A new hematological marker for intrauterine sepsis associated with preterm labor and premature rupture of membranes


Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

Aim. To determine the role of mean platelet volume (MPV) in a complete blood count (CBC) in pregnant women with premature rupture of membranes for predicting intrauterine neonatal sepsis. Materials and methods. A retrospective study was conducted. It included the analysis of 84 birth histories of patients with a single pregnancy, who were admitted to Perinatal Center of Rostov region in the periodfrom 2017 to occurred before 31.0 weeks of gestation. All patients included in the study were treated and diagnosed according to the Protocol for preterm birth management. Additionally, MPV in a complete blood count in pregnant women was assessed. The course of the neonatal period of life in newborns was analyzed as well. Other platelet-related indicators were not covered in this article. This issue is subject to consideration in further articles. At present, the analysis of changes in other characteristics of platelets in this group of pregnant women and the analysis of neonatal outcomes are being carried out. Results. Comparison of median values of MPV showed statistically signif icant differences between pregnant women in group I (Me=9.5; Q1=8.3, Q3=10.1) and in group II (Me=6.3; Q1=5.4, Q3= 7.8) (p<0.001). Statistically, the MPV value in a complete blood count before delivery was significantly higher in women, whose babies were born with sepsis compared to the group of women, whose premature babies were born without neonatal sepsis. Conclusion. High MPV in a complete blood count in pregnant women with premature rupture of membranes before delivery is a marker for the sepsis diagnosis in premature babies.

Толық мәтін

Рұқсат жабық

Авторлар туралы

Natalia Kuznetsova

Rostov State Medical University, Ministry of Health of the Russian Federation; Clinic of Professor Bushtyreva

Email: lauranb@inbox.ru
Dr. Med. Sci., Professor at the Simulation Training Center

Irina Bushtyreva

Clinic of Professor Bushtyreva

Email: kio4@mail.ru
Dr. Med. Sci., Professor, Director

Viktor Chernavsky

Rostov State Medical University, Ministry of Health of the Russian Federation; Perinatal Center of Rostov region

Email: chrnv@mail.ru
Cand. Med. Sci., Associate Professor of the Department of Obstetrics and Gynecology No. 2

Maria Dmitrieva

Rostov State Medical University, Ministry of Health of the Russian Federation; Perinatal Center of Rostov region

Email: dr.dmitrieva@inbox.ru
Junior researcher

Anton Baranov

Rostov State Medical University, Ministry of Health of the Russian Federation; Perinatal Center of Rostov region

Email: a.p.baranov@mail.ru
post-graduate student, Simulation Training Center

Әдебиет тізімі

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