The characteristics of pregnancy course and delivery outcomes in patients after abortion: the results of a phase II study

Мұқаба

Дәйексөз келтіру

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Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

Objective: To study the characteristics of pregnancy course and delivery outcomes in patients after abortion.

Materials and methods: The study included 129 pregnant women who were divided into two groups and some subgroups. Group 1 included 60 pregnant women after medical abortion: subgroup 1A (n=41) consisted of patients who took the Superlymph suppositories in a dose of 25 units, and subgroup 1B (n=19) consisted of women who did not receive treatment with Superlymph. Group 2 (n=69) included pregnant women after surgical abortion: subgroup 2A (n=45) consisted of women who took Superlymph, subgroup 2B (n=24) included patients who did not take the medication.

Results: The patients after surgical abortion who did not receive Superlymph demonstrated a higher frequency of threatened miscarriage in the first trimester by 2.7 times (p=0.02). There were no significant differences in the frequency of threatened miscarriage in the second trimester in patients after medical abortion regardless of administration of the Superlymph medication (p=0.150). After artificial abortion followed by Superlymph therapy (subgroup 2A), the frequency of threatened miscarriage at a later gestation was twice lower than one in the subgroup of women without therapy (2B) (p<0.001). The frequency of threatened miscarriage was significantly higher in women who underwent surgical abortion without subsequent treatment (p=0.04). The course of the third trimester of pregnancy and delivery outcomes had no significant differences between the groups.

Conclusion: The frequency of miscarriage is higher among patients after surgical abortion. Conducting a course of cytokine therapy after both medical and surgical abortion can improve endometrial receptivity and the course of subsequent pregnancy.

Толық мәтін

Рұқсат жабық

Авторлар туралы

Yulia Dobrokhotova

N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia

Хат алмасуға жауапты Автор.
Email: pr.dobrohotova@mail.ru
ORCID iD: 0000-0002-7830-2290

Dr. Med. Sci., Professor, Head of the Department of Obstetrics and Gynecology, Institute of Surgery

Ресей, Moscow

Ekaterina Borovkova

N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia

Email: Katyanikitina@mail.ru
ORCID iD: 0000-0001-7140-262X

Dr. Med. Sci., Associate Professor, Professor at the Department of Obstetrics and Gynecology Institute of Surgery

Ресей, Moscow

Daria Safina

N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia

Email: dashadavydova1215@gmail.com

PhD Student, Department of Obstetrics and Gynecology Institute of Surgery

Ресей, Moscow

Naida Suleymanova

N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia

Email: naidasyleimanova1@mail.ru
ORCID iD: 0009-0008-6188-052X

PhD Student, Department of Obstetrics and Gynecology, Institute of Surgery

Ресей, Moscow

Әдебиет тізімі

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