Phenolic compounds in species of the genus Salvia L.

Cover Page

Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Introduction. Salvia oficinallis L. is a medicinal plant of the Lamiaceae family containing essential oils, flavonoids and tannins. S. oficinallis L. and S. sclarea L. are used in medicine because of their anti-inflammatory, antimicrobial properties.

The aim of the work was to conduct comparative qualitative and quantitative analyses of phenolic compounds in the leaves and stems of some species of the genus Salvia L.

Material and methods. The object of the study is the leaves and stems of some representatives of the genus Salvia L.: Salvia officinalis L., Salvia nemorosa L., Salvia dumetorum Andrz. ex Besser, Salvia verticillata L., Salvia nutans L. Qualitative determination of flavonoids was carried out by thin-layer chromatography. Quantitative determination of the amount of flavonoids in aqueous-alcoholic extracts from raw materials of some species of the genus Salvia was carried out by differential device in terms of the standard sample of cynaroside.

Results and discussion. The diagnostic feature of shas been confirmed. medicinal by the presence of water-alcohol extracts from leaves and stems of apigenin and luteolin on chromatographic profiles. The content of rutin in the leaves and stems of medicinal plants is not undermined by TLC analysis, however, it was reliably detected on chromatographic profiles of S. dumetorum in its leaves and stems.

Conclusion. The interspecific features of the spectra in the differential absorption curves make it possible to carry out chemical taxation of medicinal products, which increases the importance of spectrophotometry as a method of detecting authenticity for this type of medicinal plant raw materials

About the authors

Nikita Pavlovich Egorov

Samara State Medical University

Author for correspondence.
Email: n.egorov.2000@mail.ru
ORCID iD: 0009-0008-2349-1865
SPIN-code: 6191-2821

Postgraduate Student, Department of Pharmacognosy with Botany and the Basics of Phytotherapy

Russian Federation, Chapaevskaya street, 89, Samara, 443099

Vitaly Mikhailovich Ryzhov

Samara State Medical University

Email: v.m.ryzhov@samsmu.ru
ORCID iD: 0000-0002-8399-9328
SPIN-code: 1522-4652

Candidate of Pharmaceutical Sciences, Associate Professor, Associate Professor of the Department of Pharmacognosy with Botany and the Basics of Phytotherapy

Russian Federation, Chapaevskaya street, 89, Samara, 443099

Vladimir Alexandrovich Kurkin

Samara State Medical University

Email: v.a.kurkin@samsmu.ru
ORCID iD: 0000-0002-7513-9352
SPIN-code: 1974-5537

Professor, Head of the Department of Pharmacognosy with Botany and the Basics of Phytotherapy, Doctor of Pharmaceutical Sciences, Professor

Russian Federation, Chapaevskaya street, 89, Samara, 443099

Ksenia Nikolaevna Sazanova

Samara State Medical University

Email: k.n.sazanova@samsmu.ru
ORCID iD: 0000-0002-4287-8386
SPIN-code: 3867-6152

senior lecturer of the Department of Pharmacy Management and Economics – basic department «Pharmacies Plus», Candidate of Pharmaceutical Sciences

Russian Federation, Chapaevskaya street, 89, Samara, 443099

Tatiana Gennadievna Radomskaya

Samara State Medical University

Email: tatyanashko@yandex.ru
ORCID iD: 0009-0003-1996-0159
SPIN-code: 5443-4531

Postgraduate Student, Department of Pharmacognosy with Botany and the Basics of Phytotherapy

