PREGRAVID PREPARATION IN NONSPECIFIC INFLAMMATORY PROCESSES OF EXTERNAL GENITALS

Objective. To evaluate the eff icacy and tolerance of hexicon used for the pregravid preparation of women with nonspecific inflammatory processes of external genitals. Subjects and methods. Sixty women with nonspecif ic inflammatory processes of external genitals were followed up. Group 1 included 30 patients who were found to have less than 50 leukocytes through microscopic study of the vaginal contents. Group 2 comprised 30 patients who had microscopically more than 50 leukocytes in the smears. All the patients used hexicon vaginal suppositories 16 mg twice daily for 10 days. Examinations were made before treatment, on day 5 of its initiation, and 3 and 30 days after its termination. The vaginal microflora was microscopically and culturally examined. Results. The investigation showed a significant normalization of white blood cell count in the vaginal and cervical secretions and local immunity parameters in the women of the two groups after treatment performed. Conclusion. Hexicon is effective and safe at the stage of pre-conceptional preparation for desired pregnancy. At the same time, the result of treatment does not depend on the pretreatment level of leukocytosis in the vaginal smear.

pregravid preparation, nonspecific inflammatory processes of external genitals, pregnancy