USE OF COMPRESSION PRODUCTS IN THERAPY FOR CHRONIC VENOUS INSUFFICIENCY AND IN THE PREVENTION OF THROMBOEMBOLIC EVENTS IN PREGNANT WOMEN

Objective. to evaluate the safety and clinical efficacy of VENOTEKS compression knitted fabric (tights for pregnant women and antiembolic stockings for patients with varicosity) and a high patient compience versus those of elastic bandages. Subjects and methods. An open comparative randomized prospective clinical trial was conducted in 45 pregnant women with chronic venous insufficiency at the V.F. Snegirev Clinic of Obstetrics and Gynecology, I.M. Sechenov First Moscow State Medical University. Clinical, laboratory, and instrumental studies were performed. Results: During a follow-up, the patients using the compression knitted fabric were found to have a significant regression of symptoms, such as severity, pain, and cramps in the calf, parasthesias, edema, and fatigability as compared to the baseline level. As compared to therapy with elastic bandages, that with compression knitted fabric caused no statistically significant leg volume increase during the study. Ultrasound angioscanning with Doppler study showed a significant decrease in the diameter of the greater saphenous vein during compression knitted fabric therapy. There was no convincing evidence for hemostatic changes when compression products were worn. No thrombotic or thromboembolic events were detected in any of the cases, there were no adverse reactions or undesirable events either. Conclusion. The study showed the high clinical efficacy and safety of compression knitted fabric and high compliance when the patients used it in the treatment of chronic venous insufficiency and in the prevention of thrombotic events in pregnancy and postpartum.

compression knitted fabric, elastic bandages, pregnancy, chronic venous insufficiency