Russian Federation, Chapaevskaya street, 89, Samara, 443099

Elvira Maratovna Akhmadullina

Samara State Medical University

Email: elviragarifullina39@gmail.com
ORCID iD: 0009-0003-2313-5522

5th year student, Institute of Pharmacy

Russian Federation, Chapaevskaya street, 89, Samara, 443099

References

  1. Губанов И.А., Киселева К.В., Новиков В.С., Тихомиров В.Н. Иллюстрированный определитель растений Средней России. Покрытосеменные (двудольные: раздельнолепестные). М.: Товарищество науч. изд. КМК: Ин-т технол. исслед., 2004; 3: 143–8. [Gubanov I.A., Kiseleva K.V., Novikov V.S., Tikhomirov V.N. Illustrated determinant of plants of Central Russia. Angiosperms (Dicotyledons: deciduous). Moscow: Comradeship scientific publishing House. KMK: In-t technol. issledovanie, 2004; 3: 143–8 (in Russian)]
  2. Маевский П.Ф. Флора средней полосы европейской части России. 10-е издание. Москва: товарищество научных изданий КМК, 2006; 429–38. [Mayevsky P.F. Flora of the middle zone of the European part of Russia. 10th edition. Moscow: Association of Scientific Publications of the KMC, 2006; 429–38 (in Russian)]
  3. Растительные ресурсы России: Дикорастущие цветковые растения, их компонентный состав и биологическая активность. Семейства Caprifoliaceae – Lobeliaceae. Отв. редактор А.Л. Буданцев. СПб., М.: Товарищество научных изданий КМК, 2011; 4: 241–53. [Plant resources of Russia: Wild flowering plants, their component composition and biological activity. Families Caprifoliaceae – Lobeliaceae. Responsible editor A.L. Budantsev. St. Petersburg, Moscow: Partnership of scientific publications KMK, 2011; 4: 241–53 (in Russian)]
  4. Аминова М.З., Кароматов И.Д. Антибактериальные и противовоспалительные свойства лекарственного растения шалфей. Биология и интегративная медицина. 2018; 27 (10): 41–55. [Aminova M.Z., Karomatov I.D. Antibacterial and anti-inflammatory properties of the medicinal plant sage. Biology and Integrative Medicine. 2018; 27 (10): 41–55 (in Russian)]
  5. Волкова Н.Г., Абрамчук А.В., Карпухин М.Ю. Шалфей лекарственный (Salvia officinalis L.) – ценное эфирномасличное растение. Молодежь и наука. 2018; 3: 4–5. [Volkova N.G., Abramchuk A.V., Karpushin M.Yu. Common sage (Salvia officinalis L.) – a valuable essential oil plant. Youth and Science. 2018; 3: 4–5 (in Russian)]
  6. Baratta M., Dorman H., Deans S., Figueredo A., Barroso J., Ruberto G. Antimicrobal and antioxidant properties of some commercial essential oils. Flavour and Fragrance J. 1998; 13 (4): 235–44. [Баратта М., Дорман Х., Динс С., Фигередо А., Барросо Дж., Руберто Г. Антимикробные и антиоксидантные свойства некоторых эфирных масел. Flavour and Fragrance J. 1998; 13 (4): 235–44 (in American)]
  7. Кравченко И.В., Мулюкин М.А., Самойленко З.А., Макарова Т.А., Гулакова Н.М. Исследование содержания фотосинтетических пигментов и флавоноидных соединений в зеленой массе Salvia officinalis L. Проблемы ботаники Южной Сибири и Монголии. 2022; 21 (1): 94–8. [Kravchenko I.V., Mulyukin M.A., Samoylenko Z.A., Makarova T.A., Gulakova N.M. Study of the content of photosynthetic pigments and flavonoid compounds in the green mass of Salvia officinalis L. Problems of botany of Southern Siberia and Mongolia. 2022; 21 (1): 94–8 (in Russian)]
  8. Айтбеков Р.Н., Мурзахметова М.К., Жаманбаева Г.Т., Жусупова А.И. Фармакологические свойства Salvia officinalis и его компонентов. Фармация Казахстана. 2023; 5: 390–400. [Aitbekov R.N., Murzakhmetova M.K., Zhamanbaeva G.T., Zhusupova A.I. Pharmacological properties of Salvia officinalis and its components. Pharmacy of Kazakhstan. 2023; 5: 390–400 (in Kazakhstan)]
  9. Государственный реестр лекарственных средств. Режим доступа: https://grls.minzdrav.gov.ru/default.aspx [Дата обращения 10 августа, 2025]. [The State Register of Medicines. [Access mode: https://grls.minzdrav.gov.ru/default.aspx] (in Russian)]
  10. Куркина А.В. Флавоноиды фармакопейных растений: монография. Самара: ООО «Офорт», ГБОУ ВПО СамГМУ Минздравсоцразвития России, 2012; 290. [Kurkina A.V. Flavonoids of pharmacopoeial plants: a monograph. Samara: Ofort LLC, GBOU VPO SamSMU of the Ministry of Health and Social Development of Russia, 2012; 290 (in Russian)]
  11. Государственная Фармакопея Российской Федерации, XV изд. [Электронное издание]. Режим доступа: https://pharmacopoeia.regmed.ru/ [Дата обращения 10 августа, 2025]. [The State Pharmacopoeia of The Russian Federation, XV ed. [Electronic edition]. Access mode: https://pharmacopoeia.regmed.ru/ [Accessed 10 August, 2025] (in Russian)]
  12. Wellmann J., Tränkner C., Dostert N., Schwarze E.C., Hillebrand S., Ley J.P., & Winterhalter P. Comprehensive Metabolite Profiling of Salvia officinalis Using Ultra-High-Performance Liquid Chromatography–Electrospray Ionization–Quadrupole Time-of-Flight Mass Spectrometry. J. Agric. Food Chem. 2018; 66 (15): 3937–49. doi: 10.1021/acs.jafc.8b00581.
  13. Левая Я. К, Атажанова Г. А., Ивасенко С. А., Савпиева А.О., Смагулов М.К. Розмариновая кислота из Salvia stepposa и ее антирадикальная активность. Вестник Карагандинского университета. Серия: Биология. Медицина. География. 2023; 112 (4): 150–5. [Levaja Ja. K, Atazhanova G. A., Ivasenko S. A., Savpieva A.O., Smagulov M.K. Rosemary acid from Salvia stepposa and its antiradical activity. Bulletin of the Karaganda university. Biology. Medicine. Geography series. 2023; 112 (4): 150–5. doi: 10.31489/2023BMG4/150-155 (in Russian)]
  14. Бубенчикова В.Н., Кондратова Ю.А. Изучение фенольных соединений шалфея мутовчатого (Salvia verticillata L.). Башкирский химический журнал. 2008; 15 (2): 102–4. [Bubenchikova V.N., Kondratova Yu.A. Study of phenolic compounds of whorled sage (Salvia verticillata L.). Bashkir Chemical J. 2008; 15 (2): 102–4 (in Russian)]

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2026 Russkiy Vrach Publishing House