Value of embryonic mitochondrial DNA in predicting the effectiveness of assisted reproductive technologies
- 作者: Nepsha O.S.1, Kulakova E.V.1, Ekimov A.N.1, Drapkina Y.S.1, Makarova N.P.1, Kraevaya E.E.1, Kalinina E.A.1
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隶属关系:
- Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia
- 期: 编号 11 (2021)
- 页面: 125-134
- 栏目: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/249409
- DOI: https://doi.org/10.18565/aig.2021.11.125-134
- ID: 249409
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作者简介
Oksana Nepsha
Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia
Email: o_nepsha@oparina4.ru
PhD. (Biol. Sci.), Researcher at the BV. Leonov Department of Assisted Technologies for the Treatment of Infertility
Elena Kulakova
Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia
Email: e_kulakova@oparina4.ru
PhD, Senior Researcher, Professor BV. Leonov Department of IVF
Alexey Ekimov
Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia
Email: a_ekimov@oparina4.ru
doctor-laboratory geneticist, Head of the Group of preimplantation genetic screening of the Laboratory of Molecular Genetic Methods
Yulia Drapkina
Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia
Email: yu_drapkina@oparina4.ru
PhD, researcher, Professor BV. Leonov Department of IVF
Natalia Makarova
Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia
Email: np_makarova@oparina4.ru
Dr. Biol. Sci., Senior Researcher at the BV. Leonov Department of Assisted Technologies for the Treatment of Infertility
Elizaveta Kraevaya
Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia
Email: e_kraevaya@oparina4.ru
Ph.D., Junior Researcher at the BV. Leonov Department of Assisted Technologies for the Treatment of Infertility
Elena Kalinina
Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia
Email: e_kalinina@oparina4.ru
Dr. Med. Sci., Professor, Head of the BV. Leonov Department of Assisted Technologies for the Treatment of Infertility
参考
- World Health Organization. Sexual and reproductive health. 2020. Available at: https://www.who.int/reproductivehealth/topics/infertility/perspective/en/
- SART: Society for Reproductive Technology. National Summary Report. Final National Summary Report for 2016. Available at: https://wwwsartcorsonlinecom/rptCSR_PublicMultYearaspx?reportingYear=2016
- Gardner D.K., Schoolcraft W.B. In vitro culture of human blastocysts. In: Jansen R., Mortimer D., eds. Towards reproductive certainty: fertility and genetics beyond. Parthenon Press, Carnforth; 1999: 378-88.
- Bromer J.G., Ata B., Seli M., Lockwood C.J., Seli E. Preterm deliveries that result from multiple pregnancies associated with assisted reproductive technologies in the USA: a cost analysis. Curr. Opin. Obstet. Gynecol. 2011; 23(3): 168-73. https://dx.doi.org/10.1097/GCO.0b013e32834551cd.
- Timofeeva A.V., Chagovets V.V., Drapkina Yu.S., Makarova N.P., Kalinina E.A., Sukhikh G.T. Cell-free, embryo-specific sncRNA as a molecular biological bridge between patient fertility and IVF efficiency. Int. J. Mol. Sci. 2019; 20(12): 2912. https://dx.doi.org/10.3390/ijms20122912.
- Кулакова Е.В., Калинина Е.А., Трофимов Д.Ю., Макарова Н.П., Хечумян Л. Р., Дударова А.Х. Вспомогательные репродуктивные техно -логии у супружеских пар с высоким риском генетических нарушений. Преимплантационный генетический скрининг. Акушерство и гинекология. 2017; 8: 21-7. https://dx.doi.org/10.18565/aig.2017.8.21-7.
- Долгушина Н.В., Коротченко О.Е., Бейк Е.П., Абдурахманова Н.Ф., Ильина Е.О., Кулакова Е.В. Клинико-экономический анализ эффективности преимплантационного генетического скрининга у пациенток позднего репродуктивного возраста. Акушерство и гинекология. 2017; 11: 56-61. https: //dx.doi.org/10.18565/aig.2017.11.56-61.
- Tarn J.J., Garcia-Perez M.A., Hamatani T., Cano A. Infertility etiologies are genetically and clinically linked with other diseases in single metadiseases. Reprod. Biol. Endocrinol. 2015; 13: 31. https://dx.doi.org/10.1186/s12958-015-0029-9.
- Fragouli E., Spath K., Alfarawati S., Kaper F., Craig A., Michel C.-E. et al. Altered levels of mitochondrial DNA are associated with female age, aneuploidy, and provide an independent measure of embryonic implantation potential. PLoS Genet. 2015; 11(6): e1005241. https://dx.doi.org/10.1371/journal.pgen.1005241.
- Diez-Juan A., Rubio C., Marin C., Martinez S., Al-Asmar N., Riboldi M. et al. Mitochondrial DNA content as a viability score in human euploid embryos: less is better. Fertil. Steril. 2015; 104(3): 534-41.e1. https://dx.doi.org/0.1016/j.fertnstert.2015.05.022.
- Harvey A.J. Mitochondria in early development: linking the microenvironment, metabolism and the epigenome. Reproduction. 2019; 157(5): R159-R179. https://dx.doi.org/10.1530/REP-18-0431.
- Vaught R.C., Dowling D.K. Maternal inheritance of mitochondria: implications for male fertility? Reproduction. 2018; 155(4): R159-R168. https://dx.doi.org/10.1530/REP-17-0600.
