THE NEPHRITIC MASK OF SYSTEMIC LUPUS ERYTHEMATOSUS IN A PREGNANT WOMAN AND THE BIRTH OF A BABY WITH NEONATAL LUPUS


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Background. Systemic lupus erythematosus (SLE) is an autoimmune rheumatic disease with a variety of clinical manifestations that frequently appear as a mask of various diseases. The kidneys are most commonly involved in the pathological process in SLE due to the ability to delay circulating immune complexes. Case report. The paper describes a clinical case of a nephritic mask of SLE in a pregnant woman and the birth of a baby with neonatal lupus. In the multigravida with a compromised history of pregnancy loss and early preeclampsia, who had long been followed up for chronic glomerulonephritis and hypertensive syndrome, there could be an successful outcome of twin pregnancy with the birth of viable newborns due to a thorough examination for SLE as a cause of nephritic syndrome. Conclusion. The establishment of the lupus etiology of glomerulonephritis, the presence of chronic kidney disease in the outcome of lupus nephritis concurrent with APS-associated nephropathy made it possible to optimize drug therapy and to successfully complete this pregnancy.

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作者简介

Tatiana Kirsanova

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: a_tatya@mail.ru
PhD, senior researcher of the Department of Reproductive Hematology and Clinical Hemostasis 117997, Russia, Moscow, Ac. Oparina str., 4

Zulfiya Khodzhaeva

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: zkhodjaeva@mail.ru
MD., Professor, Deputy Director of Obstetrics Institute 117997, Russia, Moscow, Ac. Oparina str., 4

Nataliya Kravchenko

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: n_kravchenko@oparina4.ru
PhD, senior researcher of Department of Obstetrics and Extra Genital Pathology 117997, Russia, Moscow, Ac. Oparina str., 4

Zafida Piliya

Academician V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: zaflda@mail.ru
graduate student of High Risk Pregnancy Department 117997, Russia, Moscow, Ac. Oparina str., 4

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