Association “Mammalogy”, chairman of the section Women’s Radiology MOMP, a member of the Committee for European Radiology Association. 125284, Russia, Moscow, 2nd Botkinsky per. 3

Әдебиет тізімі

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