Advances and prospects for overcoming male infertility in assisted reproductive technology programs using different sperm selection procedures


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Objective. To make a systems analysis of the data available in the current literature on the impact of different current sperm selection procedures on the efficiency of assisted reproductive technology (ART) programs. Material and methods. The review included the data of Russian and foreign articles found in the Pubmed database on this topic and published in the past 10 years. Results. Current methods to assess the male genomic integrity and their prognostic value in the outcomes of ART programs are described. The impact of different current sperm selection procedures on the efficiency of ART programs is presented. Conclusion. It is necessary to conduct further investigations of the impact of different procedures to select sperm on the efficiency of ART programs and to estimate the prognostic value of sperm DNA fragmentation on the effectiveness of ART and pregnancy outcomes.

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作者简介

Alina Dudarova

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: kanshaov85@mail.ru
post-graduate, department of assistive technologies in the treatment of infertility

Veronica Smolnikova

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: veronika.smolnikova@mail.ru
MD, a leading researcher, department of assistive technologies in the treatment of infertility

Anastasia Zobova

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: a_zobova@oparina4.ru
PhD, researcher, Department of assistive technologies in the treatment of infertility

Natalya Makarova

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: np_makarova@oparina4.ru
PhD, Senior Scientist, department of assistive technologies in the treatment of infertility

Elena Kalinina

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: e_kalinina@oparina4.ru
MD, Head of the department of assistive technologies in the treatment of infertility

Maria Andreeva

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: a.g.andreeva@mail.ru
post-graduate, department of assistive technologies in the treatment of infertility

Zohra Naimi

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: naimi-zohra@mail.ru
post-graduate, department of assistive technologies in the treatment of infertility

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