- Archer S.L. Mitochondrial dynamics - mitochondrial fission and fusion in human diseases. N. Engl. J. Med. 2013; 369(23): 2236-51. https://dx.doi.org/10.1056/NEJMra1215233.
- Ciesielski G.L., Oliveira M.T., Kaguni L.S. Animal mitochondrial DNA replication. Enzymes. 2016; 39: 255-92. https://dx.doi.org/10.1016/bs.enz.2016.03.006.
- Popov L.-D. Mitochondrial biogenesis: an update. J. Cell. Mol. Med. 2020; 24(9): 4892-9. https://dx.doi.org/10.1111/jcmm.15194.
- Королькова А.И., Мишиева Н.Г., Мартазанова Б.А., Бурменская О.В., Веюкова М.А., Екимов А.Н., Трофимов Д.Ю., Абубакиров А.Н. Значимость копийности митохондриальной ДНК в клетках кумулуса пациенток позднего репродуктивного возраста. Акушерство и гинекология. 2019; 10: 108-14. https://dx.doi.org/10.18565/aig.2019.10.108-114.
- Cecchino G.N., Garcia-Velasco J.A. Mitochondrial DNA copy number as a predictor of embryo viability. Fertil. Steril. 2018: 111(2): 205-11. https://dx.doi.org/10.1016/j.fertnstert.2018.11.021.
- Hashimoto S., Morimoto N., Yam anaka M., Matsumoto H., Yamochi T., Goto H. et al. Quantitative and qualitative changes of mitochondria in human preimplantation embryos. J. Assist. Reprod. Genet. 2017; 34(5): 573-80. https://dx.doi.org/10.1007/s10815-017-0886-6.
- Ravichandran K., McCaffrey C., Grifo J., Morales A., Perloe M., Munne S. et al. Mitochondrial DNA quantification as a tool for embryo viability assessment: retrospective analysis of data from single euploid blastocyst transfers. Hum. Reprod. 2017; 32(6): 1282-92. https://dx.doi.org/10.1093/humrep/dex070.
- Fragouli E., McCaffrey C., Ravichandran K., Spath K., Grifo J.A., Munne S. et al. Clinical implications of mitochondrial DNA quantification on pregnancy outcomes: a blinded prospective non-selection study. Hum. Reprod. 2017; 32(11): 2340-7. https://dx.doi.org/10.1093/humrep/dex292.
- Lledo B., Ortiz J.A., Morales R., Garcia-Hernandez E., Ten J., Bernabeu A. et al. Comprehensive mitochondrial DNA analysis and IVF outcome. Hum. Reprod. Open. 2018; 2018(4): hoy023. https://dx.doi.org/10.1093/hropen/hoy023.
- Klimczak A.M., Pacheco L.E., Lewis K.E., Massahi N., Richards J.P., Kearns W.G. et al. Embryonal mitochondrial DNA: relationship to embryo quality and transfer outcomes. J. Assist. Reprod. Genet. 2018; 35(5): 871-7. https://dx.doi.org/10.1007/s10815-018-1147-z.
- Treff N.R., Zhan Y., Tao X., Olcha M., Han M., Rajchel J. et al. Levels of trophectoderm mitochondrial DNA do not predict the reproductive potential of sibling embryos. Hum. Reprod. 2017; 32(4): 954-62. https://dx.doi.org/10.1093/humrep/dex034.
- Victor A., Griffin D., Dardner K.G., Brake A., Zouves C., Barnes F. et al. Births from embryos with highly elevated levels of mitochondrial DNA. Reprod. Biomed. Online. 2019; 39(3): 403-12. https://dx.doi.org/10.1016/j.rbmo.2019.03.214.
- Victor A., Brake A.J., Tyndall J.C., Griffin D.K., Zouves C.G., Barnes F.L. et al. Accurate quantitation of mitochondrial DNA reveals uniform levels in human blastocysts irrespective of ploidy, age, or implantation potential. Fertil. Steril. 2017; 107(1): 34-42.e3. https://dx.doi.org/10.1016/j.fertnstert.2016.09.028.
- Lee Y.-X., Chen C.-H., Lin S.-Y., Lin Y.-H., Tzeng C.-R. Adjusted mitochondrial DNA quantification in human embryos may not be applicable as a biomarker of implantation potential. J. Assist. Reprod. Genet. 2019; 36(9): 1855-65. https://dx.doi.org/10.1007/s10815-019-01542-6.
- Shang W., Zhang Y., Shu M., Wang W., Ren L., Chen F. et al. Comprehensive chromosomal and mitochondrial copy number profiling in human IVF embryos. Reprod. Biomed. Online. 2018; 36(1); 67-74. https://dx.doi.org/10.1016/j.rbmo.2017.10.110.
- Wu F.S.Y., Weng S.P., Shen M.S., Ma P.C., Wu P.K., Lee N.C. Suboptimal trophectoderm mitochondrial DNA level is associated with delayed blastocyst development. J. Assist. Reprod. Genet. 2021; 38(3): 587-94. https://dx.doi.org/10.1007/s10815-020-02045-5.
- Королькова А.И., Мишиева Н.Г., Мартазанова Б.А., Бурменская О.В., Екимов А.Н., Трофимов Д.Ю., Веюкова М.А., Кириллова А.О., Абубакиров А.Н. Повышение эффективности программ ЭКО на основании определения копийности митохондриальной ДНК в трофэктодерме эмбрионов. Акушерство и гинекология. 2019; 3: 98-104. https://dx.doi.org/10.18565/aig.2019.3.98-104.